anti-TRAF2 (TRAF2) 抗体产品概述

Full name:
anti-TNF Receptor-Associated Factor 2 抗体 (TRAF2)
在www.antibodies-online.cn可供200 TNF Receptor-Associated Factor 2 (TRAF2) 抗体的27不同的供货商。 再加上,我们可以发TRAF2 蛋白 (9)和数多这个蛋白质的别的产品。 总共234 TRAF2产品已列进来了。
别名:
AI325259, MGC:45012, TANK, TRAP, TRAP3
列出全部抗体 基因 基因ID UniProt
TRAF2 7186 Q12933
TRAF2 22030 P39429
TRAF2 311786  

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引用最多的anti-TRAF2 抗体

  1. Human Monoclonal TRAF2 Primary Antibody for WB - ABIN967631 : Arch, Gedrich, Thompson: Translocation of TRAF proteins regulates apoptotic threshold of cells. in Biochemical and biophysical research communications 2000 (PubMed)
    Show all 7 references for 967631

  2. Human Monoclonal TRAF2 Primary Antibody for IHC (p), IHC - ABIN252657 : van Galen, Muris, Giroth, Vos, Ossenkoppele, Meijer, Oudejans: Expression of TNF-receptor associated factor 2 correlates with poor progression-free survival time in ABC-like primary nodal diffuse large B-cell lymphomas. in Histopathology 2008 (PubMed)
    Show all 3 references for 252657

  3. Human Polyclonal TRAF2 Primary Antibody for ICC, FACS - ABIN252172 : Döppler, Liou, Storz: Downregulation of TRAF2 mediates NIK-induced pancreatic cancer cell proliferation and tumorigenicity. in PLoS ONE 2013 (PubMed)
    Show all 3 references for 252172

  4. Human Monoclonal TRAF2 Primary Antibody for IF, WB - ABIN659110 : Alvarez, Harikumar, Hait, Allegood, Strub, Kim, Maceyka, Jiang, Luo, Kordula, Milstien, Spiegel: Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. in Nature 2010 (PubMed)

  5. Human Polyclonal TRAF2 Primary Antibody for IF (p), IHC (p) - ABIN673479 : Lei, Bai, Yang, Lai, Qiu, Yang, Lian: Gsdma3 is a new factor needed for TNF-?-mediated apoptosis signal pathway in mouse skin keratinocytes. in Histochemistry and cell biology 2012 (PubMed)

  6. Human Polyclonal TRAF2 Primary Antibody for IHC, ELISA - ABIN190911 : Xu, Huang, Liu, Han: Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation. in The Journal of biological chemistry 2006 (PubMed)

更多抗TRAF2的相互作用对抗体

Human TNF Receptor-Associated Factor 2 (TRAF2) interaction partners

  1. TRAF2 and OTUD7B (显示 OTUD7B 抗体) govern a ubiquitin-dependent switch that regulates mTORC2 (显示 CRTC2 抗体) signalling

  2. destabilization of TRAF2 by miR-17 reduced the ability of TRAF2 to associate with cIAP2 (显示 BIRC3 抗体), resulting in the downregulation of TNF-alpha (显示 TNF 抗体)-induced NF-kappaBp65, c-Jun (显示 JUN 抗体), and STAT3 (显示 STAT3 抗体) nuclear translocation and the production of IL-6 (显示 IL6 抗体), IL-8 (显示 IL8 抗体), MMP-1 (显示 MMP1 抗体), and MMP-13 (显示 MMP13 抗体) in human rheumatoid arthritis synovial fibroblasts.

  3. HOXA1 (显示 HOXA1 抗体)-mediated activation of NF-kappaB (显示 NFKB1 抗体) is non-transcriptional and the RBCK1 (显示 RBCK1 抗体) and TRAF2 influences on NF-kappaB (显示 NFKB1 抗体) are epistatic to HOXA1 (显示 HOXA1 抗体)

  4. RIPK1 (显示 RIPK1 抗体) collaborates with TRAF2 to inhibit murine and human hepatocarcinogenesis.

  5. Data suggest that TRAF2 (TNF receptor-associated factor 2) negatively regulates (1) TNFR1- (tumor necrosis factor binding protein 1 (显示 TNFRSF1A 抗体))-induced apoptosis, (2) TNFR2 (显示 TNFRSF1B 抗体)- (tumor necrosis factor (显示 TNF 抗体) receptor type 2)-induced non-canonical NFkappaB (显示 NFKB1 抗体) signaling, and (3) TNF- (tumor necrosis factor (显示 TNF 抗体))-induced necroptosis. [REVIEW]

  6. Study presents the characterization of the peptide binding preferences of TRAFs 2, 3, and 5 using deep mutational scanning. The three TRAF (显示 TRAF1 抗体) proteins demonstrated different preferences for binding to members of the CD40 (显示 CD40 抗体) library, and three peptides from that library individually showed striking differences in affinity for the three TRAFs.

  7. The data demonstrate a novel and unexpected function of BIG1 (显示 CNTN3 抗体) that regulates TNFR1 (显示 TNFRSF1A 抗体) signaling by targeting TRAF2.

  8. TRAF2 expression was increased in gastric cancer patients as a result of DNA hypomethylation.

  9. Data show that when death receptor 5 (DR5 (显示 TNFRSF10B 抗体)) is suppressed, caspase-8 (显示 CASP8 抗体) may recruit and stabilize TNF receptor-associated factor 2 (TRAF2) to form a metastasis and invasion signaling complex, resulting in activation of ERK (显示 EPHB2 抗体) signaling.

  10. these findings reveal a novel mechanism by which TRAF2 mediates Lys63-linked ubiquitination of DUSP14 (显示 DUSP14 抗体), leading to DUSP14 (显示 DUSP14 抗体) activation in T cells

Mouse (Murine) TNF Receptor-Associated Factor 2 (TRAF2) interaction partners

  1. work reveals that simulated microgravity promotes the apoptotic response through a combined modulation of the Uev1A/TICAM/TRAF (显示 TRAF1 抗体)/NF-kappaB (显示 NFKB1 抗体)-regulated apoptosis and the p53 (显示 TP53 抗体)/PCNA (显示 PCNA 抗体)- and ATM (显示 ATM 抗体)/ATR (显示 ATR 抗体)-Chk1 (显示 CHEK1 抗体)/2-controlled DNA-damage response pathways.

  2. Traf2 mediates the pro-survival pathway in the heart by suppressing necroptotic signaling.

  3. Targeting TRAF2 may be useful as a therapeutic approach for immunosuppression-free islet allograft survival that avoids the thromboembolic complications associated with the use of anti-CD40L (显示 CD40LG 抗体) antibodies.

  4. Celastrol promotes Nur77 (显示 NR4A1 抗体) migration from the nucleus to mitochondria, where it is ubiquitinated by TRAF2. Ubiquitinated Nur77 (显示 NR4A1 抗体) then interacts with p62/SQSTM1 (显示 SQSTM1 抗体), leading to autophagy of dysfunctional mitochondria and alleviation of inflammation.

  5. TRAF2 and OTUD7B (显示 OTUD7B 抗体) govern a ubiquitin-dependent switch that regulates mTORC2 (显示 CRTC2 抗体) signalling

  6. this study shows that TRAF2 and TRAF5 (显示 TRAF5 抗体) work as important regulators of the IL-6R signaling needed for Th17 development

  7. Keratinocyte-specific deletion of Traf2, but not Sphk1 (显示 SPHK1 抗体) deficiency, disrupted TNF (显示 TNF 抗体) mediated NF-kappaB (显示 NFKB1 抗体) and MAP kinase (显示 MAPK1 抗体) signalling and caused epidermal hyperplasia and psoriatic skin inflammation.

  8. TRAF2 functions as a key activator of MST1 (显示 MST1 抗体) in oxidative stress-induced (显示 SQSTM1 抗体) intracellular signaling processes.

  9. Proinflammatory TLR signalling is regulated by a TRAF2-dependent proteolysis mechanism in macrophages.

  10. NFkappaB anti-apoptotic target genes TNF receptor-associated factor 1 (TRAF1 (显示 TRAF1 抗体)), TNF receptor-associated factor 2 (TRAF2), cellular inhibitor of apoptosis (cIAP2 (显示 BIRC3 抗体)), and Ferritin heavy chain (FTH1 (显示 FTH1 抗体)) were increased following Losartan treatment

TRAF2 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined.

Alternative names and synonyms associated with TRAF2

  • TNF-receptor-associated factor 2 (Traf2) 抗体
  • conjugal transfer protein TraF (traF2) 抗体
  • TNF receptor-associated factor 2 (TRAF2) 抗体
  • TNF receptor-associated factor 2 (Traf2) 抗体
  • Tnf receptor-associated factor 2 (Traf2) 抗体
  • AI325259 抗体
  • MGC:45012 抗体
  • TANK 抗体
  • TRAP 抗体
  • TRAP3 抗体

Protein level used designations for TRAF2

GLEAN_07706 , conjugal transfer protein TraF , E3 ubiquitin-protein ligase TRAF2 , tumor necrosis factor type 2 receptor associated protein 3 , tumor necrosis factor type 2 receptor-associated protein 3 , TRAF family member-associated NFKB activator , TNF receptor-associated factor 2

GENE ID SPECIES
661716 Tribolium castaneum
5816473 Bordetella petrii DSM 12804
10845633 Oligotropha carboxidovorans OM5
7186 Homo sapiens
480673 Canis lupus familiaris
512355 Bos taurus
22030 Mus musculus
311786 Rattus norvegicus
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