ACO2 产品
(Aconitase 2, Mitochondrial (ACO2))
Categories
The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008].
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Featured ACO2 Categories
ACO2 抗体
High quality antibodies with extensive validation data.
ACO2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
ACO2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ACO2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (7)
Cat. No.
ABIN1678537
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN7265379
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Pig, Rat
Application
WB, ELISA, IHC
Validations
- (4)
Cat. No.
ABIN571125
Quantity
100 μg
Datasheet
Datasheet
Recommended ACO2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964545
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964544
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964543
Quantity
96 tests
Datasheet
Datasheet
Recommended ACO2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305654
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305656
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN7320070
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our ACO2 Products
: "Oxidative stress and mitochondrial dynamics malfunction are linked in Pelizaeus-Merzbacher disease." in: Brain pathology (Zurich, Switzerland), (2017) (PubMed).: "Mitoferrin modulates iron toxicity in a Drosophila model of Friedreich?s ataxia." in: Free radical biology & medicine, Vol. 85, pp. 71-82, (2015) (PubMed).
: "Akt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial-mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells." in: Oncogene, Vol. 34, Issue 5, pp. 546-57, (2015) (PubMed).
: "Reduced synaptic vesicle protein degradation at lysosomes curbs TBC1D24/sky-induced neurodegeneration." in: The Journal of cell biology, Vol. 207, Issue 4, pp. 453-62, (2014) (PubMed).
: "STED super-resolution microscopy of clinical paraffin-embedded human rectal cancer tissue." in: PLoS ONE, Vol. 9, Issue 7, pp. e101563, (2014) (PubMed).
: "Proteomic profiling and pathway analysis of the response of rat renal proximal convoluted tubules to metabolic acidosis." in: American journal of physiology. Renal physiology, Vol. 305, Issue 5, pp. F628-40, (2013) (PubMed).
: "Response of the mitochondrial proteome of rat renal proximal convoluted tubules to chronic metabolic acidosis." in: American journal of physiology. Renal physiology, Vol. 304, Issue 2, pp. F145-55, (2013) (PubMed).
: "The import of the transcription factor STAT3 into mitochondria depends on GRIM-19, a component of the electron transport chain." in: The Journal of biological chemistry, Vol. 288, Issue 7, pp. 4723-32, (2013) (PubMed).
: "Protein S-nitrosylation and denitrosylation in the mouse spinal cord upon injury of the sciatic nerve." in: Journal of proteomics, Vol. 75, Issue 13, pp. 3987-4004, (2012) (PubMed).
: "Mitochondrial aconitase knockdown attenuates paraquat-induced dopaminergic cell death via decreased cellular metabolism and release of iron and H₂O₂." in: Journal of neurochemistry, Vol. 118, Issue 1, pp. 79-92, (2011) (PubMed).
Synonyms and alternative names related to ACO2
aconitase 2 (ACO2), aconitase 2 S homeolog (aco2.S), aconitate hydratase, mitochondrial (Bm1_07420), aconitase, mitochondrial (aco2), mitochondrial aconitate hydratase (ach1), aconitase 2 (aco2), aconitase 2, mitochondrial (Aco2), aconitase 2 (Aco2), aconitase 2, mitochondrial (aco2), Probable aconitate hydratase, mitochondrial (aco-2), Aco-2, Aco3, aconitase 2, ACONM, cb1017, D10Wsu183e, DDBDRAFT_0206187, DDBDRAFT_0230168, DDB_0206187, DDB_0230168, F10M23.310, F10M23_310, ICRD, wu:fa10e03, wu:fb69g04, wu:fc20c11Protein level used designations for ACO2
- aconitate hydratase, mitochondrial
- mitochondrial aconitate hydratase
- aconitase 2, mitochondrial
- aconitate hydratase, mitochondrial-like
- citrate hydro-lyase
- mitochondrial aconitase (nuclear aco2 gene)
- heart aconitase
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