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CACNA1I encodes the pore-forming alpha subunit of a voltage gated calcium channel. 再加上，我们可以发CACNA1I 蛋白 (5)和数多这个蛋白质的别的产品。
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Membrane-protein extraction and use of an intracellular protein (显示 CKAP2 抗体)-transport inhibitor showed that GDF-15 (显示 GDF15 抗体) promoted CaV3.1 (显示 CACNA1G 抗体) and CaV3.3 alpha-subunit (显示 POLG 抗体) expression by trafficking to the membrane.
Extracellular pressure increases [Ca(2 (显示 CA2 抗体)+)]i via Cav3.3, driving a PKC-beta (显示 PRKCB 抗体)- IKK (显示 CHUK 抗体)- IkB (显示 NFKBIB 抗体)-NF-kB pathway that stimulates cancer cell proliferation
using Ca(V)3.3(-/-) mice we found that Ca(V)3.3 channels trigger synaptic plasticity in reticular thalamic neurons
data identify a central role for Ca(V)3.3 channels in the rhythmogenic properties of the sleep-spindle generator and provide a molecular target to elucidate the roles of sleep spindles for brain function and development.
analyses suggest that a single copy of Chr22: 39665939G > A CACNA1I has the capacity to disrupt CaV3.3 channel-dependent functions, including rebound bursting in TRN (显示 TNPO1 抗体) neurons, with potential implications for schizophrenia pathophysiology.
low-voltage activation characteristics of CaV3.3 channels
CACNA1I is a risk gene for schizophrenia in the Han Chinese population
human Cav3.1, Cav3.2, and Cav3.3 T-type channels specifically associate with CaM at helix 2 of the gating brake in the I-II linker of the channels.
significant association exists between the CACNA1I gene and schizophrenia in the Uighur Chinese population
CACNA1I variant is associated with differential antiepileptic drug response in childhood absence epilepsy.
CaV3.1 (显示 CACNA1G 抗体), CaV3.2 (显示 CACNA1H 抗体) and CaV3.3 channels, are best recognized for their negative voltage of activation and inactivation thresholds that allow them to operate near the resting membrane potential of neurons.
Ethanol primarily affects the CaV3.2 (显示 CACNA1H 抗体) isoform of T-type Ca(2 (显示 CA2 抗体))+ channels, acting through protein kinase C (显示 PKC 抗体).
Specific contribution of human T-type calcium channel isotypes (alpha(1G (显示 CACNA1G 抗体)), alpha(1H) and alpha(1I)) to neuronal excitability.
This gene encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by this protein is characterized by a slower activation and inactivation compared to other T-type calcium channels. This protein may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants.
alpha1I T-type calcium channel subunit
, calcium channel, voltage-dependent, T type, alpha 1I subunit
, voltage-dependent T-type calcium channel alpha-1I subunit
, voltage-dependent T-type calcium channel subunit alpha-1I-like
, low voltage-activated T-type calcium channel alpha-1 subunit (CACNA1I)
, low-voltage-activated calcium channel alpha13.3
, calcium channel, voltage-dependent, alpha 1I subunit
, voltage-dependent T-type calcium channel subunit alpha-1I
, voltage-gated calcium channel subunit alpha Cav3.3
, hypothetical gene supported by NM_020084
, voltage-dependent calcium channel