anti-牛 VAV1 抗体 for Western Blotting

Recommended VAV1 Antibody (supplied by: Log in to see )

抗原
Vav 1 Oncogene (VAV1) 抗体
  • VAV
  • Vav
  • vav-T
  • vav 1 guanine nucleotide exchange factor
  • vav 1 oncogene
  • VAV1
  • Vav1
  • vav1
抗原表位
Middle Region
37
25
23
21
15
10
9
8
6
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
适用
牛, 犬, 马, 人, 小鼠, 猪, 兔, 大鼠
184
75
72
3
3
2
2
1
1
宿主

134
51
克隆类型
多克隆
标记
This VAV1 antibody is un-conjugated
5
5
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
应用范围
Western Blotting (WB)
157
71
26
23
14
14
11
6
3
1
1
1
1
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产品编号 ABIN2792554
$ 289.00
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN229275 WB Rabbit IgG AA 581-596 Log in to see Polyclonal

General

抗原 Vav 1 Oncogene (VAV1) 抗体
抗原表位 Middle Region
(37), (25), (23), (21), (15), (10), (9), (8), (6), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
适用 牛, 犬, 马, 人, 小鼠, 猪, 兔, 大鼠
(184), (75), (72), (3), (3), (2), (2), (1), (1)
宿主
(134), (51)
克隆类型
多克隆
标记 This VAV1 antibody is un-conjugated
(5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Western Blotting (WB)
(157), (71), (26), (23), (14), (14), (11), (6), (3), (1), (1), (1), (1)
Pubmed 找到1个引用
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VAV1抗体详情

VAV1目标详情 使用细节 贮存及处理 References for anti-VAV1 antibody (ABIN2792554) 图像
序列 RDRSELSLKE GDIIKILNKK GQQGWWRGEI YGRVGWFPAN YVEEDYSEYC
交叉反应 牛, 犬, 人, 小鼠, 大鼠
预测反应 Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 90%, Rat: 92%
产品特性 This is a rabbit polyclonal antibody against VAV1. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
免疫原 The immunogen is a synthetic peptide directed towards the middle region of human VAV1

VAV1目标详情

VAV1抗体详情 使用细节 贮存及处理 References for anti-VAV1 antibody (ABIN2792554) 图像 回页首
抗原
别名 VAV1 (VAV1 Antibody 摘要)
背景 This protein is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: VAV
Protein Interaction Partner: UBC, CD28, ERBB3, ERBB2, EGFR, PTPN22, SPI1, PLCG1, Mbp, CD5, PDGFRB, NOTCH1, FGFR1, DOK1, TUBB, SH3BP2, CBLB, CBL, FYN, SYK, LCP2, CD19, SOCS1, KHDRBS1, LMNA, TUBA1A, PHAX, ZAP70, ZNF655, DOCK2, XRCC5, PAG1, RACGAP1, MERTK, BLNK, NEK3, AOC3, ARHGDIB, DNM
Protein Size: 845
分子量 98 kDa
基因ID 7409
NCBI登录号 NM_005428, NP_005419
UniProt P15498
研究领域 Cancer, Transcription Factors
途径 TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events

使用细节

VAV1抗体详情 VAV1目标详情 贮存及处理 References for anti-VAV1 antibody (ABIN2792554) 图像 回页首
应用备注 WB Suggested Anti-VAV1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:62500
Positive Control: Human heart.
Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 845 AA

限制 仅限研究用

贮存及处理

VAV1抗体详情 VAV1目标详情 使用细节 References for anti-VAV1 antibody (ABIN2792554) 图像 回页首
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-VAV1 antibody (ABIN2792554)

VAV1抗体详情 VAV1目标详情 使用细节 贮存及处理 图像 回页首
背景

Schneider, Rudd: "CD28 and Grb-2, relative to Gads or Grap, preferentially co-operate with Vav1 in the activation of NFAT/AP-1 transcription." in: Biochemical and biophysical research communications, Vol. 369, Issue 2, pp. 616-21, 2008

图像

VAV1抗体详情 VAV1目标详情 使用细节 贮存及处理 References for anti-VAV1 antibody (ABIN2792554) 回页首
厂商提供的图像
Western Blotting (WB) image for anti-Vav 1 Oncogene (VAV1) (Middle Region) antibody (ABIN2792554) WB Suggested Anti-VAV1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...