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ACMSD 产品

(Aminocarboxymuconate Semialdehyde Decarboxylase (ACMSD))
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase\; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM, Oct 2004].

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Featured ACMSD Categories

ACMSD 抗体

High quality antibodies with extensive validation data.

ACMSD ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ACMSD 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ACMSD 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN7142142
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
  • (2)
Cat. No. ABIN566800
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN2856426
Quantity 100 μL
Datasheet Datasheet

Recommended ACMSD ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1118709
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1118710
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1118712
Quantity 96 tests
Datasheet Datasheet

Recommended ACMSD 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305646
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305648
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7422079
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ACMSD Products

Palzer, Bader, Angel, Witzel, Blaser, McNeil, Wandersee, Leu, Lengner, Cho, Welch, Kirkland, Meyer, Meyer-Ficca: "Alpha-Amino-Beta-Carboxy-Muconate-Semialdehyde Decarboxylase Controls Dietary Niacin Requirements for NAD+ Synthesis." in: Cell reports, Vol. 25, Issue 5, pp. 1359-1370.e4, (2018) (PubMed).

Guillemin, Cullen, Lim, Smythe, Garner, Kapoor, Takikawa, Brew: "Characterization of the kynurenine pathway in human neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 47, pp. 12884-92, (2007) (PubMed).

Synonyms and alternative names related to ACMSD

aminocarboxymuconate semialdehyde decarboxylase (ACMSD), aminocarboxymuconate semialdehyde decarboxylase (acmsd), aminocarboxymuconate semialdehyde decarboxylase S homeolog (acmsd.S), amino carboxymuconate semialdehyde decarboxylase (Acmsd), aminocarboxymuconate semialdehyde decarboxylase (Acmsd), ACMSD, zgc:162888

Protein level used designations for ACMSD

  • aminocarboxymuconate semialdehyde decarboxylase
  • 2-amino-3-carboxylmuconate-6-semialdehyde decarboxylase
  • 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
  • 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase-like
  • picolinate carboxylase
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