anti-CXCL12 (CXCL12) 抗体产品概述

Full name:
anti-Chemokine (C-X-C Motif) Ligand 12 抗体 (CXCL12)
在www.antibodies-online.cn可供200 Chemokine (C-X-C Motif) Ligand 12 (CXCL12) 抗体的27不同的供货商。 再加上,我们可以发CXCL12 蛋白 (156)CXCL12 试剂盒 (83)和数多这个蛋白质的别的产品。 总共449 CXCL12产品已列进来了。
别名:
a-sdf1a, IRH, Pbsf, Scyb12, SDF-1, sdf1, sdf1a, Tlsf, Tpar1, xSDF-1
列出全部抗体 基因 基因ID UniProt
CXCL12 6387 P48061
CXCL12 20315 P40224
CXCL12 24772  

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抗Human CXCL12 抗体:

抗Mouse (Murine) CXCL12 抗体:

抗Rat (Rattus) CXCL12 抗体:

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引用最多的anti-CXCL12 抗体

  1. Human Monoclonal CXCL12 Primary Antibody for ELISA (Capture), FACS - ABIN4899704 : Villalba, Salvucci, Aoki, De La Luz Sierra, Gupta, Davis, Wyvill, Little, Yarchoan, Tosato: Serum inactivation contributes to the failure of stromal-derived factor-1 to block HIV-I infection in vivo. in Journal of leukocyte biology 2003 (PubMed)
    Show all 39 references for 4899704

  2. Human Polyclonal CXCL12 Primary Antibody for IF (p), IHC (p) - ABIN1386329 : Pei, Zeng, Han, Liao, Zhou, Li, Zhang, Liu, Zhang, Liu, Yao, Xu: Renal interstitial infiltration and tertiary lymphoid organ neogenesis in IgA nephropathy. in Clinical journal of the American Society of Nephrology : CJASN 2014 (PubMed)
    Show all 3 references for 1386329

  3. Human Monoclonal CXCL12 Primary Antibody for FACS - ABIN4896548 : Hoellenriegel, Zboralski, Maasch, Rosin, Wierda, Keating, Kruschinski, Burger: The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization. in Blood 2014 (PubMed)
    Show all 2 references for 4896548

  4. Cow (Bovine) Polyclonal CXCL12 Primary Antibody for WB - ABIN2774605 : Sadir, Imberty, Baleux, Lortat-Jacob: Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor-1 (SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for 2774605

  5. Human Polyclonal CXCL12 Primary Antibody for EIA, WB - ABIN116227 : Schlaepfer, Audigé, Joller, Speck: TLR7/8 triggering exerts opposing effects in acute versus latent HIV infection. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)

  6. Human Monoclonal CXCL12 Primary Antibody for FACS - ABIN4896551 : Patenaude, Perreault: Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile. in Journal of immunology (Baltimore, Md. : 1950) 2016 (PubMed)

更多抗CXCL12的相互作用对抗体

Rhesus Monkey Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. these results demonstrate that a cross-talk exists between the TGF-beta1 (显示 TGFB1 抗体) and SDF-1 pathways in choroid-retinal endothelial cells

  2. following optic nerve crush, the levels of endogenous SDF-1alpha and CXCR4 (显示 CXCR4 抗体) increase in the retina and optic nerve, where activated glial cells may act as a source of increased SDF-1alpha protein.

  3. The CXCR7 (显示 CXCR7 抗体)/CXCR4 (显示 CXCR4 抗体)/CXCL12 axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.

Medaka Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. primordial germ cell movements are shown to be the consequence of a combination of active SDF1a and SDF1b-guided migration; both SDF1 co-orthologues show only partly overlapping expression pattern and cooperate in the correct positioning of the PGCs

Human Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. Cathepsin K (显示 CTSK 抗体) cleavage of SDF-1alpha inhibits its chemotactic activity towards glioblastoma stem-like cells.

  2. High CXCL12 expression is associated with glioblastoma resistance to radiotherapy.

  3. SDF-1 promoted the proliferation of gastric cancer SGC (显示 SGCB 抗体)-7901 cells, the phosphorylation of ERK1/2 (显示 MAPK1/3 抗体), p38 (显示 CRK 抗体) and CXCR7 (显示 CXCR7 抗体) knockdown distinctly reversed these changes; the proliferation stimulated with SDF-1 was attenuated by U0126 (MEK1 (显示 MAP2K1 抗体)/2 inhibitor).

  4. Results show that SDF-1 and IL-6 expression level is regulated by CHEK2 in breast stromal fibroblasts.

  5. This study shows that expression of SDF-1alpha, eNOS (显示 NOS3 抗体) and VEGF (显示 VEGFA 抗体) were significantly higher in uterine leiomyoma than myometrium with a different expression pattern according to the size of uterine leiomyoma. However, expressions of visfatin (显示 NAMPT 抗体) and leptin (显示 LEP 抗体) had no significant differences between the two groups.

  6. Data demonstrated that sustained expression of CXCL12 by MSCs in the primary tumour site inhibits metastasis through reduction of CXCR7 (显示 CXCR7 抗体), while, in the presence of TGFbeta (显示 TGFB1 抗体), this CXCL12 effect of MSCs on tumour cells is relieved.

  7. The study demonstrated that monomeric CXCL12 was the fundamental form, which played important roles in endothelial progenitor cells' proliferation, migration, and tube-formation.

  8. the A allele and AA genotype of the SDF1- rs1111875 polymorphism produce a significant risk of MI. the GG genotype of the SDF1-rs1111875 polymorphism provides a protective effect on MI in a recessive model (GG vs. AA+AG)

  9. These results suggest that that CXCL14 (显示 CXCL14 抗体) is a positive allosteric modulator of CXCR4 (显示 CXCR4 抗体) via CXCL12 that enhances the potency of CXCR4 (显示 CXCR4 抗体) ligands.

  10. High SDF1 expression is associated with Hepatocellular Carcinoma.

Mouse (Murine) Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. Adipocytes promoted osteoclast differentiation, function and expression of adhesion-related molecules through the CXCL12/CXCR4 (显示 CXCR4 抗体) signalling pathway.

  2. these findings demonstrate that expression of Hmga2 cooperates with Jak2 (显示 JAK2 抗体)(V617F) in the pathogenesis of Mmyelofibrosis.

  3. Data demonstrated that sustained expression of CXCL12 by MSCs in the primary tumour site inhibits metastasis through reduction of CXCR7 (显示 CXCR7 抗体), while, in the presence of TGFbeta (显示 TGFB1 抗体), this CXCL12 effect of MSCs on tumour cells is relieved.

  4. CXCL12 upregulation prior to stroke onset, and its actions following stroke, contribute to the endogenous, anti-inflammatory phenotype induced by repetitive hypoxic preconditioning

  5. Results suggest that SDF-1/CXCR4 (显示 CXCR4 抗体) signaling plays an important role in the dynamics associated with adult sub-ventricular zone lineage cell proliferation and differentiation.

  6. TNF (显示 TNF 抗体) plays an inhibitory role in modulating myocardial SDF-1 production and blockade of TNF (显示 TNF 抗体) signaling by ablation of TNFR1 (显示 TNFRSF1A 抗体) and TNFR2 (显示 TNFRSF1B 抗体) genes increased SDF-1 expression in the heart. These data expand on TNF (显示 TNF 抗体) signaling-initiated mechanisms in myocardium, which may lend a more complete understanding of SDF-1 and TNFR (显示 TNFRSF1A 抗体)-derived actions in hopes of advancing ischemic heart injury treatments.

  7. CD26 (显示 DPP4 抗体)-cleavage skews CXCL12 towards beta-arrestin dependent recruitment through ACKR3 and destroys the CXCR4 (显示 CXCR4 抗体)-mediated lymphocyte chemoattractant properties of CXCL12 in vivo

  8. these data highlight AnxA1 (显示 ANXA1 抗体) as a novel determinant of neutrophil maturation and the mechanisms behind blood neutrophil homing to BM via the CXCL12/CXCR4 (显示 CXCR4 抗体) pathway.

  9. CXCL12/CXCR4 (显示 CXCR4 抗体) regulates HA and LG following corneal suture placement, and provides a novel strategy to inhibit LG. Notably, the present study is the first to demonstrate evidence that CXCL12/CXCR4 (显示 CXCR4 抗体) modulates LG in a corneal suture-induced mouse model.

  10. Female MRL/lpr (显示 FAS 抗体) mice treated with dual blockade of the chemokines CCL2 (显示 CCL2 抗体) and CXCL12 showed significantly more effective than either monotherapy in preventing proteinuria and immune complex glomerulonephritis.

Xenopus laevis Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. expression patterns of xSDF-1a, xCXCR4, and xCXCR7 during gastrulation; results suggest SDF-1 signaling supports migration of the mesendoderm cell cohort toward the animal pole and that activin/nodal signaling acts as a regulator of the expression of xSDF-1a and xCXCR4, but not xCXCR7

  2. SDF-1/CXCR4 chemokine (显示 CCL1 抗体) signaling is involved in the migration and survival or in the differentiation of PGCs in Xenopus

  3. A significant increase of stromal cell-derived factor-1alpha and CXCR4 was observed in protein extracts of idiopathic inflammatory myopathies in comparison with normal controls.

  4. SDF-1 signaling is necessary for migrations of massive numbers of cells during gastrulation.

Pig (Porcine) Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. Polymorphisms in CXCL12 are significantly associated with immunological traits in Landrace piglets and have potential application value for marker-assisted selection of pig breeding with disease resistance.

  2. The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1/CXCR4 (显示 CXCR4 抗体) axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.

Cow (Bovine) Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. There is a potential link between follicular SDF1/CXCR4 (显示 CXCR4 抗体) activation and the regulation of ovulation-related genes in cows and horses.

  2. Polymorphism of intron 2 of the SDF1 gene in Galloway, Hereford, and Russian Black Pied cattle

CXCL12 抗原简介

Antigen Summary

This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CXCL12

  • chemokine (C-X-C motif) ligand 12 (CXCL12) 抗体
  • CXCL12 (LOC100304642) 抗体
  • stromal cell-derived factor 1a (sdf1a) 抗体
  • stromal cell-derived factor 1a (a-sdf1a) 抗体
  • chemokine (C-X-C motif) ligand 12 (Cxcl12) 抗体
  • chemokine (C-X-C motif) ligand 12 (cxcl12) 抗体
  • a-sdf1a 抗体
  • IRH 抗体
  • Pbsf 抗体
  • Scyb12 抗体
  • SDF-1 抗体
  • sdf1 抗体
  • sdf1a 抗体
  • Tlsf 抗体
  • Tpar1 抗体
  • xSDF-1 抗体

Protein level used designations for CXCL12

chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) , chemokine CXCL12/SDF-1ALPHA , stromal cell-derived factor 1 , stromal cell-derived factor 1 isoform alpha , stromal cell-derived factor 1 isoform gamma , CXCL12 , stromal cell-derived factor 1a , intercrine reduced in hepatomas , pre-B cell growth-stimulating factor , 12-O-tetradecanoylphorbol 13-acetate repressed protein 1 , pre-B-cell growth-stimulating factor , thymic lymphoma cell-stimulating factor , C-X-C motif chemokine 12 , stromal-derived factor 1 , chemokine ligand 12b , stromal cell derived factor 1 , stromal cell-derived factor-1 beta , CXC chemokine , CXCL12 chemokine , SDF-1 gamma , Stromal cell-derived factor 1 , stromal cell-derived factor-1 gamma

GENE ID SPECIES
574334 Macaca mulatta
100173045 Pongo abelii
100304642 Ictalurus punctatus
100049305 Oryzias latipes
100170634 Oryzias latipes
6387 Homo sapiens
20315 Mus musculus
399030 Xenopus laevis
395180 Gallus gallus
449622 Canis lupus familiaris
494460 Sus scrofa
613811 Bos taurus
24772 Rattus norvegicus
100721137 Cavia porcellus
493806 Felis catus
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