anti-Anillin, Actin Binding Protein (ANLN) 抗体

Required for cytokinesis. 再加上,我们可以发Anillin 试剂盒 (8)Anillin 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ANLN 54443 Q9NQW6
ANLN 68743 Q8K298
ANLN 363031  
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antibodies-online.cn销售最多的anti-Anillin 抗体

Showing 10 out of 77 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 ICC, IF, IHC, IHC (p), WB Immunohistochemistry: Anillin Antibody [NBP2-33857] - Immunohistochemical staining of human testis shows strong nuclear positivity in cells in seminiferous ducts. Western Blot: Anillin Antibody [NBP2-33857] - Lane 1: Marker [kDa] 220, 112, 84, 47, 32, 26, 17.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp 0.1 mL Log in to see 10至13个工作日
非结合性 ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: Anillin Antibody [NBP1-31060] - Paraffin-embedded mouse brain; antibody. Immunohistochemistry: Anillin Antibody [NBP1-31060] - Paraffin-embedded U87 xenograft. 100 μL Log in to see 8至11个工作日
山羊 非结合性 ELISA, WB Western Blot: Anillin Antibody [ABIN42806699] - Western Blot analysis of ANLN in Mouse Brain lysate using ABIN42806699 (1ug/ml). Western Blot: Anillin Antibody [ABIN42806699] - (1ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7至9个工作日
Cow 山羊 非结合性 EIA, IHC (p), WB   0.1 mg Log in to see 8至11个工作日
Bat 山羊 非结合性 ELISA, WB 100 μg Log in to see 7至9个工作日
山羊 非结合性 IHC (p), IHC, ELISA Immunohistochemistry-Paraffin: Anillin Antibody [ABIN250023] - 10ug/ml staining of paraffin embedded Human Kidney. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining. Flow Cytometry: Anillin Antibody  - Analysis of paraformaldehyde fixed MCF7 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody. 0.1 mg Log in to see 7至9个工作日
山羊 非结合性 WB   0.1 mg Log in to see 8至11个工作日
非结合性 IHC (p), IP, IHC, WB Immunohistochemistry-Paraffin: Anillin Antibody [ABIN2611316] - Human colon carcinoma. Antibody used at a dilution of 1:1000 (1ug/ml). 100 μL Log in to see 7至9个工作日
非结合性 IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded human placenta labeled with Anti-Anillin Polyclonal Antibody, Unconjugated (ABIN872314) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3至7个工作日
Cow 山羊 非结合性 ELISA   100 μg Log in to see 7至9个工作日

通过反应活性、应用领域、克隆类型和共轭标记 ANLN 抗体

特性 应用范围 宿主 克隆类型 标记
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Mouse (Murine) , , ,

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Rat (Rattus) ,

引用最多的anti-Anillin 抗体

  1. Human Polyclonal Anillin Primary Antibody for ICC, IF - ABIN4280671 : Hjelm, Forsström, Igel, Johannesson, Stadler, Lundberg, Ponten, Sjöberg, Rockberg, Schwenk, Nilsson, Johansson, Uhlén: Generation of monospecific antibodies based on affinity capture of polyclonal antibodies. in Protein science : a publication of the Protein Society 2011 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal Anillin Primary Antibody for ELISA, WB - ABIN4280669 : Hall, Todd, Hyland, McDade, Grabsch, Dattani, Hillan, Russell: The septin-binding protein anillin is overexpressed in diverse human tumors. in Clinical cancer research : an official journal of the American Association for Cancer Research 2005 (PubMed)

  3. Human Polyclonal Anillin Primary Antibody for IHC (p), IHC - ABIN250023 : Oegema, Savoian, Mitchison, Field: Functional analysis of a human homologue of the Drosophila actin binding protein anillin suggests a role in cytokinesis. in The Journal of cell biology 2000 (PubMed)


Human Anillin, Actin Binding Protein (ANLN) interaction partners

  1. Knockdown of ANLN in liver cells blocks cytokinesis and inhibits development of liver tumors.

  2. Authors found that decreasing Ran-GTP (显示 AK3 抗体) levels or tethering active Ran to the equatorial membrane affects anillin's localization and causes cytokinesis phenotypes.

  3. Anillin (ANLN) expression in tumor cells is correlated to poor prognosis in breast cancer patients, independent of Ki-67 (显示 MKI67 抗体) or tumor size.

  4. ANLN expression is elevated in colorectal cancer and has a strong potential to act as a biomarker for the prognosis of colorectal cancer.

  5. Findings indicate that miR (显示 MLXIP 抗体)-497 is a potent tumor suppressor that inhibits cancer phenotypes by targeting ANLN and HSPA4L (显示 HSPA4L 抗体) in NPC (显示 NPC1 抗体).

  6. High nuclear expression of anillin (ANLN) is an independent predictor of poor disease-specific survival and it is a useful prognostic marker of urothelial carcinoma of the upper urinary tract (UCUT).

  7. Data suggest that anillin (ANLN) could be involved in breast cancer progression and a potential target candidate in breast cancer.

  8. Identification 4 novel and 18 known exonic ANLN variants associated with carotid intima-media thickness at bifurcation.

  9. Anillin regulates intercellular adhesion in model human epithelia by mechanisms involving the suppression of JNK (显示 MAPK8 抗体) activity and controlling the assembly of the perijunctional cytoskeleton.

  10. The sequestration of anillin by astral microtubules might alter the organization of cortical proteins to polarize cells for cytokinesis

Mouse (Murine) Anillin, Actin Binding Protein (ANLN) interaction partners

  1. Loss of ANLN expression is associated with tumorigenesis in liver.

  2. Knockdown of ANLN in liver cells blocks cytokinesis and inhibits development of liver tumors.

  3. data suggest that anillin is an essential intracellular component that maintains the integrity of asymmetric division in mouse oocytes.

  4. Anillin is excluded from the cortex of first polar body, enriched in the cytokinetic ring that severs the polar body from the oocyte. In meiosis II, anillin is enriched in a cortical stripe coincident with and overlying the meiotic spindle midzone.

  5. Results show that targeting of mDia2 (显示 DIAPH3 抗体) to the cleavage furrow requires not only its binding to RhoA (显示 RHOA 抗体) but also its diaphanous-inhibitory domain, and identify anillin as a novel mDia2 (显示 DIAPH3 抗体) interaction partner.

Fruit Fly (Drosophila melanogaster) Anillin, Actin Binding Protein (ANLN) interaction partners

  1. we show that the transition from the actomyosin contractile ring to the midbody ring proceeds via a previously uncharacterized maturation process that requires opposing mechanisms of removal and retention of the scaffold protein (显示 HOMER1 抗体) Anillin.

  2. Anillin is required for complete closure of the contractile ring and formation of the midbody ring during cytokinesis.

  3. the anillin pleckstrin (显示 PLEK 抗体) homology domain has two functions: targeting anillin to the plasma membrane furrow by binding to phosphatidylinositol phosphate lipids to maintain furrow organization and recruiting septins to the furrow.

  4. Data suggest that Cindr and Anillin cooperate to promote intercellular bridge stability during incomplete cytokinesis in Drosophila melanogaster.

  5. Results show that the anillin-septin and cadherin-catenin complexes can serve as alternative cassettes to promote tight physical coupling of F-actin and myosin II to the cleavage furrow and successful completion of cytokinesis.

  6. anillin has a role in spatially regulating the contractile activity of myosin II during cytokinesis

  7. important role for scraps in scaffolding cleavage furrow components, directly stabilizing intracellular bridges

  8. A novel RhoGEF(Pbl)-dependent input promotes the simultaneous association of anillin with the plasma membrane, septins, and microtubules, independently of F-actin.

  9. anillin and Peanut are involved in pseudocleavage furrow ingression in syncytial embryos, a process that is regulated by Ran

Xenopus laevis Anillin, Actin Binding Protein (ANLN) interaction partners

  1. The authors propose that anillin is required for proper Rho-GTP (显示 AK3 抗体) distribution at cell-cell junctions and for maintenance of a robust apical actomyosin belt, which is required for cell-cell junction integrity.

  2. anillin has a role in spatially regulating the contractile activity of myosin II during cytokinesis

Zebrafish Anillin, Actin Binding Protein (ANLN) interaction partners

  1. The study provides the in vivo evidence for the requirement of Anillin during asymmetric neurogenic divisions.

Anillin (ANLN) 抗原简介


Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression (By similarity).

Gene names and symbols associated with ANLN

  • anillin actin binding protein (ANLN) 抗体
  • anillin, actin binding protein (Anln) 抗体
  • anillin actin binding protein (anln) 抗体
  • scraps (scra) 抗体
  • anillin actin binding protein L homeolog (anln.L) 抗体
  • anillin, actin binding protein (anln) 抗体
  • 1110037A17Rik 抗体
  • 2900037I21Rik 抗体
  • Abp8 抗体
  • ani 抗体
  • anil 抗体
  • anillin 抗体
  • ANLN 抗体
  • C78101 抗体
  • CG2092 抗体
  • Dmel\\CG2092 抗体
  • l(2)03427 抗体
  • l(2)43Ec 抗体
  • l(2)k08255 抗体
  • RGD1561367 抗体
  • Scra 抗体
  • scraps 抗体
  • si:ch211-197n10.2 抗体
  • wu:fb74d05 抗体
  • wu:fd10d09 抗体
  • wu:fi41f04 抗体

Protein level used designations for ANLN

actin-binding protein anillin , anillin, actin binding protein , anillin, actin binding protein (scraps homolog, Drosophila) , actin-binding protein anillin-like , Actin-binding protein 8 , CG2092-PA , CG2092-PB , CG2092-PC , anillin , annilin , lethal (2) k08255 , scra-PA , scra-PB , scra-PC , contractile ring component anillin

54443 Homo sapiens
420738 Gallus gallus
463351 Pan troglodytes
482401 Canis lupus familiaris
518274 Bos taurus
706404 Macaca mulatta
100351074 Oryctolagus cuniculus
100387382 Callithrix jacchus
100469164 Ailuropoda melanoleuca
68743 Mus musculus
100329114 Xenopus (Silurana) tropicalis
100548396 Meleagris gallopavo
100558878 Anolis carolinensis
100581939 Nomascus leucogenys
35696 Drosophila melanogaster
398569 Xenopus laevis
100523340 Sus scrofa
363031 Rattus norvegicus
101116045 Ovis aries musimon
562517 Danio rerio
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