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ABCB8 抗体 (Internal Region)

ABCB8 适用: 人, 兔 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5596884
发货至: 中国
  • 抗原 See all ABCB8 抗体
    ABCB8 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8))
    抗原表位
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 20
    • 10
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    人, 兔
    宿主
    • 21
    • 1
    克隆类型
    • 22
    多克隆
    标记
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABCB8 antibody is un-conjugated
    应用范围
    • 13
    • 7
    • 6
    • 3
    • 2
    Western Blotting (WB), ELISA
    交叉反应 (详细)
    A BLAST analysis was used to suggest cross-reactivity with ABCB8 from human, mouse, and rat based on a 100% homology with the immunizing sequence. Reactivity against homologues from other sources is not known. The antibody detects ABCB8 in cell lysates.
    纯化方法
    Anti-ABCB8 Antibody was prepared from monospecific, delipidated and defibrinated antiserum, with addition of sodium azide to 0.01%.
    免疫原

    Immunogen: ABCB8 was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a internal portion of human ABCB8.

    Immunogen Type: Peptide

    亚型
    IgG
    Top Product
    Discover our top product ABCB8 Primary Antibody
  • 应用备注

    Application Note: Anti-ABCB8 antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect band approximately 79.9 kDa in size corresponding to ABCB8 by western blotting in the appropriate cell lysate or extract.

    Western Blot Dilution: 1:250-1:500

    ELISA Dilution: 1:20,000-1:50,000

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    80 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    ABCB8 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8))
    别名
    ABCB8 (ABCB8 产品)
    别名
    EST328128 antibody, M-ABC1 antibody, MABC1 antibody, 4833412N02Rik antibody, AA409895 antibody, ABCB8 antibody, zgc:113037 antibody, ATP binding cassette subfamily B member 8 antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 8 antibody, ABCB8 antibody, Abcb8 antibody, abcb8 antibody
    背景

    Synonyms: ATP-binding cassette sub-family B member 8 mitochondrial, Mitochondrial ATP-binding cassette 1, M-ABC1, ABCB8

    Background: This antibody is designed, produced, and validated as part of a collaboration between Rockland and the National Cancer Institute (NCI) and is suitable for Cancer Research and drug resistance. ABCB8 is designed, produced, and validated as part of a collaboration between Rockland and the National Cancer Institute (NCI). It has been found that ABC transporters are involved in mulitdrug resistance through their ability to contol the presence of drugs in cells. Multidrug resistance is currently being looked at in particular reference to cancer that is resistant to treatment. ABCB8 seems to have particulalrly high resistance rates in renal cancer and cancer of the central nervous system. Another significant aspect of ABCB8 is that it is a mitochondrial transporter. There are very few ABC transporters localized to the mitochondria which implies information about them could be extremely important. ABCB8 may also be localized to other parts of the cell which are yet to be determined. Anti-ABCB8 antibody is ideal for researchers nterested in Cancer Research and drug resistance.

    Gene Name: ABCB8

    基因ID
    11194
    UniProt
    Q9NUT2
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