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抗Human CXCL12 抗体:
抗Mouse (Murine) CXCL12 抗体:
抗Rat (Rattus) CXCL12 抗体:
Human Monoclonal CXCL12 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4899704
Villalba, Salvucci, Aoki, De La Luz Sierra, Gupta, Davis, Wyvill, Little, Yarchoan, Tosato: Serum inactivation contributes to the failure of stromal-derived factor-1 to block HIV-I infection in vivo. in Journal of leukocyte biology 2003
Show all 39 Pubmed References
Human Monoclonal CXCL12 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4899705
Lisignoli, Cristino, Piacentini, Cavallo, Caplan, Facchini: Hyaluronan-based polymer scaffold modulates the expression of inflammatory and degradative factors in mesenchymal stem cells: Involvement of Cd44 and Cd54. in Journal of cellular physiology 2006
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Human Polyclonal CXCL12 Primary Antibody for IF (p), IHC (p) - ABIN1386329
Pei, Zeng, Han, Liao, Zhou, Li, Zhang, Liu, Zhang, Liu, Yao, Xu: Renal interstitial infiltration and tertiary lymphoid organ neogenesis in IgA nephropathy. in Clinical journal of the American Society of Nephrology : CJASN 2014
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Human Polyclonal CXCL12 Primary Antibody for ELISA, Func - ABIN4301060
Nistala, Habibi, Aroor, Sowers, Hayden, Meuth, Knight, Hancock, Klein, DeMarco, Whaley-Connell: DPP4 inhibition attenuates filtration barrier injury and oxidant stress in the zucker obese rat. in Obesity (Silver Spring, Md.) 2014
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Human Monoclonal CXCL12 Primary Antibody for FACS - ABIN4896548
Hoellenriegel, Zboralski, Maasch, Rosin, Wierda, Keating, Kruschinski, Burger: The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization. in Blood 2014
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Human Polyclonal CXCL12 Primary Antibody for EIA, WB - ABIN116227
Schlaepfer, Audigé, Joller, Speck: TLR7/8 triggering exerts opposing effects in acute versus latent HIV infection. in Journal of immunology (Baltimore, Md. : 1950) 2006
Human Polyclonal CXCL12 Primary Antibody for Func, IHC (p) - ABIN2476433
Prociv, Walker, Whitby: Human ectopic fascioliasis in Australia: first case reports. in The Medical journal of Australia 1992
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these results demonstrate that a cross-talk exists between the TGF-beta1 (显示 TGFB1 抗体) and SDF-1 pathways in choroid-retinal endothelial cells
following optic nerve crush, the levels of endogenous SDF-1alpha and CXCR4 (显示 CXCR4 抗体) increase in the retina and optic nerve, where activated glial cells may act as a source of increased SDF-1alpha protein.
The CXCR7 (显示 CXCR7 抗体)/CXCR4 (显示 CXCR4 抗体)/CXCL12 axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.
primordial germ cell movements are shown to be the consequence of a combination of active SDF1a and SDF1b-guided migration; both SDF1 co-orthologues show only partly overlapping expression pattern and cooperate in the correct positioning of the PGCs
CCR1 activation potently induces multiple myeloma PC migration toward CCL3 (显示 CCL3 抗体) while abrogating the multiple myeloma PC migratory response to CXCL12.
High CXCL12 expression is associated with gemcitabine resistance in pancreatic cancer.
CXCL12 expression may be a useful marker for predicting the outcome in patients with esophageal squamous cell carcinoma and is a potentially new therapeutic target
our findings indicate the functional role of HBx in regulating the stem-like properties of OV6(+) CSCs in HCC (显示 FAM126A 抗体) through the MDM2 (显示 MDM2 抗体)/CXCL12/CXCR4 (显示 CXCR4 抗体)/beta-catenin (显示 CTNNB1 抗体) signaling axis, and identify HBx, MDM2 (显示 MDM2 抗体), CXCR4 (显示 CXCR4 抗体) and OV6 as a novel prognostic pathway and potential therapeutic targets for patients with HBV-related HCC (显示 FAM126A 抗体) patients
study revealed that the CXCL12-CXCR4 (显示 CXCR4 抗体) interaction is crucial for stromal cell contact-mediated early B lymphoid and pDC (显示 PNKD 抗体) differentiation from immature hematopoietic and early T lymphoid precursors with a multilineage differentiation potential but not for stromal cell contact-independent generation of early T lymphoid precursors.
SDF-1, CXCR4 (显示 CXCR4 抗体) ligand, was highly expressed in mesenchymal stem cells when co-cultured with degenerated nucleus pulposus cells. Inhibition of SDF-1 using CXCR4 (显示 CXCR4 抗体) antagonist AMD3100 abolished the MSCs-induced decrease in the mechanical moduli and increased biological activity of degenerated NPCs, suggesting a crucial role for SDF-1/CXCR4 (显示 CXCR4 抗体) signaling.
Cathepsin K (显示 CTSK 抗体) cleavage of SDF-1alpha inhibits its chemotactic activity towards glioblastoma stem-like cells.
High CXCL12 expression is associated with glioblastoma resistance to radiotherapy.
SDF-1 promoted the proliferation of gastric cancer SGC (显示 SGCB 抗体)-7901 cells, the phosphorylation of ERK1/2 (显示 MAPK1/3 抗体), p38 (显示 CRK 抗体) and CXCR7 (显示 CXCR7 抗体) knockdown distinctly reversed these changes; the proliferation stimulated with SDF-1 was attenuated by U0126 (MEK1 (显示 MAP2K1 抗体)/2 inhibitor).
Results show that SDF-1 and IL-6 expression level is regulated by CHEK2 in breast stromal fibroblasts.
The results of this study suggested that enhanced interaction between STAT3 (显示 STAT3 抗体) and p300 (显示 NOTCH1 抗体) mediated the epigenetic upregulation of CXCL12 in dorsal horn neurons, which contributed to the antitubulin chemotherapeutics-induced persistent pain
Dipeptidyl peptidase-4 (显示 DPP4 抗体) inhibition, independent of glucagon-like peptide-1 receptor (显示 GLP1R 抗体) signaling, contributes to protection of the diabetic kidney through SDF-1-dependent antioxidative and antifibrotic effects and amelioration of adverse renal hemodynamics.
High Cxcl12 expression is associated with Prostate Cancer.
Authors demonstrate that targeting the SDF-1/CXCR4 (显示 CXCR4 抗体) pathway in the context of KLF10 (显示 KLF10 抗体) deletion substantially suppresses PDAC progression
Adipocytes promoted osteoclast differentiation, function and expression of adhesion-related molecules through the CXCL12/CXCR4 (显示 CXCR4 抗体) signalling pathway.
these findings demonstrate that expression of Hmga2 cooperates with Jak2 (显示 JAK2 抗体)(V617F) in the pathogenesis of Mmyelofibrosis.
Data demonstrated that sustained expression of CXCL12 by MSCs in the primary tumour site inhibits metastasis through reduction of CXCR7 (显示 CXCR7 抗体), while, in the presence of TGFbeta (显示 TGFB1 抗体), this CXCL12 effect of MSCs on tumour cells is relieved.
CXCL12 upregulation prior to stroke onset, and its actions following stroke, contribute to the endogenous, anti-inflammatory phenotype induced by repetitive hypoxic preconditioning
Results suggest that SDF-1/CXCR4 (显示 CXCR4 抗体) signaling plays an important role in the dynamics associated with adult sub-ventricular zone lineage cell proliferation and differentiation.
TNF (显示 TNF 抗体) plays an inhibitory role in modulating myocardial SDF-1 production and blockade of TNF (显示 TNF 抗体) signaling by ablation of TNFR1 (显示 TNFRSF1A 抗体) and TNFR2 (显示 TNFRSF1B 抗体) genes increased SDF-1 expression in the heart. These data expand on TNF (显示 TNF 抗体) signaling-initiated mechanisms in myocardium, which may lend a more complete understanding of SDF-1 and TNFR (显示 TNFRSF1A 抗体)-derived actions in hopes of advancing ischemic heart injury treatments.
expression patterns of xSDF-1a, xCXCR4, and xCXCR7 during gastrulation; results suggest SDF-1 signaling supports migration of the mesendoderm cell cohort toward the animal pole and that activin/nodal signaling acts as a regulator of the expression of xSDF-1a and xCXCR4, but not xCXCR7
SDF-1/CXCR4 chemokine (显示 CCL1 抗体) signaling is involved in the migration and survival or in the differentiation of PGCs in Xenopus
A significant increase of stromal cell-derived factor-1alpha and CXCR4 was observed in protein extracts of idiopathic inflammatory myopathies in comparison with normal controls.
SDF-1 signaling is necessary for migrations of massive numbers of cells during gastrulation.
Polymorphisms in CXCL12 are significantly associated with immunological traits in Landrace piglets and have potential application value for marker-assisted selection of pig breeding with disease resistance.
The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1/CXCR4 (显示 CXCR4 抗体) axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.
There is a potential link between follicular SDF1/CXCR4 (显示 CXCR4 抗体) activation and the regulation of ovulation-related genes in cows and horses.
Polymorphism of intron 2 of the SDF1 gene in Galloway, Hereford, and Russian Black Pied cattle
This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
intercrine reduced in hepatomas
, pre-B cell growth-stimulating factor
, stromal cell-derived factor 1
, chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)
, chemokine CXCL12/SDF-1ALPHA
, stromal cell-derived factor 1 isoform alpha
, stromal cell-derived factor 1 isoform gamma
, 12-O-tetradecanoylphorbol 13-acetate repressed protein 1
, pre-B-cell growth-stimulating factor
, thymic lymphoma cell-stimulating factor
, SDF-1 gamma
, Stromal cell-derived factor 1
, stromal cell-derived factor-1 gamma
, C-X-C motif chemokine 12
, stromal-derived factor 1
, chemokine ligand 12b
, stromal cell derived factor 1
, stromal cell-derived factor-1 beta
, CXC chemokine
, CXCL12 chemokine
, chemokine ligand 12
, unm t30516