anti-Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G) 抗体

Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. 再加上,我们可以发CACNA1G 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CACNA1G 8913 O43497
CACNA1G 12291  
CACNA1G 29717 O54898
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Showing 10 out of 143 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB Immunohistochemistry with Brain, cortex tissue at an antibody concentration of 2.5µg/ml using anti-CACNA1G antibody (ARP35566_P050) WB Suggested Anti-CACNA1G Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Spleen 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB Western blot analysis of Cav3.1 expression in HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
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非结合性 IHC, IHC (p) Immunohistochemistry: CACNA1G Antibody [NBP1-86611] - Immunohistochemical staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. 0.1 mL Log in to see 10至13个工作日
$491.63
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非结合性 IHC, IHC (p), WB Anti-CACNA1G / Cav3.1 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958959 concentration 41396 ug/ml. Anti-CACNA1G / Cav3.1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml. This image was taken for the unconjugated form of thi ... 50 μg Log in to see 11至14个工作日
$727.83
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山羊 非结合性 ELISA, WB   100 μg Log in to see 6至7个工作日
$242.88
详细
小鼠 HRP ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Cav3.1 Monoclonal Antibody, Clone S178A-9 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Cav3.1 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:200 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Cell Membrane, Membrane, Cytoplasm, Nucleoplasm. Magnification: 60X. Western Blot analysis of Rat brain membrane lysate showing detection of Cav3.1 Calcium Channel protein using Mouse Anti-Cav3.1 Calcium Channel Monoclonal Antibody, Clone S178A-9 . Primary Antibody: Mouse Anti-Cav3.1 Calcium Channel Monoclonal Antibody  at 1:1000. 100 μg Log in to see 2至3个工作日
$422.40
详细
小鼠 FITC ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Cav3.1 Monoclonal Antibody, Clone S178A-9 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Cav3.1 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:200 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Cell Membrane, Membrane, Cytoplasm, Nucleoplasm. Magnification: 60X. Western Blot analysis of Rat brain membrane lysate showing detection of Cav3.1 Calcium Channel protein using Mouse Anti-Cav3.1 Calcium Channel Monoclonal Antibody, Clone S178A-9 . Primary Antibody: Mouse Anti-Cav3.1 Calcium Channel Monoclonal Antibody  at 1:1000. 100 μg Log in to see 2至3个工作日
$426.80
详细
小鼠 Alkaline Phosphatase (AP) ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Cav3.1 Monoclonal Antibody, Clone S178A-9 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Cav3.1 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:200 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Cell Membrane, Membrane, Cytoplasm, Nucleoplasm. Magnification: 60X. Western Blot analysis of Rat brain membrane lysate showing detection of Cav3.1 Calcium Channel protein using Mouse Anti-Cav3.1 Calcium Channel Monoclonal Antibody, Clone S178A-9 . Primary Antibody: Mouse Anti-Cav3.1 Calcium Channel Monoclonal Antibody  at 1:1000. 100 μg Log in to see 2至3个工作日
$429.00
详细
小鼠 Biotin ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Cav3.1 Monoclonal Antibody, Clone S178A-9 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Cav3.1 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:200 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Cell Membrane, Membrane, Cytoplasm, Nucleoplasm. Magnification: 60X. Western Blot analysis of Rat brain membrane lysate showing detection of Cav3.1 Calcium Channel protein using Mouse Anti-Cav3.1 Calcium Channel Monoclonal Antibody, Clone S178A-9 . Primary Antibody: Mouse Anti-Cav3.1 Calcium Channel Monoclonal Antibody  at 1:1000. 100 μg Log in to see 2至3个工作日
$431.20
详细
小鼠 PE ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Cav3.1 Monoclonal Antibody, Clone S178A-9 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Cav3.1 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:200 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Cell Membrane, Membrane, Cytoplasm, Nucleoplasm. Magnification: 60X. Western Blot analysis of Rat brain membrane lysate showing detection of Cav3.1 Calcium Channel protein using Mouse Anti-Cav3.1 Calcium Channel Monoclonal Antibody, Clone S178A-9 . Primary Antibody: Mouse Anti-Cav3.1 Calcium Channel Monoclonal Antibody  at 1:1000. 100 μg Log in to see 2至3个工作日
$432.30
详细

引用最多的anti-CACNA1G 抗体

  1. Mammalian Monoclonal CACNA1G Primary Antibody for ISt, IHC - ABIN1304582 : Curran, Musa, Kline, Makara, Little, Higgins, Hund, Band, Mohler: Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria. in The Journal of biological chemistry 2015 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal CACNA1G Primary Antibody for IF (p), IHC (p) - ABIN680608 : Lu, Long, Zhou, Xu, Hu, Li: Mibefradil reduces blood glucose concentration in db/db mice. in Clinics (São Paulo, Brazil) 2014 (PubMed)

  3. Human Polyclonal CACNA1G Primary Antibody for IHC, IHC (p) - ABIN4286744 : Strandberg, Cui, Rath, Liu, Silverman, Liu, Siragam, Ackerley, Su, Yan, Capecchi, Biavati, Accorroni, Yuen, Quattrone, Lung, Jaeggi, Backx, Deber, Hamilton: Congenital heart block maternal sera autoantibodies target an extracellular epitope on the α1G T-type calcium channel in human fetal hearts. in PLoS ONE 2013 (PubMed)

  4. Cow (Bovine) Polyclonal CACNA1G Primary Antibody for ELISA - ABIN4286741 : Ernst, Zhang, Yoo, Ernst, Noebels: Genetic enhancement of thalamocortical network activity by elevating alpha 1g-mediated low-voltage-activated calcium current induces pure absence epilepsy. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 (PubMed)

  5. Human Polyclonal CACNA1G Primary Antibody for IHC, IHC (p) - ABIN4286742 : Borahay, Kilic, Yallampalli, Snyder, Hankins, Al-Hendy, Boehning: Simvastatin potently induces calcium-dependent apoptosis of human leiomyoma cells. in The Journal of biological chemistry 2014 (PubMed)

更多抗CACNA1G的相互作用对抗体

Human Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G) interaction partners

  1. T-type channel calcium influx invokes a novel dynamic interaction between CaM and Cav3.1 channels to trigger a signaling cascade that leads to alphaCaMKII activation.

  2. human Cav3.1, Cav3.2, and Cav3.3 T-type channels specifically associate with CaM at helix 2 of the gating brake in the I-II linker of the channels.

  3. Here we show that T-type channels Cav3.1 and Cav3.2 (显示 CACNA1H 抗体) are present in the lung and PASMCs from iPAH patients and control subjects. The blockade of T-type channels by the specific blocker, TTA-A2, prevents cell cycle progression and PASMCs growth

  4. Cacna1g exclusively expressed in serosal PDGFRalpha+ cells is a new pathological marker for gastrointestinal diseases.

  5. Electrophysiological studies showed a significant increase in Cd(2 (显示 CD2 抗体)+) and manganese (Mn(2+)) currents through the CaV3.1 mutants as well as a reduction in the inhibitory effect of Cd(2 (显示 CD2 抗体)+) on the Ca(2 (显示 CA2 抗体)+) current.

  6. The results of this study provide support for Cacna1g as a genetic modifier in a mouse model of Dravet syndrome and suggest that Cav3.1 may be a potential molecular target for therapeutic intervention in patients

  7. CACNA1G variant is associated with differential antiepileptic drug response in childhood absence epilepsy.

  8. CaV3.1, CaV3.2 (显示 CACNA1H 抗体) and CaV3.3 (显示 CACNA1I 抗体) channels, are best recognized for their negative voltage of activation and inactivation thresholds that allow them to operate near the resting membrane potential of neurons.

  9. In 2 families with autosomal dominant SCA, a CACNA1G mutation p.Arg1715His was found at S4 of repeat IV, the voltage sensor of the CaV3.1 which shifted it toward a positive potential.

  10. A Recurrent Mutation in CACNA1G Alters Cav3.1 T-Type Calcium-Channel Conduction and Causes Autosomal-Dominant Cerebellar Ataxia.

Mouse (Murine) Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G) interaction partners

  1. Membrane-protein extraction and use of an intracellular protein (显示 CKAP2 抗体)-transport inhibitor showed that GDF-15 (显示 GDF15 抗体) promoted CaV3.1 and CaV3.3 (显示 CACNA1I 抗体) alpha-subunit (显示 POLG 抗体) expression by trafficking to the membrane.

  2. Cacna1g exclusively expressed in serosal PDGFRalpha+ cells is a new pathological marker for gastrointestinal diseases.

  3. Data, including data from studies using knockout mice, suggest that acetylcholine- (Ach (显示 FGFR3 抗体)-)induced vasorelaxation/vasodilatation of intrapulmonary arteries is reduced in pulmonary hypertension, but is still dependent on Cav3.1 activity; thus, Cav3.1 contributes to intrapulmonary vascular reactivity by controlling calcium signaling in arterial endothelium and Ach (显示 FGFR3 抗体)-induced vasorelaxation/vasodilatation.

  4. These results provide support for Cacna1g as an epilepsy modifier gene and suggest that modulation of Cav3.1 may be an effective therapeutic strategy.

  5. Localized Cav3.1 knockdown in the medial septum selectively enhanced object exploration, whereas the null mutant (KO) mice showed enhanced-object exploration as well as open-field exploration.

  6. GluA4 (显示 GRIA4 抗体) subunits are required to produce an EPSC-triggerable postsynaptic action potentials after the presynaptic action potential, while Cav3.1 expression is needed to establish the driver function of L5B-POm synapses at hyperpolarized membrane potentials

  7. Mice deficient for CaV3.1 were resistant to the induction of experimental autoimmune encephalomyelitis and had reduced productions of the granulocyte-macrophage colony-stimulating factor (显示 CSF2 抗体) by central nervous system-infiltrating Th1 (显示 HAND1 抗体) and Th17 cells.

  8. Cross-frequency coupling between low-frequency and gamma rhythms was pronounced in wild-type but not in CaV3.1 knockouts, suggesting that the presence of CaV3.1 channels is a key element in the pathophysiology of trigeminal neuropathic pain.

  9. CaV3.1 and CaV3.2 (显示 CACNA1H 抗体) are substrates for EHD3 (显示 EHD3 抗体)-dependent protein trafficking in heart

  10. This study reported on the cloning and characterization of a proximal promoter region and initiated the analysis of transcription factors that control CaV (显示 CA5A 抗体) 3.1 channel expression using the murine Cacna1g gene as a model.

Cow (Bovine) Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G) interaction partners

  1. CaV3.1 structural analysis and comparison to CaV1.2 (显示 CACNA1C 抗体) channel

CACNA1G 抗原简介

蛋白简介

Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with CACNA1G

  • calcium voltage-gated channel subunit alpha1 G (CACNA1G) 抗体
  • calcium channel, voltage-dependent, T type, alpha 1G subunit (cacna1g) 抗体
  • calcium channel, voltage-dependent, T type, alpha 1G subunit L homeolog (cacna1g.L) 抗体
  • calcium channel, voltage-dependent, T type, alpha 1G subunit (Cacna1g) 抗体
  • calcium voltage-gated channel subunit alpha1 G (Cacna1g) 抗体
  • a1G 抗体
  • alpha-1G 抗体
  • Ca(v)3.1 抗体
  • Ca(V)T.1 抗体
  • CACNA1G 抗体
  • Cav3.1 抗体
  • Cav3.1d 抗体
  • mKIAA1123 抗体
  • NBR13 抗体
  • [a]1G 抗体

Protein level used designations for CACNA1G

voltage-dependent calcium channel alpha 1G subunit , calcium channel, voltage-dependent, T type, alpha 1G subunit , calcium channel voltage-dependent T type Cav3.1, alpha 1g subunit , cav3.1c , voltage-dependent T-type calcium channel subunit alpha-1G , voltage-gated calcium channel subunit alpha Cav3.1 , calcium channel, voltage-dependent, alpha 1G subunit

GENE ID SPECIES
455128 Pan troglodytes
563904 Danio rerio
769385 Gallus gallus
100070000 Equus caballus
100346309 Oryctolagus cuniculus
100462914 Xenopus laevis
8913 Homo sapiens
12291 Mus musculus
29717 Rattus norvegicus
491083 Canis lupus familiaris
282411 Bos taurus
100513431 Sus scrofa
100728128 Cavia porcellus
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