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AMIGO1 抗体 (AA 554-574) (Biotin)

AMIGO1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S86-36 Biotin
产品编号 ABIN2483811
发货至: 中国
  • 抗原 See all AMIGO1 抗体
    AMIGO1 (Adhesion Molecule with Ig-Like Domain 1 (AMIGO1))
    抗原表位
    • 15
    • 12
    • 9
    • 8
    • 5
    • 5
    • 1
    AA 554-574
    适用
    • 40
    • 23
    • 8
    • 4
    • 4
    • 4
    宿主
    • 41
    • 14
    小鼠
    克隆类型
    • 41
    • 14
    单克隆
    标记
    • 13
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AMIGO1 antibody is conjugated to Biotin
    应用范围
    • 50
    • 19
    • 16
    • 14
    • 13
    • 13
    • 11
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    Detects ~60-80 kDa depending on maturity/glycosylation.
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Protein G Purified
    免疫原
    Fusion protein amino acids 554-574 (cytoplasmic C-terminus) of human AMIGO-1
    克隆位点
    S86-36
    亚型
    IgG1
    Top Product
    Discover our top product AMIGO1 Primary Antibody
  • 应用备注
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    说明

    1 μg/ml of ABIN2483811 was sufficient for detection of AMIGO-1 in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Conjugated antibodies should be stored at 4°C
  • 抗原
    AMIGO1 (Adhesion Molecule with Ig-Like Domain 1 (AMIGO1))
    别名
    AMIGO1 (AMIGO1 产品)
    别名
    A antibody, Amigo antibody, ali2 antibody, AMIGO antibody, AMIGO-1 antibody, adhesion molecule with Ig like domain 1 antibody, Amigo1 antibody, AMIGO1 antibody
    背景
    The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO1, AMIGO2 and AMIGO3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. They can form complexes with each other, but can also self-bind. AMIGO1, also designated Alivin2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO2 (Alivin1) is crucial for depolarization-dependent survival. Similar to AMIGO1 and AMIGO2, AMIGO3 (Alivin3) plays a role in hemophilic and/or heterophilic cell-cell interaction and signal transduction.
    基因ID
    57463
    NCBI登录号
    NP_065754
    UniProt
    Q86WK6
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