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The product of APOA1BP interacts with apolipoprotein A-I (apoA-I), the major apolipoprotein of high-density lipoproteins (HDLs).
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Human Polyclonal APOA1BP Primary Antibody for ELISA, WB - ABIN451664
Ritter, Buechler, Boettcher, Barlage, Schmitz-Madry, Orsó, Bared, Schmiedeknecht, Baehr, Fricker, Schmitz: Cloning and characterization of a novel apolipoprotein A-I binding protein, AI-BP, secreted by cells of the kidney proximal tubules in response to HDL or ApoA-I. in Genomics 2002
Study shows a homozygous mutation in the APOA1BP is associated with a lethal infantile leukoencephalopathy.This is the first report of a defect in the nicotinamide nucleotide repair system in humans.
AIBp contributes to mitotic entry and bipolar spindle assembly.
AIBP accelerates cholesterol efflux from endothelial cells to HDL and thereby regulates angiogenesis
Taken together, the current study demonstrates that APN (显示 ANPEP 抗体) might protect against atherosclerosis by increasing HDL (显示 HSD11B1 抗体) assembly through enhancing ABCA1 (显示 ABCA1 抗体) pathway and apoA-1 (显示 APOA1 抗体) synthesis in the liver.
Loss of Apoa1bp increased vascular density and facilitated the recovery of blood vessel perfusion function in a hindlimb ischemia model.
The Aibp gene encodes two different proteins, both targeted to the mitochondria (mAIBP) and cytosol (cAIBP) confirming the presence of dehydratase and epimerase in the cytosol and mitochondria.
AI-BP plays an important role in capacitation possibly providing a link between protein phosphorylation and cholesterol efflux.
findings demonstrate that secreted AIBP positively regulates cholesterol efflux from endothelial cells and that effective cholesterol efflux is critical for proper angiogenesis [AIBP]
The product of this gene interacts with apolipoprotein A-I (apoA-I), the major apolipoprotein of high-density lipoproteins (HDLs). It is secreted into some bodily fluids, and its synthesis and secretion are stimulated in vitro by incubating cells with apoA-I. The human genome contains related pseudogenes.
, NAD(P)H-hydrate epimerase
, NAD(P)HX epimerase
, apoA-I binding protein
, apolipoprotein A-I-binding protein
, yjeF N-terminal domain-containing protein 1
, apolipoprotein A-I interacting protein
, apoliprotein A-I binding protein
, apoliprotein A-I-interacting protein
, apolipoprotein A-I binding protein