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RCAN1 抗体

(Regulator of Calcineurin 1 (RCAN1))
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
RCAN1 抗体  (AA 60-245) RCAN1 抗体  (AA 60-245) RCAN1 抗体 (AA 60-245) (ABIN6146811)

RCAN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

RCAN1 抗体  (Middle Region) RCAN1 抗体  (Middle Region) RCAN1 抗体 (Middle Region) (ABIN2780590)

RCAN1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 绵羊, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated

RCAN1 抗体  (AA 1-100) RCAN1 抗体  (AA 1-100) RCAN1 抗体 (AA 1-100) (ABIN515079)

RCAN1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1B1 unconjugated

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RCAN1 抗体 by 适用

Find RCAN1 抗体 for a variety of species such as anti-Human RCAN1, anti-Mouse RCAN1, anti-Rat RCAN1. The species listed below are among those available. Click on a link to go to the corresponding products.

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RCAN1 抗体 by 抗原表位

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RCAN1 抗体 by 克隆形成能力

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RCAN1 抗体 by 克隆

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Popular RCAN1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (7)
Cat. No. ABIN6146811
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
  • (6)
Cat. No. ABIN2780590
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (3)
Cat. No. ABIN515079
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7242911
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN515078
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN3184361
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN515077
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (2)
Cat. No. ABIN2854669
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN1539360
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN3028975
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN3032453
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (1)
Cat. No. ABIN1387813
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7180229
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7146278
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Hamster, Horse, Human, Monkey, Pig, Rabbit, Rat, Sheep
Application WB
Validations
  • (1)
Cat. No. ABIN6749817
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our RCAN1 抗体

Wang, Rai, Hur, Smilansky, Chang, Min: "DSCR1 is required for both axonal growth cone extension and steering." in: The Journal of cell biology, Vol. 213, Issue 4, pp. 451-62, (2017) (PubMed).

Lei, Hu, Chen, Yu, Qi, Du, Gu, Lin, Yang: "RCAN1 deficiency protects against Salmonella intestinal infection by modulating JNK activation." in: Molecular immunology, Vol. 77, pp. 26-33, (2017) (PubMed).

Hong, Lee, Chung: "Ubiquitin-specific protease 22 (USP22) positively regulates RCAN1 protein levels through RCAN1 de-ubiquitination." in: Journal of cellular physiology, Vol. 230, Issue 7, pp. 1651-60, (2015) (PubMed).

Xing, Salas, Zhang, Gittler, Ludwig, Lin, Murty, Silverman, Arancio, Tycko: "Creation and characterization of BAC-transgenic mice with physiological overexpression of epitope-tagged RCAN1 (DSCR1)." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 24, Issue 1-2, pp. 30-43, (2013) (PubMed).

Junkins, MacNeil, Wu, McCormick, Lin: "Regulator of calcineurin 1 suppresses inflammation during respiratory tract infections." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 10, pp. 5178-86, (2013) (PubMed).

Stefos, Soppa, Dierssen, Becker: "NGF upregulates the plasminogen activation inhibitor-1 in neurons via the calcineurin/NFAT pathway and the Down syndrome-related proteins DYRK1A and RCAN1 attenuate this effect." in: PLoS ONE, Vol. 8, Issue 6, pp. e67470, (2013) (PubMed).

Voronov, Ochotny, Jaumouillé, Owen, Manolson, Aubin: "The R740S mutation in the V-ATPase a3 subunit increases lysosomal pH, impairs NFATc1 translocation, and decreases in vitro osteoclastogenesis." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 28, Issue 1, pp. 108-18, (2012) (PubMed).

Wang, Zhu, Chang, Min: "DSCR1 interacts with FMRP and is required for spine morphogenesis and local protein synthesis." in: The EMBO journal, Vol. 31, Issue 18, pp. 3655-66, (2012) (PubMed).

Hirakawa, Nary, Medh: "Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis." in: Journal of molecular signaling, Vol. 4, pp. 6, (2009) (PubMed).

Yang, Chen, Edgar, Li, Molkentin, Berman, Lin: "Rcan1 negatively regulates Fc epsilonRI-mediated signaling and mast cell function." in: The Journal of experimental medicine, Vol. 206, Issue 1, pp. 195-207, (2009) (PubMed).

Aliases for RCAN1 抗体

regulator of calcineurin 1 (RCAN1) 抗体
regulator of calcineurin 1 (Rcan1) 抗体
regulator of calcineurin 1b (rcan1b) 抗体
regulator of calcineurin 1 L homeolog (rcan1.L) 抗体
Down syndrome critical region gene 1 (dscr1) 抗体
regulator of calcineurin 1 (rcan1) 抗体
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RCAN1 抗体
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