anti-BCL11A (BCL11A) 抗体产品概述

Full name:
anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) 抗体 (BCL11A)
在www.antibodies-online.cn可供149 B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) 抗体的20不同的供货商。 再加上,我们可以发BCL11A 试剂盒 (8)BCL11A 蛋白 (6)和数多这个蛋白质的别的产品。 总共172 BCL11A产品已列进来了。
别名:
2810047E18Rik, BCL-11A, bcl11a, BCL11A-L, BCL11a-M, BCL11A-S, BCL11A-XL, CTIP1, D930021L15Rik, EVI9, Evi9a, Evi9b, Evi9c, HBFQTL5, mKIAA1809, wu:fi09f10, zgc:136898, ZNF856
列出全部抗体 基因 基因ID UniProt
BCL11A 14025 Q9QYE3
BCL11A 53335 Q9H165
BCL11A 305589  

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引用最多的anti-BCL11A 抗体

  1. Human Monoclonal BCL11A Primary Antibody for WB - ABIN395972 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for 395972

  2. Human Polyclonal BCL11A Primary Antibody for EIA, WB - ABIN950622 : Nuinoon, Makarasara, Mushiroda, Setianingsih, Wahidiyat, Sripichai, Kumasaka, Takahashi, Svasti, Munkongdee, Mahasirimongkol, Peerapittayamongkol, Viprakasit, Kamatani, Winichagoon, Kubo, Nakamura, Fucharoen: A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E. in Human genetics 2010 (PubMed)
    Show all 2 references for 950622

  3. Human Polyclonal BCL11A Primary Antibody for WB - ABIN653582 : Solovieff, Milton, Hartley, Sherva, Sebastiani, Dworkis, Klings, Farrer, Garrett, Ashley-Koch, Telen, Fucharoen, Ha, Li, Chui, Baldwin, Steinberg: Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster. in Blood 2010 (PubMed)
    Show all 2 references for 653582

  4. Human Polyclonal BCL11A Primary Antibody for ChIP, FACS - ABIN4300809 : Xu, Sankaran, Ni, Menne, Puram, Kim, Orkin: Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6. in Genes & development 2010 (PubMed)
    Show all 2 references for 4300809

  5. Human Polyclonal BCL11A Primary Antibody for IP, WB - ABIN153198 : Chen, Luo, Steinberg, Chui: BCL11A represses HBG transcription in K562 cells. in Blood cells, molecules & diseases 2009 (PubMed)

  6. Cow (Bovine) Polyclonal BCL11A Primary Antibody for IHC, WB - ABIN2781048 : Uda, Galanello, Sanna, Lettre, Sankaran, Chen, Usala, Busonero, Maschio, Albai, Piras, Sestu, Lai, Dei, Mulas, Crisponi, Naitza, Asunis, Deiana, Nagaraja, Perseu, Satta, Cipollina, Sollaino, Moi, Hirschhorn, Orkin, Abecasis, Schlessinger, Cao: Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

更多抗BCL11A的相互作用对抗体

Mouse (Murine) B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) interaction partners

  1. Bcl11a enhancer-deleted mice, Bcl11a(Deltaenh), phenocopy the BCL11A-null state with respect to alterations of globin expression.

  2. data identify Ctip1 as a critical control over sensory cortex development

  3. Bcl11a haploinsufficiency in mice causes impaired cognition, abnormal social behavior, and microcephaly in accordance with the human phenotype

  4. deletion of Bcl11a alters the regulation of hematopoietic stem cell quiescence, self-renewal, and fate choice

  5. This study showed that the expression of Sema3c (显示 SEMA3C 抗体) is increased in migrating Bcl11a-deficient neurons and that Bcl11a is a direct negative regulator of Sema3c (显示 SEMA3C 抗体) transcription

  6. The results of this study support a role for CTIP1 on the specification of the Subcerebral Projection Neurons in layer 5 through the repression of TBR1 and the promotion of CTIP2 (显示 BCL11B 抗体) expression.

  7. Data indicate that Myb and BCL11A cooperate with DNMT1 to achieve developmental repression of embryonic and fetal beta-like human transgenic globin genes in the adult erythroid environment.

  8. BCL11A is an essential, lineage-specific factor that regulates plasmacytoid dendritic cell development, supporting a model wherein differentiation into pDCs represents a primed "default" pathway for common dendritic cell progenitors.

  9. Bcl11a controls Flt3 (显示 FLT3 抗体) expression in early hematopoietic progenitors and is required for pDC (显示 PDC 抗体) development in vivo.

  10. Immunohistochemical staining of mouse brain showed strong expression of BCL11A in the cortical regions and also in the pyramidal cell layers in the CA1 (显示 CA1 抗体) and CA3 (显示 CA3 抗体) regions of the hippocampus.

Human B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) interaction partners

  1. Ubiquitous knockdown of BCL11A in hematopoietic stem and progenitor cells impairs hematopoietic reconstitution after transplantation.

  2. BCL11A rs11886868 and rs4671393 genotype variations and correspondingly high BCL11A plasma levels are related to laryngeal squamous cell carcinoma, besides, differences in plasma levels and genotype distribution may be related to lymph node metastasis status and the stage of laryngeal squamous cell carcinoma.

  3. BCL11A may operate in transformation of CML from chronic to acute phase in some persons

  4. The BCL11A gene was found to be potentially targeted by 12 MicroRNAs that were up-regulated in Hereditary persistence of fetal hemoglobin deletion type-2 (HPFH-2) or in Sicilian deltabeta-thalassemia. A down-regulation of BCL11A gene expression in HPFH-2 was verified by quantitative polymerase chain reaction.

  5. The BCL11A protein is highly expressed in breast cancer and knock-down of BCL11A promotes the apoptosis of MDA-MB-231 cells.

  6. his study confirms that the T/C variant (rs11886868) of the BCL11A gene causing downregulation of BCL11A gene expression in adult erythroid precursors results in the induction of HbF and ameliorates the severity of a-thalassaemia as well as sickle cell anaemia.

  7. report of an intellectual disability syndrome caused by de novo heterozygous missense, nonsense, and frameshift mutations in BCL11A, encoding a transcription factor that is a putative member of the BAF (显示 BANF1 抗体) swi (显示 SMARCA1 抗体)/snf (显示 SNRPA 抗体) chromatin-remodeling complex

  8. Reduced rate of sickle-related complications in Brazilian patients carrying HbF-promoting alleles at the BCL11A and HMIP (显示 MIPEP 抗体)-2 loci

  9. the association between modifier loci (beta-globin (显示 HBB 抗体) gene cluster, HBS1L (显示 HBS1L 抗体)-MYB (显示 MYB 抗体) intergenic region and BCL11A) and Hb F levels in Chinese Zhuang beta-TI patients

  10. The combination of the genotypes GG and CT explains more phenotypic variance than the sum of the two BCL11A SNPs taken individually.

BCL11A 抗原简介

Antigen Summary

This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.

Alternative names and synonyms associated with BCL11A

  • B cell CLL/lymphoma 11A (zinc finger protein) (Bcl11a) 抗体
  • B-cell CLL/lymphoma 11A (zinc finger protein) (BCL11A) 抗体
  • B-cell CLL/lymphoma 11A (zinc finger protein) (bcl11a) 抗体
  • B-cell CLL/lymphoma 11A (zinc finger protein) (Bcl11a) 抗体
  • B-cell CLL/lymphoma 11Aa (bcl11aa) 抗体
  • 2810047E18Rik 抗体
  • BCL-11A 抗体
  • bcl11a 抗体
  • BCL11A-L 抗体
  • BCL11a-M 抗体
  • BCL11A-S 抗体
  • BCL11A-XL 抗体
  • CTIP1 抗体
  • D930021L15Rik 抗体
  • EVI9 抗体
  • Evi9a 抗体
  • Evi9b 抗体
  • Evi9c 抗体
  • HBFQTL5 抗体
  • mKIAA1809 抗体
  • wu:fi09f10 抗体
  • zgc:136898 抗体
  • ZNF856 抗体

Protein level used designations for BCL11A

B-cell CLL/lymphoma 11A (zinc finger protein) , B-cell lymphoma/leukemia 11A , COUP-TF interacting protein 1 , COUP-TF-interacting protein 1 , EVI-9 , ecotropic viral integration site 9 protein , myeloid leukemia , B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2 , BCL-11A , BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1 , C2H2-type zinc finger protein , ecotropic viral integration site 9 homolog , ecotropic viral integration site 9 protein homolog , zinc finger protein 856 , B-cell CLL/lymphoma 11A , bcl11a.1 , fi09f10

GENE ID SPECIES
14025 Mus musculus
53335 Homo sapiens
398877 Xenopus laevis
421199 Gallus gallus
481381 Canis lupus familiaris
538680 Bos taurus
305589 Rattus norvegicus
678650 Danio rerio
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