anti-人 BDNF 抗体 for Immunohistochemistry

Recommended BDNF Antibody (supplied by: Log in to see )

抗原
Brain-Derived Neurotrophic Factor (BDNF) 抗体
  • bdnf-A
  • BDNF
  • Bdnf
  • bdnf
  • ANON2
  • BULN2
  • brain-derived neurotrophic factor
  • brain derived neurotrophic factor
  • brain-derived neurotrophic factor-like
  • bdnf
  • bdnf-A
  • BDNF
  • Bdnf
  • bdnf-b
  • LOC100356949
抗原表位
Middle Region
30
23
18
8
7
6
6
6
6
5
5
5
5
5
4
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
适用
犬, 马, 人, 小鼠, 猪, 兔, 大鼠
305
128
110
15
14
10
9
7
6
5
5
4
3
2
2
1
宿主

223
104
11
10
9
5
克隆类型
多克隆
标记
This BDNF antibody is un-conjugated
30
20
13
6
6
5
5
5
4
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
283
150
108
70
67
55
42
23
13
11
9
4
4
2
2
2
1
1
1
1
选项
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产品编号 ABIN2777093
$ 289.00
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.900387 ABIN4899237 CyTOF FACS IHC Chicken IgY AA 129-247 Log in to see Polyclonal 5
8.900387 ABIN1981374 IHC WB Rabbit IgG AA 206-236, C-Term Log in to see Polyclonal
8.900387 ABIN4283815 IHC IHC (p) WB Rabbit Log in to see Polyclonal
8.900387 ABIN3030196 FACS IF IHC ELISA WB Rabbit Ig Fraction AA 206-236 Log in to see Polyclonal
8.900387 ABIN285669 IHC ELISA WB Chicken IgY Log in to see Polyclonal
8.900387 ABIN4892211 IHC WB Rabbit Log in to see Polyclonal
8.900387 ABIN2404176 IHC WB Rabbit IgG Log in to see Polyclonal
8.900387 ABIN2425611 IHC ELISA Rabbit IgG Log in to see Polyclonal
1 ABIN409162 ICC IF IHC IHC (fro) WB Rabbit Log in to see Polyclonal 2
1 ABIN4283827 FACS ICC IF IHC IHC (p) WB Mouse IgG2a kappa Log in to see 14C8-1D9 1
1 ABIN1871274 IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN5539690 ELISA IF IHC Goat Internal Region Log in to see Polyclonal
1 ABIN350451 IHC WB Rabbit N-Term Log in to see Polyclonal 7
1 ABIN409229 ICC IHC (fro) IF IHC WB Rabbit Log in to see Polyclonal
1 ABIN465693 IHC Neut ELISA WB Rabbit Log in to see Polyclonal
1 ABIN5609809 ELISA IF IHC Goat Internal Region Log in to see Polyclonal
1 ABIN1584074 IHC ELISA WB Rabbit Middle Region Log in to see Polyclonal
1 ABIN4283816 IHC IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN1171949 IHC ELISA WB Biotin Rabbit IgG AA 129-247 Log in to see Polyclonal
1 ABIN350454 IHC WB Rabbit IgG N-Term Log in to see Polyclonal 7

General

抗原 Brain-Derived Neurotrophic Factor (BDNF) 抗体
抗原表位 Middle Region
(30), (23), (18), (8), (7), (6), (6), (6), (6), (5), (5), (5), (5), (5), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用 犬, 马, 人, 小鼠, 猪, 兔, 大鼠
(305), (128), (110), (15), (14), (10), (9), (7), (6), (5), (5), (4), (3), (2), (2), (1)
宿主
(223), (104), (11), (10), (9), (5)
克隆类型
多克隆
标记 This BDNF antibody is un-conjugated
(30), (20), (13), (6), (6), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Immunohistochemistry (IHC), Western Blotting (WB)
(283), (150), (108), (70), (67), (55), (42), (23), (13), (11), (9), (4), (4), (2), (2), (2), (1), (1), (1), (1)
Pubmed 7个引用可参考
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BDNF抗体详情

BDNF目标详情 使用细节 贮存及处理 References for anti-BDNF antibody (ABIN2777093) 图像
Blocking Peptide Blocking peptide for this product available: ABIN973798
序列 EWVTAADKKT AVDMSGGTVT VLEKVPVSKG QLKQYFYETK CNPMGYTKEG
预测反应 Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
产品特性 This is a rabbit polyclonal antibody against BDNF. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
免疫原 The immunogen is a synthetic peptide directed towards the middle region of human BDNF

BDNF目标详情

BDNF抗体详情 使用细节 贮存及处理 References for anti-BDNF antibody (ABIN2777093) 图像 回页首
抗原
别名 BDNF (BDNF Antibody 摘要)
背景 BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression BDNF is reduced in both Alzheimer's and Huntington disease patients. BDNF may play a role in the regulation of stress response and in the biology of mood disorders.The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene, but the full-length nature of only some could be determined.
Alias Symbols: MGC34632
Protein Interaction Partner: UBC, AGO3, INPP5K, F11R, JUNB, APP, ELAVL1, Ntrk2, CADPS2, MBTPS1, SORT1, NOS3, NTF4, NTF3, ESR1, NCAM1, CPE, BDNF,
Protein Size: 247
分子量 27 kDa
基因ID 627
NCBI登录号 NM_001709, NP_001700
UniProt P23560
研究领域 Cardiovascular, Atherosclerosis, Alzheimer's Disease, Hormones
途径 RTK signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity

使用细节

BDNF抗体详情 BDNF目标详情 贮存及处理 References for anti-BDNF antibody (ABIN2777093) 图像 回页首
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 247 AA

限制 仅限研究用

贮存及处理

BDNF抗体详情 BDNF目标详情 使用细节 References for anti-BDNF antibody (ABIN2777093) 图像 回页首
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-BDNF antibody (ABIN2777093)

BDNF抗体详情 BDNF目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

McCarthy, Mueller, Cannon, Huizenga, Darnell, Bhide, Sadri-Vakili: "Prenatal Cocaine Exposure Alters BDNF-TrkB Signaling in the Embryonic and Adult Brain." in: Developmental neuroscience, Vol. 38, Issue 5, pp. 365-374, 2017

McCarthy, Bell, Cannon, Mueller, Huizenga, Sadri-Vakili, Fadool, Bhide: "Reversal Learning Deficits Associated with Increased Frontal Cortical Brain-Derived Neurotrophic Factor Tyrosine Kinase B Signaling in a Prenatal Cocaine Exposure Mouse Model." in: Developmental neuroscience, Vol. 38, Issue 5, pp. 354-364, 2016

Kight, McCarthy: "Sex differences and estrogen regulation of BDNF gene expression, but not propeptide content, in the developing hippocampus." in: Journal of neuroscience research, Vol. 95, Issue 1-2, pp. 345-354, 2016

Kasemeier-Kulesa, Morrison, Lefcort, Kulesa: "TrkB/BDNF signalling patterns the sympathetic nervous system." in: Nature communications, Vol. 6, pp. 8281, 2015

Vassoler, White, Schmidt, Sadri-Vakili, Pierce: "Epigenetic inheritance of a cocaine-resistance phenotype." in: Nature neuroscience, Vol. 16, Issue 1, pp. 42-7, 2012

McCarthy, Zhang, Darnell, Sangrey, Yanagawa, Sadri-Vakili, Bhide: "Cocaine alters BDNF expression and neuronal migration in the embryonic mouse forebrain." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 38, pp. 13400-11, 2011

背景

Hashimoto, Moriguchi, Yamashita, Mori, Nemoto, Okada, Hori, Noguchi, Kunugi, Ohnishi: "Dose-dependent effect of the Val66Met polymorphism of the brain-derived neurotrophic factor gene on memory-related hippocampal activity." in: Neuroscience research, Vol. 61, Issue 4, pp. 360-7, 2008

图像

BDNF抗体详情 BDNF目标详情 使用细节 贮存及处理 References for anti-BDNF antibody (ABIN2777093) 回页首
厂商提供的图像
Western Blotting (WB) image for anti-Brain-Derived Neurotrophic Factor (BDNF) (Middle Region) antibody (ABIN2777093) anti-Brain-Derived Neurotrophic Factor (BDNF) (Middle Region) antibody
Immunohistochemistry (IHC) image for anti-Brain-Derived Neurotrophic Factor (BDNF) (Middle Region) antibody (ABIN2777093) anti-Brain-Derived Neurotrophic Factor (BDNF) (Middle Region) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-Brain-Derived Neurotrophic Factor (BDNF) (Middle Region) antibody (ABIN2777093) anti-Brain-Derived Neurotrophic Factor (BDNF) (Middle Region) antibody (Image 3)