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anti-RAB8A (RAB8A) 抗体产品概述

Full name:
anti-RAB8A, Member RAS Oncogene Family 抗体 (RAB8A)
在www.antibodies-online.cn可供84 RAB8A, Member RAS Oncogene Family (RAB8A) 抗体的18不同的供货商。 再加上,我们可以发RAB8A 蛋白 (16)RAB8A 试剂盒 (9)和数多这个蛋白质的别的产品。 总共113 RAB8A产品已列进来了。
别名:
AA409338, c-mel, DDBDRAFT_0206521, DDBDRAFT_0214885, DDB_0206521, DDB_0214885, HSH2D, Mel, Rab8, rab8A, zgc:162699

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引用最多的anti-RAB8A 抗体

  1. Dog (Canine) Monoclonal RAB8A Primary Antibody for IF, IP - ABIN968210 : Bahadoran, Aberdam, Mantoux, Buscà, Bille, Yalman, de Saint-Basile, Casaroli-Marano, Ortonne, Ballotti: Rab27a: A key to melanosome transport in human melanocytes. in The Journal of cell biology 2001 (PubMed)
    Show all 5 references for ABIN968210

  2. Human Polyclonal RAB8A Primary Antibody for FACS, IHC (p) - ABIN1881723 : Kato, Sekine, Oh, Kim, Umezawa, Abe, Yokoyama-Kobayashi, Aoki: Construction of a human full-length cDNA bank. in Gene 1995 (PubMed)
    Show all 2 references for ABIN1881723

  3. Cow (Bovine) Polyclonal RAB8A Primary Antibody for ELISA, WB - ABIN374945 : Yoshimura, Egerer, Fuchs, Haas, Barr: Functional dissection of Rab GTPases involved in primary cilium formation. in The Journal of cell biology 2007 (PubMed)

  4. Cow (Bovine) Polyclonal RAB8A Primary Antibody for WB - ABIN2792290 : Roland, Kenworthy, Peranen, Caplan, Goldenring: Myosin Vb interacts with Rab8a on a tubular network containing EHD1 and EHD3. in Molecular biology of the cell 2007 (PubMed)

更多抗RAB8A的相互作用对抗体

Human RAB8A, Member RAS Oncogene Family (RAB8A) interaction partners

  1. report the design of a bioavailable StRIP3 analogue that harbors two hydrophobic cross-links and exhibits increased binding affinity, combined with robust cellular uptake and extremely high proteolytic stability. Localization experiments reveal that this double-stapled peptide and its target protein Rab8a accumulate in the same cellular compartments

  2. knockdown of another Parkinson's disease (PD) gene, LRRK2 (显示 LRRK2 抗体), which phosphorylates Rab8a, similarly impairs retromer trafficking, secretory autophagy and Golgi-derived vesicle secretion, thus demonstrating converging roles of two PD genes TMEM230 and LRRK2 (显示 LRRK2 抗体) on Rab8a function, and suggesting that retromer and secretory dysfunction play an important role in PD pathogenesis.

  3. Rab8 can induce Rac1- and Tiam1 (显示 TIAM1 抗体)-dependent cortical actin polymerization and focal adhesion disassembly through the proteases MT1-MMP (显示 MMP14 抗体) and calpain, and Rho-GTPase (显示 RACGAP1 抗体)-dependent mechanisms

  4. Data demonstrate that EHBP1L1 links Rab8 and the Bin1 (显示 BIN1 抗体)-dynamin (显示 DNM1 抗体) complex, which generates membrane curvature and excises the vesicle at the endocytic recycling compartment for apical transport.

  5. Further exploration of the NINL (显示 NINL 抗体)-associated interactome identifies MICAL3 (显示 MICAL3 抗体), a protein known to interact with Rab8 and to play an important role in vesicle docking and fusion.

  6. The small GTPase (显示 RACGAP1 抗体) Rab8 interacts with VAMP-3 (显示 VAMP3 抗体) to regulate the delivery of recycling T-cell receptors to the immune synapse.

  7. the role of Rabin8 (显示 RAB3IP 抗体) (a mammalian ortholog of Sec2p) with Rab8-nucleotide-exchange factor activity in autophagy in mammalian cells, was examined.

  8. DLC3 (显示 STARD8 抗体) is recruited to Rab8-positive membrane tubules and is required for the integrity of the Rab8 and Golgi compartments.

  9. Rab8A GTPase (显示 RACGAP1 抗体) Ser (显示 SIGLEC1 抗体)(111) phosphorylation is not directly regulated by PINK1 (显示 PINK1 抗体) in vitro and demonstrate in cells the time course of Ser (显示 SIGLEC1 抗体)(111) phosphorylation of Rab8A, 8B and 13 is markedly delayed compared to phosphorylation of Parkin (显示 PARK2 抗体) at Ser (显示 SIGLEC1 抗体)(65).

  10. Intercellular transfer of transferrin receptor by a contact-, Rab8-dependent mechanism involving tunneling nanotubes.

Zebrafish RAB8A, Member RAS Oncogene Family (RAB8A) interaction partners

  1. Cc2d2a (显示 CC2D2A 抗体), localized at the photoreceptor connecting cilium/transition zone, facilitates protein transport through a role in Rab8-dependent vesicle trafficking and fusion.

  2. Data show that elipsa (显示 TRAF3IP1 抗体) encodes a coiled-coil polypeptide that localizes to cilia, and that it interacts genetically with Rabaptin5, a well-studied regulator of endocytosis, which in turn interacts with Rab8, a small GTPase (显示 RACGAP1 抗体), known to localize to cilia.

Mouse (Murine) RAB8A, Member RAS Oncogene Family (RAB8A) interaction partners

  1. With CRISPR/Cas9-mediated gene editing to stably knock out and recover Rab8a in macrophage cell lines, this study matches Akt (显示 AKT1 抗体) signaling profiles with cytokine outputs, confirming that Rab8a is a novel regulator of the Akt (显示 AKT1 抗体)/mammalian target of rapamycin (mTOR (显示 FRAP1 抗体)) pathway downstream of multiple Toll (显示 TLR4 抗体)-like Receptors.

  2. these results indicate an indispensable role for Rab8A in insulin (显示 INS 抗体)-regulated GLUT4 (显示 SLC2A4 抗体) trafficking in C2C12 cells.

  3. Results highlight a novel role of Rab8, downstream of IFT20, in the pathway that regulates T cell receptor (TCR) recycling, through recruiting VAMP-3 and promoting the fusion with the synaptic membrane of endosomes carrying TCR cargoes.

  4. Data demonstrate that EHBP1L1 links Rab8 and the Bin1 (显示 BIN1 抗体)-dynamin (显示 DNM1 抗体) complex, which generates membrane curvature and excises the vesicle at the endocytic recycling compartment for apical transport.

  5. The small GTPase (显示 RACGAP1 抗体) Rab8 interacts with VAMP-3 (显示 VAMP3 抗体) to regulate the delivery of recycling T-cell receptors to the immune synapse.

  6. Rab8a thus controls Wnt (显示 WNT2 抗体) delivery in producing cells and is crucial for Paneth cell maturation.

  7. Rab8a acts as an activator of Fsp27 (显示 CIDEC 抗体)-mediated LD fusion and growth.

  8. Simultaneous loss of Rab8a and Rab8b (显示 RAB8B 抗体) has little effect on ciliogenesis, whereas additional loss of Rab10 (显示 RAB10 抗体) greatly affects ciliogenesis.

  9. acidosis-induced NBCe1 (显示 SLC4A4 抗体)-A, but not NBCe1 (显示 SLC4A4 抗体)-B/C, trafficking is mediated by Rab8a.

  10. AS160 (显示 TBC1D4 抗体) and Rab8a regulate membrane recruitment of CD36 (显示 CD36 抗体).

RAB8A 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.

Alternative names and synonyms associated with RAB8A

  • rab8A protein (rab8A) 抗体
  • Rab GTPase (rab8A) 抗体
  • RAB8A, member RAS oncogene family (RAB8A) 抗体
  • RAB8A, member RAS oncogene family (rab8a) 抗体
  • RAB8A, member RAS oncogene family (Rab8a) 抗体
  • AA409338 抗体
  • c-mel 抗体
  • DDBDRAFT_0206521 抗体
  • DDBDRAFT_0214885 抗体
  • DDB_0206521 抗体
  • DDB_0214885 抗体
  • HSH2D 抗体
  • Mel 抗体
  • Rab8 抗体
  • rab8A 抗体
  • zgc:162699 抗体

Protein level used designations for RAB8A

rab8A protein , hematopoietic SH2 domain containing , ras-related protein Rab-8A , RAB8A, member RAS oncogene family , member RAS oncogene family , Ras-related protein Rab-8A , mel transforming oncogene (RAB8 homolog) , mel transforming oncogene (derived from cell line NK14) , mel transforming oncogene (derived from cell line NK14)- RAB8 homolog , oncogene c-mel , ras-associated protein RAB8 , RAB8, member RAS oncogene family , cell line NK14 derived transforming oncogene

GENE ID SPECIES
553899 Lotus japonicus
8622514 Dictyostelium discoideum AX4
468760 Pan troglodytes
100125217 Xenopus (Silurana) tropicalis
100380328 Salmo salar
4218 Homo sapiens
403773 Canis lupus familiaris
100125881 Bos taurus
571897 Danio rerio
100037230 Xenopus laevis
428352 Gallus gallus
17274 Mus musculus
117103 Rattus norvegicus
100174026 Pongo abelii
101092668 Felis catus
100511006 Sus scrofa
100302063 Ovis aries
100734132 Cavia porcellus
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