anti-Amiloride-Sensitive Cation Channel 3 (ACCN3) 抗体

ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. 再加上,我们可以发Amiloride-Sensitive Cation Channel 3 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ACCN3 286920 O35240
ACCN3 9311 Q9UHC3
ACCN3 171209 Q6X1Y6
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Showing 10 out of 54 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB WB Suggested Anti-ACCN3 <br /> Antibody Titration: 2.5 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: Human Kidney 100 μL Log in to see 2至3个工作日
$229.00
详细
Cow 非结合性 IHC (p), WB 100 μg Log in to see 7至9个工作日
$493.17
详细
非结合性 WB Anti-ASIC3 antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: Rat Testis Tissue Lysate Lane 3: U87 Cell Lysate Lane 4: NEURO Cell Lysate Lane 5: SMMC Cell Lysate 100 μg Log in to see 4至6个工作日
$280.00
详细
非结合性 WB ACCN3 Antibody (N-term)  western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the ACCN3 antibody detected the ACCN3 protein (arrow). 400 μL Log in to see 10至11个工作日
$324.50
详细
非结合性 ELISA, WB 100 μL Log in to see 16 Days
$181.73
详细
非结合性 IHC, IHC (p) Immunohistochemistry-Paraffin: Amiloride-sensitive cation channel 3 Antibody [NBP2-14322] - Staining of human cerebellum shows moderate cytoplasmic positivity in Purkinje cells. Immunohistochemistry-Paraffin: Amiloride-sensitive cation channel 3 Antibody  - Staining of human cerebellum shows moderate cytoplasmic positivity in Purkinje cells. 0.1 mL Log in to see 10至13个工作日
$491.63
详细
非结合性 IHC, WB ACCN3 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of renal tubule (arrows) in Human Kidney. Magnification is at 400X ACCN3 antibody used at 2.5 ug/ml to detect target protein. 100 μg Log in to see 2至3个工作日
$388.93
详细
非结合性 IHC, ELISA, WB 100 μg Log in to see 2至3个工作日
$446.88
详细
大鼠 豚鼠 非结合性 ICC, IHC (fro), IF, IHC Immunocytochemistry/Immunofluorescence: Amiloride-sensitive cation channel 3 Antibody [ABIN250611] - ASIC3 expression in normal and CF human lung tissues by immunofluorescence microscopy. Normal (top panels A-C) and CF human lung sections (bottom panels D-F) were labeled with a specific antibody against ASIC3 (green channel) and the DNA-selective Hoechst dye (blue channel). A and D, normal and CF human lung sections imaged following incubation with the mixture of anti-ASIC3 antibody and immunopeptide. Shown are normal (B) and CF (E) alveolar structures at a small magnification. ASIC3 expression was detected in both types I and II alveolar cells. Shown are normal (C) and CF (F) alveolar structures at a large magnification. Scale bars equal 10 um in A, B, D, and E and 20 um in C and F. 0.05 mL Log in to see 7至9个工作日
$345.00
详细
大鼠 豚鼠 非结合性 ICC, IHC   50 μL Log in to see 7至9个工作日
$669.17
详细

通过反应活性、应用领域、克隆类型和共轭标记 ACCN3 抗体

特性 应用范围 宿主 克隆类型 标记
Rat (Rattus) ,
,

Human ,
,

, , , , ,
Mouse (Murine)


更多抗Amiloride-Sensitive Cation Channel 3的相互作用对抗体

Horse (Equine) Amiloride-Sensitive Cation Channel 3 (ACCN3) interaction partners

  1. Muscles from horses submitted to strenuous exercises produce lactic acid, which may induce variable pain through ACCN (显示 ACCN1 抗体) differential properties; ACCN1 (显示 ACCN2 抗体) and ACCN3 genes have an ubiquitous expression but ACCN1 (显示 ACCN2 抗体) is more highly expressed in the spinal cord.

Human Amiloride-Sensitive Cation Channel 3 (ACCN3) interaction partners

  1. the data demonstrate a functional link between ASICs and [Ca(2 (显示 CA2 抗体)+)]i/RhoA (显示 RHOA 抗体) pathway, which contributes to the acidity-induced epithelial-mesenchymal transition.

  2. The results show that acid-sensing ion channel 1 (显示 ACCN2 抗体), acid-sensing ion channel 2 (显示 ACCN1 抗体), and acid-sensing ion channel 3 are expressed in A549 cells at the messenger RNA and protein levels, and acid-sensing ion channel (显示 ACCN2 抗体)-like currents were elicited by extracellular acid stimuli.

  3. Blocking ASIC3 in interneurons from temporal lobe epilepsy patients decreased the frequency of action potential firing.

  4. These findings open new perspectives on the roles of ASIC3 in the absence of tissue pH variation, as well as on the contribution of those channels to lipid-mediated signaling.

  5. Sea (显示 Slc25a1 抗体) anemone peptide with uncommon beta-hairpin structure inhibits acid-sensing ion channel 3 (ASIC3) and reveals analgesic activity.

  6. Experiments with Asic3 inhibitors show that Asic3 inhibition leads to loss of pressure-induced vasodilation due to pressure detection failure rather than endothelial mechanisms.

  7. The highly proton sensitive ASIC3 channels are predominantly distributed in peripheral sensory neurons, correlating with their roles in multimodal sensory perception, including nociception, mechanosensation, and chemosensation.

  8. CAR and ASIC3 co-immunoprecipitate only when co-expressed with PSD-95 (显示 DLG4 抗体).

  9. Lignan from thyme possesses inhibitory effect on ASIC3 channel current.

  10. A mechanism of induction of ASIC-3 expression relevant to AR was suggested by the finding that eosinophil peroxidase (EPO (显示 EPX 抗体)), acting via ERK1/2, induced the expression of ASIC-3 in epithelial cells.

Mouse (Murine) Amiloride-Sensitive Cation Channel 3 (ACCN3) interaction partners

  1. acid-sensing ion channel 3, activated by concomitant acid and certain pruritogens, constitute a novel signaling pathway that counteracts itch tachyphylaxis to successive pruritogenic stimulation.

  2. a small conopeptide of only four amino acids from the venom of Conus textile that strongly potentiated currents of ASIC3, which has a specific role in the pain pathway. This peptide, RPRFamide, belongs to the subgroup of cono-RFamides.

  3. High ASIC3 expression is associated with Bone Pain Induced by Multiple Myeloma.

  4. This study suggested that the macrophage- and neutrophil-produced IL1beta (显示 IL1B 抗体) in the muscles during I/R activates enhanced IL1r1 (显示 IL1RN 抗体) in muscle afferents increase expression of ASIC3 possibly via JNK (显示 MAPK8 抗体) activation.

  5. segmental analgesia of electroacupuncture-induced analgesia (EA) with lower intensity is partially mediated by ASIC3 receptor on Abeta (显示 APP 抗体)-fiber, whereas systemic analgesia induced by EA with higher intensity is more likely induced by TRPV1 (显示 TRPV1 抗体) receptor on Adelta- and C-fibers

  6. the potentiation of ASICs by quinine depends on the presence of the ASIC1a (显示 ACCN2 抗体), ASIC2a (显示 ACCN1 抗体) subunits, but not ASIC1b, ASIC3 subunits. Furthermore, we have determined the amino acids in ASIC1a (显示 ACCN2 抗体) that are involved in the modulation of ASICs by pHi.

  7. fatigue reduces pH in muscle that subsequently activates ASIC3 on macrophages to enhance hyperalgesia to muscle insult.

  8. ASIC3 is critical for scratching behavior and pathological changes in chronic itch.

  9. Data suggest that activation of acid-sensing ion channel 3 (ASIC3) on fibroblast-like synoviocytes (FLS) by acidic pH from an inflamed joint could limit synovial proliferation resulting in reduced inflammatory mediators and subsequent joint damage.

  10. we unraveled an important role of ASIC3 in regulating cardiac autonomic function, whereby loss of ASIC3 alters the normal physiological response to ischemic stimuli.

Amiloride-Sensitive Cation Channel 3 (ACCN3) 抗原简介

蛋白简介

This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with ACCN3

  • amiloride-sensitive cation channel 3 (ACCN3) 抗体
  • acid sensing ion channel subunit 3 (ASIC3) 抗体
  • acid sensing ion channel subunit 3 (Asic3) 抗体
  • acid-sensing (proton-gated) ion channel 3 (Asic3) 抗体
  • Accn3 抗体
  • AW742291 抗体
  • DRASIC 抗体
  • SLNAC1 抗体
  • TNAC1 抗体

Protein level used designations for ACCN3

amiloride-sensitive cation channel 3 , amiloride-sensitive cation channel 3-like , DRASIC , acid sensing ion channel 3 , acid-sensing ion channel 3 , dorsal root ASIC , proton gated cation channel DRASIC , amiloride-sensitive cation channel 3, testis , modulatory subunit of ASIC2a , neuronal amiloride-sensitive cation channel 3 , proton-gated cation channel subunit , testis sodium channel 1

GENE ID SPECIES
429486 Gallus gallus
100063408 Equus caballus
100350503 Oryctolagus cuniculus
100442058 Pongo abelii
286920 Rattus norvegicus
9311 Homo sapiens
171209 Mus musculus
482801 Canis lupus familiaris
789132 Bos taurus
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