CACNA1G 抗体 (AA 901-1000)
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北京 101111
Quick Overview for CACNA1G 抗体 (AA 901-1000) (ABIN680608)
抗原
See all CACNA1G 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 901-1000
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特异性
- Possible cross-reactivity with CACNA1H and CACNA1I
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Pig,Guinea Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CACNA1G/Cav31
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Mibefradil reduces blood glucose concentration in db/db mice." in: Clinics (São Paulo, Brazil), Vol. 69, Issue 1, pp. 61-7, (2014) (PubMed).
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: "Mibefradil reduces blood glucose concentration in db/db mice." in: Clinics (São Paulo, Brazil), Vol. 69, Issue 1, pp. 61-7, (2014) (PubMed).
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- CACNA1G (Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G))
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别名
- CACNA1G
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背景
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Synonyms: NBR13, Cav3.1, Ca(V)T.1, Voltage-dependent T-type calcium channel subunit alpha-1G, Cav3.1c, Voltage-gated calcium channel subunit alpha Cav3.1, CACNA1G, KIAA1123
Background: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by mibefradil. A particularity of this type of channel is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.
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基因ID
- 8913
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UniProt
- O43497
抗原
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