(4 references)-
- 抗原 See all ACO2 抗体
- ACO2 (Aconitase 2, Mitochondrial (ACO2))
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抗原表位
- Center
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ACO2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects ACO2 at center.
- 纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- 免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the central region of human Aconitase.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product ACO2 Primary Antibody
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anti-Aconitase 2, Mitochondrial (ACO2) (AA 501-780) antibody
ACO2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 2, Mitochondrial (ACO2) antibodyACO2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Aconitase 2, Mitochondrial (ACO2) (AA 541-555) antibodyVerified ACO2 适用: 人, 大鼠, 小鼠, Pig WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Aconitase 2, Mitochondrial (ACO2) (AA 438-467) antibodyACO2 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB9338 unconjugated
anti-Aconitase 2, Mitochondrial (ACO2) (AA 452-676) antibodyACO2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 2, Mitochondrial (ACO2) antibodyACO2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 2, Mitochondrial (ACO2) (AA 544-693) antibodyACO2 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aconitase 2, Mitochondrial (ACO2) (AA 294-325) antibodyACO2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14646 unconjugated
anti-Aconitase 2, Mitochondrial (ACO2) antibodyACO2 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 8H4 unconjugated Recombinant Antibody
anti-Aconitase 2, Mitochondrial (ACO2) (Internal Region) antibodyVerified ACO2 适用: 人 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
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ELISA 1: 1,000. Western blot 1: 100 - 1: 500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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: "Akt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial-mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells." in: Oncogene, Vol. 34, Issue 5, pp. 546-57, (2015) (PubMed).
: "Reduced synaptic vesicle protein degradation at lysosomes curbs TBC1D24/sky-induced neurodegeneration." in: The Journal of cell biology, Vol. 207, Issue 4, pp. 453-62, (2014) (PubMed).
: "Indomethacin, a non-steroidal anti-inflammatory drug, develops gastropathy by inducing reactive oxygen species-mediated mitochondrial pathology and associated apoptosis in gastric mucosa: a novel ..." in: The Journal of biological chemistry, Vol. 284, Issue 5, pp. 3058-68, (2009) (PubMed).
: "Proteomic profiling reveals a severely perturbed protein expression pattern in aged skeletal muscle." in: International journal of molecular medicine, Vol. 20, Issue 2, pp. 145-53, (2007) (PubMed).
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: "Akt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial-mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells." in: Oncogene, Vol. 34, Issue 5, pp. 546-57, (2015) (PubMed).
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- 抗原
- ACO2 (Aconitase 2, Mitochondrial (ACO2))
- 别名
- ACO2 (ACO2 产品)
- 别名
- DDBDRAFT_0206187 antibody, DDBDRAFT_0230168 antibody, DDB_0206187 antibody, DDB_0230168 antibody, aconitase 2 antibody, F10M23.310 antibody, F10M23_310 antibody, ACONM antibody, ICRD antibody, Aco-2 antibody, Aco3 antibody, D10Wsu183e antibody, cb1017 antibody, wu:fa10e03 antibody, wu:fb69g04 antibody, wu:fc20c11 antibody, aconitase 2 antibody, aconitase 2 S homeolog antibody, aconitate hydratase, mitochondrial antibody, aconitase, mitochondrial antibody, mitochondrial aconitate hydratase antibody, aconitase 2, mitochondrial antibody, Probable aconitate hydratase, mitochondrial antibody, ACO2 antibody, aco2.S antibody, Bm1_07420 antibody, aco2 antibody, ach1 antibody, Aco2 antibody, aco-2 antibody
- 背景
- ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.Synonyms: Aconitase 2, Aconitate hydratase mitochondrial
- 分子量
- 85425 Da.
- 基因ID
- 50, 9606
- UniProt
- Q99798
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