WNT1 蛋白 (WNT1)产品概述

Full name:
Wingless-Type MMTV Integration Site Family, Member 1 蛋白 (WNT1)
在www.antibodies-online.cn可供9 Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) 蛋白的7不同的供货商。 再加上,我们可以发WNT1 抗体 (113)WNT1 试剂盒 (16)和数多这个蛋白质的别的产品。 总共147 WNT1产品已列进来了。
别名:
BMND16, Int-1, Int1, OI15, sb:eu647, sw, swaying, WNT-1, WNT1, wnt1-a, Xint-1, Xwnt1, zgc:194464, zgc:194478
列出全部蛋白 基因 基因ID UniProt
小鼠 WNT1 WNT1 22408 P04426
WNT1 7471 P04628
大鼠 WNT1 WNT1 24881  

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引用最多的WNT1 蛋白

  1. Human WNT1 Protein expressed in Escherichia coli (E. coli) - ABIN413893 : Tawk, Makoukji, Belle, Fonte, Trousson, Hawkins, Li, Ghandour, Schumacher, Massaad: Wnt/beta-catenin signaling is an essential and direct driver of myelin gene expression and myelinogenesis. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 (PubMed)
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Xenopus laevis Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) interaction partners

  1. maternal Wnt (显示 WNT2 蛋白)/STOP signaling, but not beta-catenin (显示 CTNNB1 蛋白) signaling, has a role in cleavage after fertilization and cell cycle progression

  2. sfrp1 (显示 SFRP1 蛋白) promotes cardiomyocyte differentiation in Xenopus via negative-feedback regulation of Wnt (显示 WNT2 蛋白) signalling.

  3. analysis of differential role of Axin (显示 AXIN1 蛋白) RGS (显示 PITX2 蛋白) domain function in Wnt (显示 WNT2 蛋白) signaling during anteroposterior patterning and maternal axis formation

  4. Data show taht combined Wnt (显示 WNT2 蛋白) and Nodal signaling synergistically activates transcription of Spemann organizer genes.

  5. The authors propose that these dual functions of DP1 (显示 TFDP1 蛋白) can promote and stabilize biphasic Wnt (显示 WNT2 蛋白)-on and Wnt (显示 WNT2 蛋白)-off states in response to a gradual gradient of Wnt (显示 WNT2 蛋白)/beta-catenin (显示 CTNNB1 蛋白) signalling to determine differential cell fates.

Mouse (Murine) Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) interaction partners

  1. Results demonstrated functional differences in the molecular mechanisms downstream of Wnt1 function in the diencephalon, in relation to the spinal cord. Wnt1 signal determines the patterning of the diencephalic dorso-ventral axis

  2. Data show that both transgenic Wnt1-cre and P0-cre are similarly effective in deleting beta-catenin (显示 CTNNB1 蛋白) in the neural crest.

  3. data suggest that WNT1-related osteogenesis imperfecta (显示 COL1A2 蛋白) and osteoporosis are caused in part by decreased mTORC1-dependent osteoblast function resulting from loss of WNT1 signaling in osteocytes.

  4. Administration of EET alters Wnt1, NOV (显示 NOV 蛋白), and HO-1 (显示 HMOX1 蛋白) signaling to prevent obesity-induced cardiomyopathy in obese mice.

  5. Data indicate that Wnt1 proto-oncogene (显示 RAB1A 蛋白) protein (WNT1) is the direct target of microRNA miR (显示 MLXIP 蛋白)-34a in dendritic cell (DC).

  6. In order to evaluate the function of IFT88 (显示 IFT88 蛋白) in regulating craniofacial development, we generated Wnt1-Cre;Ift88fl/fl mice to eliminate Ift88 (显示 IFT88 蛋白) specifically in cranial neural crest (CNC) cells. Wnt1-Cre;Ift88fl/flpups died at birth due to severe craniofacial defects including bilateral cleft lip and palate and tongue agenesis, following the loss of the primary cilia in the CNC-derived palatal mesenchyme

  7. Wnt (显示 WNT2 蛋白), Eda (显示 EDA 蛋白), and Shh (显示 SHH 蛋白) have roles in touch dome Merkel cell development

  8. The data obtained from the 14-3-3epsilon/14-3-3zeta (显示 YWHAZ 蛋白)/Wnt1-Cre mice strongly indicate the importance of 14-3-3 (显示 YWHAQ 蛋白) proteins in the development of melanocyte lineages.

  9. High WNT1 promoted stem-ness characteristics and metastasis potential in sphere-forming liver cancer stem cells.

  10. Decreased expressions of Wnt1 and Wnt5a (显示 WNT5A 蛋白).

Human Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) interaction partners

  1. High WNT1 expression is associated with glioma cell invasion.

  2. bone formation is under the control of WNT1 produced by osteocytes, the cells that reside deep in the bone matrix and form dendritic networks.

  3. Knocking down of Wnt-1 by siRNA had the similar effect of miRNA-148a overexpression on cell migration and invasion in lung cancer cells.

  4. High WNT1 expression is associated with Lung Adenocarcinoma Progression.

  5. WNT1 overexpression is associated with Breast Cancer Invasion and Metastasis.

  6. PKA signaling is pivotal in pigmentation process itself in cultured melanoma cells, while the importance of Wnt (显示 WNT2 蛋白)/beta-catenin (显示 CTNNB1 蛋白) signaling should be emphasized in the context of development and differentiation

  7. Patients with WNT1 mutation-related osteoporosis respond to teriparatide treatment.

  8. High WNT1 expression is associated with osteosarcoma.

  9. These results suggest that alphaTAT1-mediated Wnt1 expression via microtubule acetylation is important for colon cancer progression.

  10. Upregulation of WNT (显示 WNT2 蛋白) is associated with prostate cancer.

Cow (Bovine) Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) interaction partners

  1. Data indicate that Wnt-1 protein is present in postdevelopmental endothelial cells where it associates with cytoskeletal elements and may retain function as a tissue polarity gene.

Zebrafish Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) interaction partners

  1. analysis of differential role of Axin (显示 AXIN1 蛋白) RGS (显示 PITX2 蛋白) domain function in Wnt (显示 WNT2 蛋白) signaling during anteroposterior patterning and maternal axis formation

  2. Rspo1-Wnt-VegfC-Vegfr3 signaling plays a crucial role as an endothelial-autonomous permissive cue for developmental angiogenesis.

  3. wnt1 and wnt10b (显示 WNT10B 蛋白) are required to maintain threshold levels of Pax2.1 and Fgf8 (显示 FGF8 蛋白) at the midbrain-hindbrain boundary.

  4. novel role for Wnt (显示 WNT2 蛋白)/beta-catenin (显示 CTNNB1 蛋白) signalling in determining endocardial cell fate

  5. In zebrafish embryos lacking Wnt3a (显示 WNT3A 蛋白), Wnt1 and Wnt10b (显示 WNT10B 蛋白), the expression of engrailed orthologs, pax2a and fgf8 (显示 FGF8 蛋白) is not maintained after mid-somitogenesis

  6. two Dvl (显示 DVL2 蛋白)-associated paralogs, Dpr1 (显示 DACT1 蛋白) and Dpr2 (显示 DACT2 蛋白), participate in distinct Wnt (显示 WNT2 蛋白)-dependent developmental processes

  7. Wnt (显示 WNT2 蛋白)/Axin (显示 AXIN1 蛋白)/beta-catenin (显示 CTNNB1 蛋白) pathway has a role in ventral CNS development

  8. The boundary and roof plate expression of wnt1 each contribute to upregulation of proneural and delta gene expression and neurogenesis in non-boundary regions.

  9. Epistatic analyses suggest a possible genetic interaction between Wnt (显示 WNT2 蛋白)/beta-catenin (显示 CTNNB1 蛋白) and Myostatin (显示 MSTN 蛋白) in regulation of slow and fast twitch muscle myofibrillogenesis

蛋白简介WNT1

蛋白简介

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.

Alternative names and synonyms associated with WNT1

  • wingless-type MMTV integration site family, member 1 (WNT1)
  • wingless-type MMTV integration site family, member 1 (wnt1)
  • wingless-related MMTV integration site 1 (Wnt1)
  • wingless-type MMTV integration site family, member 1 (Wnt1)
  • wingless-type MMTV integration site family, member 1 (WNT-1)
  • BMND16 蛋白
  • Int-1 蛋白
  • Int1 蛋白
  • OI15 蛋白
  • sb:eu647 蛋白
  • sw 蛋白
  • swaying 蛋白
  • WNT-1 蛋白
  • WNT1 蛋白
  • wnt1-a 蛋白
  • Xint-1 蛋白
  • Xwnt1 蛋白
  • zgc:194464 蛋白
  • zgc:194478 蛋白

Protein level used designations for WNT1

XWnt-1 , protein Wnt-1 , proto-oncogene Int-1 , proto-oncogene Wnt-1 , proto-oncogene protein Wnt-1 , proto-oncogene Int-1 homolog , wingless-type MMTV integration site family, member 1 (oncogene INT1) , Wingless-type MMTV integration site 1 homolog , Wingless-type MMTV integration site 1, homolog , wingless-related MMTV integration site 1 , murine mammary tumor virus integration site , etID22400.23 , wingless-type MMTV integration site family member 1

GENE ID SPECIES
100058859 Equus caballus
373578 Xenopus laevis
22408 Mus musculus
7471 Homo sapiens
24881 Rattus norvegicus
486560 Canis lupus familiaris
540662 Bos taurus
30128 Danio rerio
396160 Gallus gallus
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