anti-PDX1 (PDX1) 抗体产品概述

Full name:
anti-Pancreatic and Duodenal Homeobox 1 抗体 (PDX1)
在www.antibodies-online.cn可供216 Pancreatic and Duodenal Homeobox 1 (PDX1) 抗体的27不同的供货商。 再加上,我们可以发PDX1 试剂盒 (13)PDX1 蛋白 (11)和数多这个蛋白质的别的产品。 总共254 PDX1产品已列进来了。
别名:
Ad4bp, Ad4BP/SF-1, ELP, ELP-3, Ftz-F1, Ftzf1, GSF, IDX-1, Idx1, IPF-1, Ipf1, IUF1, Mody4, pdx-1, PDX1, Sf-1, SF1, STF-1, Stf1, XlHbox-8, xlhbox8, zgc:100874

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引用最多的anti-PDX1 抗体

  1. Human Monoclonal PDX1 Primary Antibody for BI, IF - ABIN967683 : Babu, Deering, Mirmira: A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis. in Molecular genetics and metabolism 2007 (PubMed)
    Show all 5 references for 967683

  2. Human Polyclonal PDX1 Primary Antibody for IF (cc), IHC (p) - ABIN729883 : Hefei, Yu, Haiqing, Xiao, Jingyuan, Dongjun: Morphological Characteristics and Identification of Islet-like Cells Derived From Rat Adipose-derived Stem Cells Cocultured with Pancreas Adult Stem Cells. in Cell biology international 2014 (PubMed)
    Show all 3 references for 729883

  3. Human Monoclonal PDX1 Primary Antibody for FACS - ABIN4897819 : Vishwakarma, Rahamathulla, Bardia, Tiwari, Srinivas, Raj, Tripura, Sandhya, Habeeb, Khan, Pande, Reddy, Reddy: In vitro quantitative and relative gene expression analysis of pancreatic transcription factors Pdx-1, Ngn-3, Isl-1, Pax-4, Pax-6 and Nkx-6.1 in trans-differentiated human hepatic progenitors. in Journal of diabetes investigation 2014 (PubMed)
    Show all 2 references for 4897819

  4. Human Polyclonal PDX1 Primary Antibody for IF, WB - ABIN392141 : Ma, Chen, Wang, Xia, Zhu, Liang, Gu, Qiao, Dai, Zou, Li, Zhang, Lan, Wong: Pancreatic duodenal homeobox-1 (PDX1) functions as a tumor suppressor in gastric cancer. in Carcinogenesis 2008 (PubMed)
    Show all 2 references for 392141

  5. Human Polyclonal PDX1 Primary Antibody for EIA, IHC (p) - ABIN360026 : Watada, Kajimoto, Kaneto, Matsuoka, Fujitani, Miyazaki, Yamasaki: Involvement of the homeodomain-containing transcription factor PDX-1 in islet amyloid polypeptide gene transcription. in Biochemical and biophysical research communications 1997 (PubMed)
    Show all 2 references for 360026

  6. Human Polyclonal PDX1 Primary Antibody for DB - ABIN390000 : Lebrun, Montminy, Van Obberghen: Regulation of the pancreatic duodenal homeobox-1 protein by DNA-dependent protein kinase. in The Journal of biological chemistry 2005 (PubMed)

  7. Human Monoclonal PDX1 Primary Antibody for IF, IHC - ABIN2452675 : Pondugala, Sasikala, Guduru, Rebala, Nageshwar Reddy: Interferon-? Decreases Nuclear Localization of Pdx-1 and Triggers ?-Cell Dysfunction in Chronic Pancreatitis. in Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2015 (PubMed)

  8. Cow (Bovine) Polyclonal PDX1 Primary Antibody for WB - ABIN2780330 : Yamada, Kato, Oguri, Yoshida, Yokoi, Watanabe, Metoki, Yoshida, Satoh, Ichihara, Aoyagi, Yasunaga, Park, Tanaka, Nozawa: Association of genetic variants with atherothrombotic cerebral infarction in Japanese individuals with metabolic syndrome. in International journal of molecular medicine 2008 (PubMed)

更多抗PDX1的相互作用对抗体

Mouse (Murine) Pancreatic and Duodenal Homeobox 1 (PDX1) interaction partners

  1. The use of a GFP reporter knocked into the endogenous Pdx1 promoter allowed us to monitor pancreatic induction based on the expression of Pdx1, a pancreatic master transcription factor, and to isolate a pure Pdx1-GFP(+) population for downstream applications.

  2. Our data suggested that lipid accumulation in the Leydig cells of the 46,XY disorders of sex development phenotype with a steroidogenic factor 1 (显示 NR5A1 抗体) mutation is due, at least in part, to the suppression of steroidogenic acute regulatory protein (显示 STAR 抗体) and CYP11A1 (显示 CYP11A1 抗体), and a resulting increase in unmetabolized cholesterol.

  3. Upon neoplastic transformation, the role of PDX1 changes from tumor-suppressive to oncogenic

  4. PDX1 role in beta-cell function and diabetes

  5. At the molecular level, administration of liraglutide induced the expression of PDX-1, MafA (显示 MAFA 抗体), p-JAK2 (显示 JAK2 抗体) and p-Stat3 (显示 STAT3 抗体) in high-fat diet-induced diabetes model to relatively normal levels.

  6. Diabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation

  7. These results suggest that Bax (显示 BAX 抗体) mediates beta-cell apoptosis in Pdx1-deficient diabetes.

  8. the role of Epidermal Growth Factor (EGF (显示 EGF 抗体)) and Poly-L-Ornithine (PLO) and PDX1 on human amnion epithelial cell differentiation process, is reported.

  9. Ets-1 (显示 ETS1 抗体) links glucotoxicity to pancreatic beta cell dysfunction through inhibiting PDX-1 expression in type 2 diabetes.

  10. Data indicate that KrasG12D;Pdx1-Cre mouse model enables one to monitor the progression of pancreatic cancer (PC) from the onset of precursor lesions to cancer development.

Human Pancreatic and Duodenal Homeobox 1 (PDX1) interaction partners

  1. Mutation in PDX1 gene is associated with Maturity Onset Diabetes of the Young.

  2. Results found that Pdx-1 overexpression exerts its effects on islet cell replication via a noncell-autonomous mechanism involving induction of a secreted soluble factor or factors. Also, Inhbb (显示 INHBB 抗体) is identified as one factor mediating the proliferative effect of Pdx-1.

  3. Our findings indicate that MET induces the differentiation of Pdx1-expressing cells within the definitive endoderm in a time-dependent manner, and suggest useful application for regenerative medicine.

  4. Pdx1 and MafA (显示 KLRG1 抗体) play crucial roles in the pancreas and maintain mature beta-cell function. Our results showed that the expression of Pdx1 and MafA (显示 KLRG1 抗体) were significantly upregulated after a sleeve gastrectomy for morbid obesity.

  5. Data show that the expression patterns of sex determining region Y-box 2 (SOX2 (显示 SOX2 抗体)) and pancreatic and duodenal homeobox 1 (Pdx1)) highly correlated with prognosis of pancreatic neuroendocrine tumors (p-NETs).

  6. The ERK (显示 EPHB2 抗体)-PDX-1 interaction in PANC-1 cells.

  7. Foxo1 (显示 FOXO1 抗体) and PDX1 are colocalized in fetal pancreatic islets, suggesting they function in parallel in beta cells.

  8. This study investigated the role of Pdx1 and its mechanism in differentiating induced pluripotent stem cells (iPSCs) into islet beta cells.

  9. the human Pdx1 is highly effective in triggering human biliary tree stem cells differentiation toward functional beta-pancreatic cells.

  10. Introduction of the PDX1 gene makes cells acquire a functional insulin (显示 INS 抗体) secretory capacity

Zebrafish Pancreatic and Duodenal Homeobox 1 (PDX1) interaction partners

  1. Diabetic pdx1-mutant zebrafish show conserved responses to nutrient overload and anti-glycemic treatment

  2. A pdx1-dependent progenitor population essential for the formation of duct-associated, second wave endocrine cells, is demonstrated.

  3. Pdx-1 plays multiple roles in maintaining the phenotype of the islet during embryogenesis.

Pig (Porcine) Pancreatic and Duodenal Homeobox 1 (PDX1) interaction partners

  1. Report pancreatic expression of Pdx-1 in pancreas.

PDX1 抗原简介

Antigen Summary

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Alternative names and synonyms associated with PDX1

  • pancreatic and duodenal homeobox 1 (pdx1) 抗体
  • pancreatic and duodenal homeobox 1 (PDX1) 抗体
  • nuclear receptor subfamily 5, group A, member 1 (Nr5a1) 抗体
  • pancreatic and duodenal homeobox 1 (Pdx1) 抗体
  • Ad4bp 抗体
  • Ad4BP/SF-1 抗体
  • ELP 抗体
  • ELP-3 抗体
  • Ftz-F1 抗体
  • Ftzf1 抗体
  • GSF 抗体
  • IDX-1 抗体
  • Idx1 抗体
  • IPF-1 抗体
  • Ipf1 抗体
  • IUF1 抗体
  • Mody4 抗体
  • pdx-1 抗体
  • PDX1 抗体
  • Sf-1 抗体
  • SF1 抗体
  • STF-1 抗体
  • Stf1 抗体
  • XlHbox-8 抗体
  • xlhbox8 抗体
  • zgc:100874 抗体

Protein level used designations for PDX1

pancreatic and duodenal homeobox 1 , pancreas/duodenum homeobox protein 1 , STF-1 , adrenal 4-binding protein , embryonal LTR-binding protein , embryonal long terminal repeat-binding protein , fushi tarazu 1 factor homolog , fushi tarazu factor homolog 1 , steroid hormone receptor Ad4BP , steroid hydroxylase positive regulator , steroidogenic factor 1 , IPF-1 , IUF-1 , glucose-sensitive factor , insulin promoter factor 1, homeodomain transcription factor , insulin upstream factor 1 , islet/duodenum homeobox-1 , pancreatic-duodenal homeobox factor 1 , somatostatin transcription factor 1 , somatostatin-transactivating factor 1 , pancreatic and duodenum homeobox 1 , pancreatic duodenal homeobox gene 1 , islet/duodenum homeobox 1 , pancreatic and duodenal homeobox gene 1 , IDX-1 , Insulin promoter factor 1 , insulin promotor factor 1 , somatostatin transactivating factor 1 , homeodomain protein PDX1 , homeodomain protein PDX-1 , Homeobox protein 8 , XlHbox 8 protein

GENE ID SPECIES
100101706 Xenopus (Silurana) tropicalis
100240682 Felis catus
100286705 Salmo salar
26423 Mus musculus
83826 Rattus norvegicus
3651 Homo sapiens
493994 Canis lupus familiaris
18609 Mus musculus
29535 Rattus norvegicus
30721 Danio rerio
452507 Pan troglodytes
771348 Gallus gallus
397288 Sus scrofa
538927 Bos taurus
100337610 Xenopus laevis
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