anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) 抗体产品概述

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anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 抗体 (CYP19A1)
在www.antibodies-online.cn可供158 Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) 抗体的23不同的供货商。 再加上,我们可以发Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 试剂盒 (55)Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 蛋白 (8)和数多这个蛋白质的别的产品。 总共229 Cytochrome P450, Family 19, Subfamily A, Polypeptide 1产品已列进来了。
别名:
Ar, ArKO, aro, ARO1, Aromatase, CPV1, CYAR, cyp19, cyp19a, CYP19A1, CYP19P1, CYPXIX, Int-5, Int5, P-450AROM, P450 arom, P450AROM, p450arom-A
列出全部抗体 基因 基因ID UniProt
CYP19A1 1588 P11511
CYP19A1 25147  
CYP19A1 13075 P28649

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引用最多的anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 抗体

  1. Baboon Monoclonal CYP19A1 Primary Antibody for IF, IHC (p) - ABIN120192 : Colette, Lousse, Defrère, Curaba, Heilier, Van Langendonckt, Mestdagt, Foidart, Loumaye, Donnez: Absence of aromatase protein and mRNA expression in endometriosis. in Human reproduction (Oxford, England) 2009 (PubMed)
    Show all 16 references for 120192

  2. Baboon Monoclonal CYP19A1 Primary Antibody for IF, IHC (p) - ABIN488154 : Bender, Zhou, Wilkars, Fester, Lanowski, Paysen, König, Rune: Roles of 17ß-estradiol involve regulation of reelin expression and synaptogenesis in the dentate gyrus. in Cerebral cortex (New York, N.Y. : 1991) 2010 (PubMed)
    Show all 15 references for 488154

  3. Human Polyclonal CYP19A1 Primary Antibody for ICC, IF - ABIN151143 : Beyer, Green, Barker, Huskisson, Hutchison: Aromatase-immunoreactivity is localised specifically in neurones in the developing mouse hypothalamus and cortex. in Brain research 1994 (PubMed)
    Show all 6 references for 151143

  4. Chicken Polyclonal CYP19A1 Primary Antibody for IHC, WB - ABIN223293 : Bukulmez, Hardy, Carr, Word, Mendelson: Inflammatory status influences aromatase and steroid receptor expression in endometriosis. in Endocrinology 2008 (PubMed)
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  5. Human Polyclonal CYP19A1 Primary Antibody for FACS, IF (p) - ABIN674529 : Lan, Chen, Jan, Chen, Ho: Differentiation of human embryonic stem cells into functional ovarian granulosa-like cells. in The Journal of clinical endocrinology and metabolism 2013 (PubMed)
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  6. Human Polyclonal CYP19A1 Primary Antibody for EIA, WB - ABIN359546 : Ikeda, Sasazuki, Natsukawa, Shaura, Koizumi, Kasuga, Ohnami, Sakamoto, Yoshida, Iwasaki, Tsugane: Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population. in The American journal of gastroenterology 2008 (PubMed)
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  7. Human Polyclonal CYP19A1 Primary Antibody for EIA, IHC (p) - ABIN359737 : Xita, Georgiou, Lazaros, Psofaki, Kolios, Tsatsoulis: The synergistic effect of sex hormone-binding globulin and aromatase genes on polycystic ovary syndrome phenotype. in European journal of endocrinology / European Federation of Endocrine Societies 2008 (PubMed)
    Show all 2 references for 359737

  8. Human Polyclonal CYP19A1 Primary Antibody for ELISA, WB - ABIN238672 : Van Poznak, Hayes: Aromatase inhibitors for the treatment of breast cancer: is tamoxifen of historical interest only? in Journal of the National Cancer Institute 2006 (PubMed)

更多抗Cytochrome P450, Family 19, Subfamily A, Polypeptide 1的相互作用对抗体

Pig (Porcine) Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) interaction partners

  1. CYP19A1 is involved in sperm fertility and its expression in sperm plays an important role in fertilization.

  2. P450arom was expressed in all layers of the arterial and venous vessels of the spermatic cord with higher intensity of staining in June long daylight) compared to December(short daylight).

  3. Decreased estradiol production via suppression of aromatase may be one of the mechanisms by which miR (显示 MYLIP 抗体)-378 regulates the maturation of cumulus-oocyte complexes.

  4. show that micro-RNA378 (miR (显示 MYLIP 抗体)-378) is spatiotemporally expressed in porcine granulosa cells, the cells that generate estradiol in the ovary during follicular development, in an inverse manner compared with the expression of aromatase

  5. Pig ejaculated spermatozoa express aromatase.

  6. The presence of aromatase and 11beta-HSD 2 (显示 HSD11B2 抗体) in Leydig cells increased, together with germ and Sertoli cell numbers.

  7. This study demonstrates that transferrin (显示 Tf 抗体) had a dose-dependent inhibitory effect on follicle stimulating hormone-stimulated aromatase activity.

Human Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) interaction partners

  1. Leptin (显示 LEP 抗体) increased aromatase expression in breast cancer cells, which was correlated with COX-2 (显示 COX2 抗体) upregulation.

  2. Immunohistochemical analysis of 221 invasive breast cancer cases indicated that 87.3% (193/221) had at least 5% aromatase positive cells.

  3. CYP19A1 amplification caused increased aromatase activity.

  4. The reduction of DHT obese homozygotic twins could be linked to its increased degradation by AKR1C2 (显示 AKR1C2 抗体) and HSD11B1 (显示 HSD11B1 抗体), and increased estrogen levels could be linked to increased adiposity-related expression of aromatase in adipose tissue.

  5. The authors proposed that NF2 (显示 NF2 抗体) behaves as a protein sensing tissue damage and aromatase-driven local estrogen formation, eventually leading to regulation of stem cells differentiation and tissue repair by liver cancer cells. (Review)

  6. The CYP19A1 rs10046 variant T/T favors lower incidence of hot flashes/sweating under exemestane + OFS treatment, suggesting endocrine-mediated effects.

  7. R264 polymorphism causes an intrinsic alteration of aromatase activity together with a different consensus for phosphorylation by different kinases, indicating that estrogen production can be different when such mutations are present

  8. analysis of how sildenafil inhibits aromatase in human cells by molecular docking simulation

  9. 16(beta)-OH-androstenedione generated by CYP21A2 (显示 CYP21A2 抗体) serves as a substrate for CYP19A1

  10. Description of a novel functional FSHR (显示 FSHR 抗体) expression, where FSH (显示 BRD2 抗体)-stimulated CYP19A1 expression and estrogen production in recto-vaginal endometriotic nodules (RVEN) are demonstrated. This locally FSH (显示 BRD2 抗体)-induced estrogen production may contribute to the pathology, development, progression, and severity of RVEN .

Cow (Bovine) Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) interaction partners

  1. in granulosa cells of dominant follicles the concentration of CYP19P1 mRNA was very low compared to CYP19A1 mRNA. CONCLUSIONS: CYP19P1 and CYP19A1 transcripts might interfere in placental cotyledons

  2. These data suggest that a major reason why CYP19A1 is not expressed in luteinized cells (and the corpus luteum) of ruminants may be the stimulatory effect of FOXL2 (显示 FOXL2 抗体), which does not appear to be the case in the human and rat.

  3. This study evaluated the relationships among aromatase, IGF-1 (显示 IGF1 抗体), IGF2R (显示 IGF2R 抗体), and FSH (显示 BRD2 抗体) levels expressed in ovarian follicles of cattle selected for twin pregnancies.

  4. Data indicated de novo DNA methylation (显示 HELLS 抗体) fter the luteinizing hormone-induced down-regulation of CYP19A1 expression, suggesting that DNA methylation (显示 HELLS 抗体) might play a role for permanent silencing of previously down-regulated genes.

  5. P450(AROM) is localized in the cytoplasm and only seldom present in the fine extensions of the cells in frontal cortex.

  6. Granulosa and theca of well-characterized large bovine follicles were isolated before and after the LH surge. CYP19A1, HSD3B1 (显示 HSD3B1 抗体), and CYP17A1 (显示 CYP17A1 抗体) transcripts were quantified by real-time PCR (qPCR) and the chromatin condensation was determined.

  7. DNA methylation (显示 HELLS 抗体) may have a role in the permanent shutdown of promoter 2-directed cytochrome P450 19A1(CYP19A1) expression in large (granulosa derived) lutein cells

  8. fetal ovary of cattle has the steroidogenic enzyme aromatase to convert androgens to estradiol-17beta, and estrogen receptors alpha and beta to facilitate an estrogen response within the fetal ovary

  9. granulosa cell clustering is accompanied by marked increases in FSHr (显示 FSHR 抗体), IGF-1r (显示 IGF1R 抗体), and p450 arom expression, and precedes induction and subsequent peak E2 production

  10. demonstrates that cattle and sheep use different promoters to direct aromatase(Cyp19) expression during pregnancy

Mouse (Murine) Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) interaction partners

  1. Aromatase-knockout (ArKO) mice cannot synthesize estrogens in vivo. Male ArKO mice developed hepatic steatosis accompanied by high testosterone levels.

  2. results show that the Aha1 (显示 AHSA1 抗体)-Hsp90 (显示 HSP90 抗体)-PKM2/HIF-1alpha (显示 HIF1A 抗体) axis mediates the induction of aromatase in Li-Fraumeni Syndrome (显示 TP53 抗体).

  3. aromatase could modulate pituitary LH-positive cells in males through local estradiol synthesis.

  4. Findings indicate that sex chromosome factors determine sex differences in aromatase expression in the stria terminalis and in the anterior amygdaloid area of mouse embryos.

  5. CELF1 (显示 CELF1 抗体) downregulates Cyp19a1 (Aromatase) posttranscriptionally to achieve high concentrations of testosterone compatible with spermiogenesis completion.

  6. Aromatase plays an important role in the survival of metastatic ERalpha (显示 ESR1 抗体) breast cancer cells by suppressing anoikis.

  7. aromatase may play a key role in the pathogenesis of Sjogren syndrome-like lesions by controlling the target organ and adipose tissue-associated macrophage; increased MPC1 (显示 BRP44L 抗体) protein expression has a role in adiposity

  8. The protective effect of female gender on abdominal aortic aneurysms is due to estrogen synthesis and requires the presence of both ovarian and extragonadal/peripheral aromatase.

  9. Aromatase signaling is common in the mouse brain; locally synthesized brain estrogens could mediate biological effects by activating pre- and post-synaptic estrogen alpha and beta receptors, and androgen receptors.

  10. Male Aromatase knockout mice develop hepatic glucose intolerance.

Horse (Equine) Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) interaction partners

  1. co-localization of estrogen receotirs with aromatase in horse trophoblast suggests auto- or intracrine functions of oestrogens in this cell type

Goat Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) interaction partners

  1. These data suggest that a major reason why CYP19A1 is not expressed in luteinized cells (and the corpus luteum) of ruminants may be the stimulatory effect of FOXL2 (显示 FOXL2 抗体), which does not appear to be the case in the human and rat.

  2. Relative mRNA expression for insulin (显示 INS 抗体) and FSH (显示 BRD2 抗体) receptors and cytochrome P450 aromatase in cultured follicles.

Xenopus laevis Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) interaction partners

  1. We found that cyp19a1 expression is highly regionalized in the brains of both sexes.

  2. Cyp19a1 expression leads to female sex determination in Xenopus laevis.

  3. brain-specific (显示 CALY 抗体) promoter/exon I.f of the cyp19a1 has cis (显示 CISH 抗体)-elements for several transcriptional factors

  4. binding sequences to a specific trans-activating factor upstream of the p450 (显示 POR 抗体) aromatase promoter II

  5. The ontogenetic patterns of Aro, Srd5a1 (显示 SRD5A1 抗体) and Srd5a2 (显示 SRD5A2 抗体) suggest that these genes are involved in sexual differentiation of gonads and brain already in early developmental stages.

Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) 抗原简介

Antigen Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity\; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.

Alternative names and synonyms associated with Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1)

  • aromatase (SAV_2383) 抗体
  • cytochrome P450 aromatase (pfcyp19b-tstr) 抗体
  • cytochrome P450 19A1 (CYP19A1) 抗体
  • cytochrome P450 19A3 (CYP19A3) 抗体
  • cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP19A1) 抗体
  • cytochrome P450, family 19 (CYP19) 抗体
  • cytochrome P450, family 19, subfamily A, polypeptide 1 (CYP19A1) 抗体
  • cytochrome P450, family 19, subfamily a, polypeptide 1 (Cyp19a1) 抗体
  • cytochrome P450, family 19, subfamily A, polypeptide 1 (cyp19a1) 抗体
  • Ar 抗体
  • ArKO 抗体
  • aro 抗体
  • ARO1 抗体
  • Aromatase 抗体
  • CPV1 抗体
  • CYAR 抗体
  • cyp19 抗体
  • cyp19a 抗体
  • CYP19A1 抗体
  • CYP19P1 抗体
  • CYPXIX 抗体
  • Int-5 抗体
  • Int5 抗体
  • P-450AROM 抗体
  • P450 arom 抗体
  • P450AROM 抗体
  • p450arom-A 抗体

Protein level used designations for CYP19A1

aromatase , cytochrome P450 aromatase , CYPXIXA1 , cytochrome P-450AROM , cytochrome P450 19 type I , cytochrome P450, family19, subfamily A, polypeptide 1 , estrogen synthase , CYPXIXA3 , aromatase cytochrome P450 , cytochrome P450 19 type III , cytochrome P450, family 19, subfamily A, polypeptide 3 , type I cytochrome p450 aromatase , CYPXIX , cytochrome P450 19A1 , estrogen synthetase , cytochrome P450, subfamily XIX (aromatization of androgens) , flavoprotein-linked monooxygenase , microsomal monooxygenase , Cytochrome P450, 19, aromatase , P-450AROM , cytochrome P450 family 19 subfamily a , cytochrome P450, subfamily 19 , cytochrome P450, family XIX (conversion of androgen to estrogen), aromatase , cytochrome P450, 19, aromatase , cytochrome P450 17-alpha , Cytochrome P-450AROM , Cytochrome P450 19A1 , Estrogen synthase , p450 aromatase A

GENE ID SPECIES
1213743 Streptomyces avermitilis MA-4680
100379639 Takifugu rubripes
403331 Sus scrofa
403333 Sus scrofa
494003 Canis lupus familiaris
100144423 Ovis aries
414854 Gallus gallus
1588 Homo sapiens
25147 Rattus norvegicus
281740 Bos taurus
13075 Mus musculus
100009712 Equus caballus
100328545 Oryctolagus cuniculus
100861413 Capra hircus
373656 Xenopus laevis
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