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Promotes growth and fasciculation of neurites from cultured hippocampal neurons.
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Mammalian Monoclonal AMIGO1 Primary Antibody for ISt, IHC - ABIN1304529
Mandikian, Bocksteins, Parajuli, Bishop, Cerda, Shigemoto, Trimmer: Cell type-specific spatial and functional coupling between mammalian brain Kv2.1 K+ channels and ryanodine receptors. in The Journal of comparative neurology 2014
The AMIGO1-KCNB1 complex is involved in schizophrenia-related behavioral domains in mice.
Data show that AMIGO is a glycosylated protein widely expressed in the central nervous system (CNS), and can be found in neurons, astrocytes as well as oligodendrocytes.
AMIGO is a function-modulating auxiliary subunit for Kv2.1 (显示 KCNB1 抗体).
AMIGO1 is identified as a candidate gene for human schizophrenia and related psychiatric disorders.
Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain.
, alivin 2
, amphoterin induced gene and ORF (Amigo)
, amphoterin-induced protein 1
, amphoretin-induced gene and ORF
, transmembrane protein AMIGO
, amphoterin-induced gene and ORF
, AMIGO protein