anti-A Kinase (PRKA) Anchor Protein 8 (AKAP8) 抗体

AKAP8 encodes a member of the A-kinase anchor protein family. 再加上,我们可以发AKAP8 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
AKAP8 10270 O43823
AKAP8 56399 Q9DBR0
AKAP8 116633 Q63014
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antibodies-online.cn销售最多的anti-AKAP8 抗体

Showing 10 out of 105 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-AKAP8 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: 293T cell lysate AKAP8 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells 100 μL 2至3个工作日
$289.00
详细
Cow 非结合性 WB WB Suggested Anti-AKAP8 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  293T cell lysate AKAP8 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells 100 μL 2至3个工作日
$289.00
详细
Cow 非结合性 WB WB Suggested Anti-AKAP8 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  HepG2 cell lysate AKAP8 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells 100 μL 2至3个工作日
$289.00
详细
山羊 非结合性 ELISA, WB ABIN185207 staining (1µg/ml) of Human Liver lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg 6至7个工作日
$429.84
详细
非结合性 IC, IF, WB Immunofluorescent analysis of AKAP8 staining in Jurkat cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of AKAP8 expression in HepG2 (A), Jurkat (B), mouse kidney (C), rat kidney (D) whole cell lysates. 200 μL 13至14个工作日
$487.50
详细
非结合性 IF, IHC, ELISA, WB Western blot analysis of extracts from mouse heart/Jurkat cells, using AKAP8 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human heart tissue, using AKAP8 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2至3个工作日
$302.50
详细
非结合性 ELISA, ICC, IF, IHC, WB ABIN6266711 at 1/100 staining human kidney tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis on various tissue lysate using AKAP8 Antibody 100 μL 11至12个工作日
$390.77
详细
小鼠 非结合性 ELISA, IF, IHC, IHC (p), WB 100 μg 11至14个工作日
$537.17
详细
非结合性 ELISA, IF, IHC, WB Western Blot (WB) analysis of specific cells using AKAP 95 Polyclonal Antibody. 100 μL Available
$363.46
详细
非结合性 IHC, WB Western blot analysis of extracts of various cells, using AKAP8 antibody. Immunohistochemistry of paraffin-embedded human esophagus using AKAP8 antibody. 100 μL 11至13个工作日
$366.77
详细

引用最多的anti-AKAP8 抗体

  1. Human Polyclonal AKAP8 Primary Antibody for FACS, ICC - ABIN4278933 : Li, Kao, Garcia, Shabanowitz, Hunt, Qin, Phelan, Lazar: A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity. in Genes & development 2006 (PubMed)

  2. Mouse (Murine) Polyclonal AKAP8 Primary Antibody for ELISA, WB - ABIN250209 : Eide, Coghlan, Orstavik, Holsve, Solberg, Skâlhegg, Lamb, Langeberg, Fernandez, Scott, Jahnsen, Taskén: Molecular cloning, chromosomal localization, and cell cycle-dependent subcellular distribution of the A-kinase anchoring protein, AKAP95. in Experimental cell research 1998 (PubMed)

更多抗AKAP8的相互作用对抗体

Human A Kinase (PRKA) Anchor Protein 8 (AKAP8) interaction partners

  1. The PKA-binding domain of AKAP8 and the C-terminal domain of DPY30, also called Dpy-30 motif, are crucial for the interaction between these proteins. AKAP8 interacts with DPY30 and the RII alpha regulatory subunit of PKA both in the interphase and in mitotic cells. A single amino acid substitution in DPY30 L69D affects its dimerization and completely abolishes its interaction with AKAP8.

  2. These results establish AKAP95 as a mostly positive regulator of pre-mRNA splicing and a possible integrator of transcription and splicing regulation.

  3. Results suggest that ALK generated by alternative transcription Initiation induces chromatin structural changes and heterochromatinization through phosphorylation of AKAP8 in the nucleus.

  4. Using a BioID proximity-based proteomic screen, we identify the nuclear pore complex protein TPR as a novel AKAP95 binding partner. We show interaction between AKAP95 and TPR in mitosis, and an AKAP95-dependent enrichment of TPR in the spindle microtubule area in metaphase, then later in the spindle midzone area.

  5. Report expression of connexin 43 in ovarian cancer cells in G1/S phase.

  6. The data indicate that AKAP95 is a novel nucleolus-associated protein with a regulatory role on rRNA production.

  7. Gene dosage at 19p13.12, and AKAP8 and/or AKAP8L in particular, play an important role in modulation of head size and may contribute to autism risk.

  8. These results suggest that AKAP8 is involved in the regulation of chromatin structural changes through nuclear tyrosine phosphorylation.

  9. Ectopic AKAP95 stimulates expression of a chromosomal reporter gene in synergy with MLL1 or MLL2, whereas AKAP95 depletion impairs retinoic acid-mediated gene induction in embryonic stem cells

  10. AMY-1 interacts with S-AKAP84 and this protein in the cytoplasm and the nucleus, respectively, and inhibits cAMP-dependent protein kinase activity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex.

  11. role of AKAP95 in DNA replication by providing a scaffold for MCM2

  12. AKAP95 is a potential carrier protein for active caspase 3 from the cytoplasm into the nuclei in apoptotic cells.

Mouse (Murine) A Kinase (PRKA) Anchor Protein 8 (AKAP8) interaction partners

  1. This study showed an increase in the level of global DNA methylation starting in oocytes with diameters around 60 microm, increases in histone h4, and decreases in AKAP95.

  2. a specific role for A kinase-anchoring protein 95 in suppressing the expression of the gene encoding tumor necrosis factor-alpha, which involved phosphorylation of p105 (also known as Nfkb1) by PKA

AKAP8 抗原简介

蛋白简介

This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9.

Gene names and symbols associated with AKAP8

  • A-kinase anchoring protein 8 (AKAP8) 抗体
  • A-kinase anchoring protein 8 (akap8) 抗体
  • A kinase (PRKA) anchor protein 8 (Akap8) 抗体
  • A-kinase anchoring protein 8 (Akap8) 抗体
  • 1200016A02Rik 抗体
  • AA673585 抗体
  • AKAP-8 抗体
  • AKAP-95 抗体
  • AKAP8 抗体
  • AKAP 95 抗体
  • Akap95 抗体
  • AU015639 抗体
  • MGC108502 抗体

Protein level used designations for AKAP8

A kinase (PRKA) anchor protein 8 , A-kinase anchor protein 8 , A-kinase anchor protein 8-like , a-kinase anchor protein 8-like , A-kinase anchor protein, 95kDa , A kinase anchor protein 8 , A kinase anchor protein 95 , A-kinase anchor protein 95 kDa , AKAP 95 , AKAP-8 , protein kinase A-anchoring protein 95

GENE ID SPECIES
426167 Gallus gallus
613077 Xenopus (Silurana) tropicalis
748028 Pan troglodytes
100349200 Oryctolagus cuniculus
100406198 Callithrix jacchus
100457181 Pongo abelii
10270 Homo sapiens
56399 Mus musculus
116633 Rattus norvegicus
522905 Bos taurus
474362 Canis lupus familiaris
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