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抗Human CXCL12 抗体:
抗Mouse (Murine) CXCL12 抗体:
抗Rat (Rattus) CXCL12 抗体:
Human Monoclonal CXCL12 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4899704
Villalba, Salvucci, Aoki, De La Luz Sierra, Gupta, Davis, Wyvill, Little, Yarchoan, Tosato: Serum inactivation contributes to the failure of stromal-derived factor-1 to block HIV-I infection in vivo. in Journal of leukocyte biology 2003
Show all 39 Pubmed References
Human Monoclonal CXCL12 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4899705
Lisignoli, Cristino, Piacentini, Cavallo, Caplan, Facchini: Hyaluronan-based polymer scaffold modulates the expression of inflammatory and degradative factors in mesenchymal stem cells: Involvement of Cd44 and Cd54. in Journal of cellular physiology 2006
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Human Polyclonal CXCL12 Primary Antibody for IF (p), IHC (p) - ABIN1386329
Pei, Zeng, Han, Liao, Zhou, Li, Zhang, Liu, Zhang, Liu, Yao, Xu: Renal interstitial infiltration and tertiary lymphoid organ neogenesis in IgA nephropathy. in Clinical journal of the American Society of Nephrology : CJASN 2014
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Human Monoclonal CXCL12 Primary Antibody for FACS - ABIN4896548
Hoellenriegel, Zboralski, Maasch, Rosin, Wierda, Keating, Kruschinski, Burger: The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization. in Blood 2014
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Human Polyclonal CXCL12 Primary Antibody for ELISA, Func - ABIN4301060
Nistala, Habibi, Aroor, Sowers, Hayden, Meuth, Knight, Hancock, Klein, DeMarco, Whaley-Connell: DPP4 inhibition attenuates filtration barrier injury and oxidant stress in the zucker obese rat. in Obesity (Silver Spring, Md.) 2014
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Human Polyclonal CXCL12 Primary Antibody for EIA, WB - ABIN116228
Schlaepfer, Audigé, Joller, Speck: TLR7/8 triggering exerts opposing effects in acute versus latent HIV infection. in Journal of immunology (Baltimore, Md. : 1950) 2006
Human Monoclonal CXCL12 Primary Antibody for FACS - ABIN4896551
Patenaude, Perreault: Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile. in Journal of immunology (Baltimore, Md. : 1950) 2016
Cow (Bovine) Polyclonal CXCL12 Primary Antibody for WB - ABIN2774605
Sadir, Imberty, Baleux, Lortat-Jacob: Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor-1 (SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV. in The Journal of biological chemistry 2004
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Concomitant aberrant chemokine (显示 CCL1 抗体) CXCL12 (CXCL12) methylation and high programmed death-ligand 1 (PD-L1 (显示 CD274 抗体)) expression was significantly associated with shorter biochemical recurrence (BCR (显示 BCR 抗体))-free survival.
Results show that CXCL12 is highly expressed in metastatic lymph node (MNL) of non-small cell lung neoplasm (NSCLC) and is associated with poor prognosis which suggest that CXCL12 may play a role in tumor progression of NSCLC.
The CXCL12 rs1801157 G > A polymorphism may affect CLL development, disease progression as well as response to treatment.
KIT exon 11 codons 557-558 deletion enhanced CXCL12-mediated GIST cell migration.
the relationship between SDF-1/CXCR4 (显示 CXCR4 抗体) axis and leukemia cells is explored
Curcumin up-regulates Slit-2 (显示 SLIT2 抗体) and down-regulates the expression of CXCR4 (显示 CXCR4 抗体), SDF-1, MMP2 (显示 MMP2 抗体) and MMP9 (显示 MMP9 抗体) in Ishikawa, Hec (显示 NDC80 抗体)- 1B and primary human endometrial carcinoma cells.
CXCL12 is involved in the pathogenesis and healing of H. pylori-induced peptic ulcer.
Together, these data indicate that different mechanisms govern the flow response across GSCs, but that within a single patient, there are subpopulations of GSCs that respond to flow via either CD44 (显示 CD44 抗体)- or CXCR4 (显示 CXCR4 抗体)-CXCL12 mechanisms.
Data indicate that a constitutively monomeric CXCL12 variant reproduced the G protein-dependent and beta-arrestin-dependent responses that are associated with normal CXCR4 (显示 CXCR4 抗体) signaling and lead to cell migration.
HS had no effects on the binding of CXCL12alpha to CXCR4 (显示 CXCR4 抗体) or its biological activity, suggesting that this polysaccharide controls CXCL12 in an isoform-specific manner.
these results demonstrate that a cross-talk exists between the TGF-beta1 (显示 TGFB1 抗体) and SDF-1 pathways in choroid-retinal endothelial cells
following optic nerve crush, the levels of endogenous SDF-1alpha and CXCR4 (显示 CXCR4 抗体) increase in the retina and optic nerve, where activated glial cells may act as a source of increased SDF-1alpha protein.
The CXCR7 (显示 CXCR7 抗体)/CXCR4 (显示 CXCR4 抗体)/CXCL12 axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.
CXCL12 in cardiomyocytes is not involved in cardiac development. * CXCL12 deficiency in cardiomyocytes improves outcome of myocardial infarction. * CXCL12 overexpression in cardiomyocytes worsens outcome of myocardial infarction. * CXCL12 increases fibrosis and invasion of Th1 (显示 HAND1 抗体) cells in the heart after infarction.
CXCR4 (显示 CXCR4 抗体)(+) CD45 (显示 PTPRC 抗体)(-) bone marrow cells are niche forming for osteoclastogenesis via the SDF-1, CXCL7 (显示 PPBP 抗体), and CX3CL1 (显示 CX3CL1 抗体) signaling pathways in bone marrow.
findings suggest that PECAM-1 (显示 PECAM1 抗体) enhances SDF-1-induced chemotaxis by augmenting and prolonging activation of the PI3K/Akt (显示 AKT1 抗体)/mTORC1 pathway and Rap1 (显示 TERF2IP 抗体) and that PECAM-1 (显示 PECAM1 抗体), at least partly, exerts its activity by inhibiting SDF-1-induced internalization of CXCR4 (显示 CXCR4 抗体)
endothelial CXCR7 (显示 CXCR7 抗体)+ cells regulate CXCL12 gradient direction by controlling concentrations near but not far from the vasculature.
This study showed that release of BMP-2 (显示 BMP2 抗体) and SDF-1alpha from heparinized MCM scaffolds allows for the reduction of the applied BMP-2 (显示 BMP2 抗体) concentration since SDF-1alpha seems to enhance the osteoinductive potential of BMP-2 (显示 BMP2 抗体).
The results of this study suggested that enhanced interaction between STAT3 (显示 STAT3 抗体) and p300 (显示 NOTCH1 抗体) mediated the epigenetic upregulation of CXCL12 in dorsal horn neurons, which contributed to the antitubulin chemotherapeutics-induced persistent pain
Dipeptidyl peptidase-4 (显示 DPP4 抗体) inhibition, independent of glucagon-like peptide-1 receptor (显示 GLP1R 抗体) signaling, contributes to protection of the diabetic kidney through SDF-1-dependent antioxidative and antifibrotic effects and amelioration of adverse renal hemodynamics.
High Cxcl12 expression is associated with Prostate Cancer.
Authors demonstrate that targeting the SDF-1/CXCR4 (显示 CXCR4 抗体) pathway in the context of KLF10 (显示 KLF10 抗体) deletion substantially suppresses PDAC progression
Adipocytes promoted osteoclast differentiation, function and expression of adhesion-related molecules through the CXCL12/CXCR4 (显示 CXCR4 抗体) signalling pathway.
expression patterns of xSDF-1a, xCXCR4, and xCXCR7 during gastrulation; results suggest SDF-1 signaling supports migration of the mesendoderm cell cohort toward the animal pole and that activin/nodal signaling acts as a regulator of the expression of xSDF-1a and xCXCR4, but not xCXCR7
SDF-1/CXCR4 chemokine (显示 CCL1 抗体) signaling is involved in the migration and survival or in the differentiation of PGCs in Xenopus
A significant increase of stromal cell-derived factor-1alpha and CXCR4 was observed in protein extracts of idiopathic inflammatory myopathies in comparison with normal controls.
SDF-1 signaling is necessary for migrations of massive numbers of cells during gastrulation.
Polymorphisms in CXCL12 are significantly associated with immunological traits in Landrace piglets and have potential application value for marker-assisted selection of pig breeding with disease resistance.
The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1/CXCR4 (显示 CXCR4 抗体) axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.
There is a potential link between follicular SDF1/CXCR4 (显示 CXCR4 抗体) activation and the regulation of ovulation-related genes in cows and horses.
Polymorphism of intron 2 of the SDF1 gene in Galloway, Hereford, and Russian Black Pied cattle
Study demonstrates that forced expression of Sdf1a in the fish embryo during early development is an effective strategy to disrupt primordial germ cell migration and produce large populations of infertile fish.
miR (显示 MYLIP 抗体)-126a directs lymphatic endothelial cell sprouting and extension by interacting with Cxcl12a-mediated chemokine (显示 CCL1 抗体) signaling and Vegfc (显示 VEGFC 抗体)-Flt4 (显示 FLT4 抗体) signal axis.
filopodia distribution and their dynamics are dictated by the gradient of the chemokine (显示 CCL1 抗体) Cxcl12a.
SDF1a directly controls the migration of both leading and trailing edges of a tissue through the activation of two independent receptors, CXCR4b and CXCR7 (显示 CXCR7 抗体).
Prospective isolation and culture of sdf1(DsRed) perivascular cells demonstrated properties consistent with mesenchymal stem cells.
Study shows that the primordium generates an attractant gradient across itself by sequestering Sdf1a protein in its rear via Cxcr7 (显示 CXCR7 抗体)-mediated chemokine (显示 CCL1 抗体) uptake. This self-generated attractant gradient, combined with the route information provided by the stripe of sdf1a-expressing cells, then provides directional guidance to the migrating primordium.
gata4 (显示 GATA4 抗体) gene regulates sdf1a levels during early embryogenesis
These findings suggest an "attractive path" model in which migrating cells closely follow a dynamic SDF1a source that is refined on a transcript and protein level by miR (显示 MYLIP 抗体)-430 and Cxcr7b, respectively.
sdf-1 expression and function in the adult zebrafish have important similarities to mammals
Expression of Cxcl12 and Cxclr4 in radial glial cells of the adult zebrafish brain supports important roles for the Cxcl12/Cxcr4 (显示 CXCR4 抗体) pair in brain development and functioning.
This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
C-X-C motif chemokine 1
, GRO1 oncogene (melanoma growth stimulating activity, alpha)
, GRO1 oncogene (melanoma growth-stimulating activity)
, MGSA alpha
, fibroblast secretory protein
, growth-regulated alpha protein
, melanoma growth stimulatory activity alpha
, neutrophil-activating protein 3
, intercrine reduced in hepatomas
, pre-B cell growth-stimulating factor
, stromal cell-derived factor 1
, chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)
, chemokine CXCL12/SDF-1ALPHA
, stromal cell-derived factor 1 isoform alpha
, stromal cell-derived factor 1 isoform gamma
, 12-O-tetradecanoylphorbol 13-acetate repressed protein 1
, pre-B-cell growth-stimulating factor
, thymic lymphoma cell-stimulating factor
, SDF-1 gamma
, Stromal cell-derived factor 1
, stromal cell-derived factor-1 gamma
, growth related gene 1
, growth-regulated protein homolog alpha
, C-X-C motif chemokine 12
, stromal-derived factor 1
, chemokine ligand 12b
, stromal cell derived factor 1
, stromal cell-derived factor-1 beta
, CXC chemokine
, CXCL12 chemokine
, growth regulated protein GRO
, chemokine ligand 12
, unm t30516