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CACNA1I 抗体 (Cytoplasmic Domain)

CACNA1I 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN350147
发货至: 中国
  • 抗原 See all CACNA1I 抗体
    CACNA1I (Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit (CACNA1I))
    抗原表位
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cytoplasmic Domain
    适用
    • 9
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 8
    • 2
    克隆类型
    • 8
    • 2
    多克隆
    标记
    • 10
    This CACNA1I antibody is un-conjugated
    应用范围
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Specific for CACNA1I.
    交叉反应
    人, 小鼠, 大鼠
    交叉反应 (详细)
    Other species not yet tested.
    纯化方法
    IgG
    免疫原
    A synthetic peptide from a cytoplasmic domain of human CACNA1I conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
    亚型
    IgG
    Top Product
    Discover our top product CACNA1I Primary Antibody
  • 应用备注
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    CACNA1I (Calcium Channel, Voltage Dependent, T Type, alpha 1I Subunit (CACNA1I))
    别名
    CACNA1I (CACNA1I 产品)
    别名
    CACNA1L antibody, Ca(V)3.3 antibody, Cav3.3 antibody, ca(v)3.3 antibody, si:ch211-51h13.1 antibody, Ca(v)3.3 antibody, calcium voltage-gated channel subunit alpha1 I antibody, voltage-dependent T-type calcium channel subunit alpha-1I antibody, calcium channel, voltage-dependent, alpha 1I subunit antibody, calcium channel, voltage-dependent, T type, alpha 1I subunit antibody, CACNA1I antibody, LOC100555412 antibody, Cacna1i antibody, cacna1i antibody
    背景
    Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Isoform alpha-1I gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. Gates in voltage ranges similar to, but higher than alpha 1G or alpha 1H. Subcellular location: Membrane, Multi-pass membrane protein. Tissue specificity: Brain specific,Alpha Subunit,Voltage-dependent T-type calcium channel subunit alpha-1I, Voltage-gated calcium channel subunit alpha Cav3.3
    UniProt
    Q9P0X4
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