anti-Aconitase 2, Mitochondrial (ACO2) 抗体

The protein encoded by ACO2 belongs to the aconitase/IPM isomerase family. 再加上,我们可以发ACO2 试剂盒 (29)ACO2 蛋白 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ACO2 50 Q99798
ACO2 11429 Q99KI0
ACO2 79250 Q9ER34
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antibodies-online.cn销售最多的anti-ACO2 抗体

Showing 10 out of 116 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-ACO2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>721_B cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 IHC, WB <b>WB Suggested Anti-ACO2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Human heart 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 EIA, WB 0.4 mL Log in to see 6至8个工作日
$390.50
详细
非结合性 IHC (p), WB Western blot analysis of anti-ACO2 Pab (ABIN388648) in mouse heart(left) and 293 (right) tissue lysates (35 µg/lane). ACO2(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Perfused isolated rat heart whole tissue lysate was lysed with either A) 50 mM Tris-HCl, 150 mM NaCl, 1 mM EDTA, 1% NP-40, 0.1% SDS, 0.5% Na-deoxycholate, 1 mM Na3VO4, 20 mM NaF, 1 mM PMSF, 5 v/v % protease inhibitor cocktail or B) T-PER Tissue Protein Extraction Reagent [# 785101. Pierce], containing 1mM Na3VO4, 20 mM NaF, 5 v/v % protease inhibitor cocktail (Sigma). PVDF membrane was incubated in primary Ab [rabbit polyclonal antibody against ACO2 (Center) (ABIN388648). Solution: 1:1000 diluted in 5% NFM TBS-T 0,05 for overnight (15 hrs) at 4 °. Data courtesy of Boglarka Laczy M.D., Division of Cardiovascular Disease, Dept. of Medicine, University of Alabama at Birmingham. 400 μL Log in to see 10至11个工作日
$324.50
详细
非结合性 ICC, IF, IHC, IHC (p), WB Western Blot: Aconitase 2 Antibody [NBP1-90264] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells).Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells).Lane 3: PC12 cell lysate (Pheochromocytoma of rat adrenal medulla) Immunocytochemistry/Immunofluorescence: Aconitase 2 Antibody [NBP1-90264] - Staining of human cell line U-2 OS shows positivity in mitochondria. 0.1 mL Log in to see 10至13个工作日
$491.63
详细
非结合性 ICC, IF, IHC, IHC (p), IP, WB Western Blot: Aconitase 2 Antibody [NBP1-32781] - Sample (30 ug of whole cell lysate) A: 293T B: A431 7.5% SDS PAGE, antibody diluted at 1:10000. Immunocytochemistry/Immunofluorescence: Aconitase 2 Antibody [NBP1-32781] - Analysis of methanol-fixed HeLa, using antibody at 1:500 dilution. 0.1 mL Log in to see 7至9个工作日
$514.63
详细
山羊 非结合性 IHC, ELISA, WB (0.01µg/ml) staining of Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6至7个工作日
$358.02
详细
山羊 非结合性 ELISA, IHC, IHC (p), WB Immunohistochemistry-Paraffin: Aconitase 2 Antibody [NBP1-52014] - (3.8ug/ml) staining of paraffin embedded Human Breast. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Western Blot: Aconitase 2 Antibody [NBP1-52014] - (0.01ug/ml) staining of Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7至9个工作日
$485.88
详细
小鼠 非结合性 IF, IHC (p), WB 100 μL Log in to see 7至9个工作日
$507.83
详细
小鼠 非结合性 FACS, IF, WB 100 μL Log in to see 7至9个工作日
$507.83
详细

通过反应活性、应用领域、克隆类型和共轭标记 ACO2 抗体

特性 应用范围 宿主 克隆类型 标记
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Mouse (Murine)
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Rat (Rattus)
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引用最多的anti-ACO2 抗体

  1. Human Polyclonal ACO2 Primary Antibody for IHC (p), WB - ABIN388648 : OConnell, Gannon, Doran, Ohlendieck: Proteomic profiling reveals a severely perturbed protein expression pattern in aged skeletal muscle. in International journal of molecular medicine 2007 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal ACO2 Primary Antibody for EIA, WB - ABIN357262 : Geurts van Kessel, Westerveld, de Groot, Meera Khan, Hagemeijer: Regional localization of the genes coding for human ACO2, ARSA, and NAGA on chromosome 22. in Cytogenetics and cell genetics 1981 (PubMed)
    Show all 8 Pubmed References

  3. Cow (Bovine) Polyclonal ACO2 Primary Antibody for WB - ABIN2786627 : Yu, Costello, Feng, Franklin: Characterization of the mitochondrial aconitase promoter and the identification of transcription factor binding. in The Prostate 2006 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal ACO2 Primary Antibody for ICC, IF - ABIN4277666 : Cantu, Fulton, Drechsel, Patel: Mitochondrial aconitase knockdown attenuates paraquat-induced dopaminergic cell death via decreased cellular metabolism and release of iron and H₂O₂. in Journal of neurochemistry 2011 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal ACO2 Primary Antibody for ELISA - ABIN513071 : Lin, Brownsey, MacLeod: Regulation of mitochondrial aconitase by phosphorylation in diabetic rat heart. in Cellular and molecular life sciences : CMLS 2009 (PubMed)

  6. Human Polyclonal ACO2 Primary Antibody for ICC, IF - ABIN442737 : Tammineni, Anugula, Mohammed, Anjaneyulu, Larner, Sepuri: The import of the transcription factor STAT3 into mitochondria depends on GRIM-19, a component of the electron transport chain. in The Journal of biological chemistry 2013 (PubMed)

  7. Human Polyclonal ACO2 Primary Antibody for ELISA, IHC - ABIN4277665 : Bota, Davies: Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism. in Nature cell biology 2002 (PubMed)

  8. Cow (Bovine) Polyclonal ACO2 Primary Antibody for IHC, WB - ABIN2786628 : Scheving, Wittig, Heide, Albuquerque, Steger, Brandt, Tegeder: Protein S-nitrosylation and denitrosylation in the mouse spinal cord upon injury of the sciatic nerve. in Journal of proteomics 2012 (PubMed)

  9. Human Polyclonal ACO2 Primary Antibody for IHC (p), WB - ABIN391809 : Dey, Guha, Alam, Goyal, Bindu, Pal, Maity, Mitra, Bandyopadhyay: Malarial infection develops mitochondrial pathology and mitochondrial oxidative stress to promote hepatocyte apoptosis. in Free radical biology & medicine 2009 (PubMed)

更多抗ACO2的相互作用对抗体

Arabidopsis thaliana Aconitase 2, Mitochondrial (ACO2) interaction partners

  1. The identification of ACO1 (显示 ACO1 抗体), ACO2, and ACO3 in A. thaliana is reported, and it was demonstrated that, in plants, the cytosolic ACOs are not converted into iron regulatory proteins.

Human Aconitase 2, Mitochondrial (ACO2) interaction partners

  1. Results suggest that ACO2 activity is reduced in peripheral lymphocytes of subjects with Alzheimer's disease and mild cognitive impairment and correlates with antioxidant protection

  2. Our study shows that autosomal recessive ACO2 mutations can cause either isolated or syndromic optic neuropathy.

  3. immunofluorescence staining localized ACO2 to the human sperm mid-piece. By immunoblotting, we demonstrated that the level of ACO2 protein in asthenozoospermic samples was significantly decreased compared with that in normal fertile men

  4. Ogg1 (显示 OGG1 抗体) chaperoning of Aco-2 in preventing oxidant-mediated mtDNA damage and apoptosis may afford an innovative target for the molecular events underlying oxidant-induced toxicity.

  5. Hypoxia upregulates the gene expression of mitochondrial aconitase in prostate carcinoma cells

  6. Gastric cancer patients with lower ACO2 expression have a shorter survival time than those with higher ACO2 expression.

  7. Homozygosity mapping followed by whole-exome sequencing disclosed a Ser112Arg mutation in ACO2.

  8. these results suggest that p53 downregulation of mACON gene expression in human prostate carcinoma cells may not occur through the putative consensus p53 response elements found within the mACON promoter.

  9. Lon (显示 LONP1 抗体) protease selectively recognizes and degrades the oxidized, hydrophobic form of aconitase (显示 ACO1 抗体) after mild oxidative modification, but that severe oxidation results in aconitase (显示 ACO1 抗体) aggregation, which makes it a poor substrate for Lon (显示 LONP1 抗体).

  10. ACO2 is often deleted in colorectal cancer (显示 DCC 抗体) but is unlikely to be the true target of the deletions

Mouse (Murine) Aconitase 2, Mitochondrial (ACO2) interaction partners

  1. Activation of mitochondrial aconitase is acetylation-dependent.

  2. Ogg1 (显示 OGG1 抗体) chaperoning of Aco-2 in preventing oxidant-mediated mtDNA damage and apoptosis may afford an innovative target for the molecular events underlying oxidant-induced toxicity.

  3. IRP-1 (显示 ACO1 抗体),-2 are indispensable for regulation of mammalian iron homeostasis at the post-implantation stage of murine embryonic development

  4. aconitase activity can be regulated by at least two mechanisms: oxidation/reduction and phosphorylation/dephosphorylation

Pig (Porcine) Aconitase 2, Mitochondrial (ACO2) interaction partners

  1. study examined the sites and mechanisms of aconitase inactivation by peroxynitrite (ONOO-), a strong oxidant and nitrating agent readily formed from superoxide anion and nitric oxide generated by mitochondria

ACO2 抗原简介

蛋白简介

The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.

Gene names and symbols associated with ACO2

  • aconitase 2 (ACO2) 抗体
  • aconitase 2 S homeolog (aco2.S) 抗体
  • aconitate hydratase, mitochondrial (Bm1_07420) 抗体
  • aconitase, mitochondrial (aco2) 抗体
  • mitochondrial aconitate hydratase (ach1) 抗体
  • aconitase 2 (aco2) 抗体
  • aconitase 2, mitochondrial (Aco2) 抗体
  • aconitase 2 (Aco2) 抗体
  • aconitase 2, mitochondrial (aco2) 抗体
  • Probable aconitate hydratase, mitochondrial (aco-2) 抗体
  • Aco-2 抗体
  • Aco3 抗体
  • aconitase 2 抗体
  • ACONM 抗体
  • cb1017 抗体
  • D10Wsu183e 抗体
  • DDBDRAFT_0206187 抗体
  • DDBDRAFT_0230168 抗体
  • DDB_0206187 抗体
  • DDB_0230168 抗体
  • F10M23.310 抗体
  • F10M23_310 抗体
  • ICRD 抗体
  • wu:fa10e03 抗体
  • wu:fb69g04 抗体
  • wu:fc20c11 抗体

Protein level used designations for ACO2

aconitate hydratase, mitochondrial , mitochondrial aconitate hydratase , aconitase 2, mitochondrial , aconitate hydratase, mitochondrial-like , citrate hydro-lyase , mitochondrial aconitase (nuclear aco2 gene) , heart aconitase

GENE ID SPECIES
374009 Gallus gallus
444692 Xenopus laevis
6096411 Brugia malayi
8621690 Dictyostelium discoideum AX4
9617127 Volvox carteri f. nagariensis
100444223 Pongo abelii
496933 Xenopus (Silurana) tropicalis
707441 Macaca mulatta
828805 Arabidopsis thaliana
100352714 Oryctolagus cuniculus
100389367 Callithrix jacchus
100568244 Anolis carolinensis
100598337 Nomascus leucogenys
50 Homo sapiens
11429 Mus musculus
79250 Rattus norvegicus
396999 Sus scrofa
280976 Bos taurus
474487 Canis lupus familiaris
322670 Danio rerio
176121 Caenorhabditis elegans
anti-ACO2 (ACO2) 抗体 精选生产商
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