(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8))
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined\; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes. [provided by RefSeq, Jul 2008].
Hogue, Liu, Ling: "Identification and characterization of a mammalian mitochondrial ATP-binding cassette membrane protein." in: Journal of molecular biology, Vol. 285, Issue 1, pp. 379-89, (1999) (PubMed).
Aliases for ABCB8 抗体
ATP binding cassette subfamily B member 8 (ABCB8) 抗体 ATP-binding cassette, sub-family B (MDR/TAP), member 8 (Abcb8) 抗体 ATP binding cassette subfamily B member 8 (Abcb8) 抗体 ATP-binding cassette, sub-family B (MDR/TAP), member 8 (abcb8) 抗体 ATP binding cassette subfamily B member 8 (abcb8) 抗体 4833412N02Rik 抗体 AA409895 抗体 ABCB8 抗体 EST328128 抗体 M-ABC1 抗体 MABC1 抗体 zgc:113037 抗体