Complement Factor H 抗体
(Complement Factor H (CFH))
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011].
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102 results
Independently Validated
CFH
适用: 大鼠
WB, IHC
宿主: 小鼠
Monoclonal
C3
unconjugated
1 image
CFH
适用: 人
WB, ELISA, FACS, IHC (fro)
宿主: 小鼠
Monoclonal
10-10
unconjugated
1 reference
CFH
适用: 人, 大鼠, 小鼠
WB, IHC (p), IF (p)
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our Complement Factor H 抗体
: "HK2 Mediated Glycolytic Metabolism in Mouse Photoreceptors Is Not Required to Cause Late Stage Age-Related Macular Degeneration-Like Pathologies." in: Biomolecules, Vol. 11, Issue 6, (2021) (PubMed).: "The role of anti-complement factor H antibodies in the development of atypical haemolytic uremic syndrome: a possible contribution to abnormality of platelet function." in: British journal of haematology, Vol. 189, Issue 1, pp. 182-186, (2020) (PubMed).
: "Factor H Binds to Extracellular DNA Traps Released from Human Blood Monocytes in Response to Candida albicans." in: Frontiers in immunology, Vol. 7, pp. 671, (2016) (PubMed).
: "Design and evaluation of meningococcal vaccines through structure-based modification of host and pathogen molecules." in: PLoS pathogens, Vol. 8, Issue 10, pp. e1002981, (2013) (PubMed).
: "Complement system dysregulation and inflammation in the retinal pigment epithelium of a mouse model for Stargardt macular degeneration." in: The Journal of biological chemistry, Vol. 286, Issue 21, pp. 18593-601, (2011) (PubMed).
: "Impact of compound heterozygous complement factor H mutations on development of atypical hemolytic uremic syndrome-A pedigree revisited." in: Molecular immunology, Vol. 47, Issue 7-8, pp. 1585-91, (2010) (PubMed).
: "Heparan sulfate, including that in Bruch's membrane, inhibits the complement alternative pathway: implications for age-related macular degeneration." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 9, pp. 5486-94, (2010) (PubMed).
: "The simple design of complement factor H: Looks can be deceiving." in: Molecular immunology, Vol. 44, Issue 1-3, pp. 123-32, (2006) (PubMed).
: "Complement factor H polymorphism in age-related macular degeneration." in: Science (New York, N.Y.), Vol. 308, Issue 5720, pp. 385-9, (2005) (PubMed).
: "The human complement factor H: functional roles, genetic variations and disease associations." in: Molecular immunology, Vol. 41, Issue 4, pp. 355-67, (2004) (PubMed).
Aliases for Complement Factor H 抗体
complement factor H (CFH) 抗体complement component factor h (Cfh) 抗体
complement factor H (Cfh) 抗体
complement factor H (cfh) 抗体
complement factor H-related protein 5 (LOC100399888) 抗体
complement factor H (LOC100733902) 抗体
complement factor H L homeolog (cfh.L) 抗体
AHUS1 抗体
AMBP1 抗体
ARMD4 抗体
armd4 抗体
ARMS1 抗体
arms1 抗体
CFH 抗体
cfh 抗体
CFHL3 抗体
cfhl3 抗体
FH 抗体
Fh 抗体
fH 抗体
FHL1 抗体
fhl1 抗体
HF 抗体
HF1 抗体
hf1 抗体
HF2 抗体
hf2 抗体
HUS 抗体
hus 抗体
im:7147412 抗体
Mud-1 抗体
NOM 抗体
Sas-1 抗体
Sas1 抗体
si:ch211-207o17.2 抗体
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