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SMAD4 蛋白

(SMAD Family Member 4 (SMAD4))
This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Oct 2009].
SMAD4 Protein (AA 1-552) (GST tag) SMAD4 Protein (AA 1-552) (GST tag) SMAD4 Protein (AA 1-552) (GST tag) (ABIN1320605)

SMAD4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

SMAD4 Protein (AA 13-227) (His tag) SMAD4 Protein (AA 13-227) (His tag) SMAD4 Protein (AA 13-227) (His tag) (ABIN7125119)

SMAD4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

SMAD4 Protein (AA 56-165) (GST tag) SMAD4 Protein (AA 56-165) (GST tag) SMAD4 Protein (AA 56-165) (GST tag) (ABIN1320607)

SMAD4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

SMAD4 蛋白 by Grade

Find SMAD4 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SMAD4 蛋白 by Origin

Find SMAD4 蛋白 for a variety of species such as anti-Human SMAD4, anti-Mouse SMAD4, anti-Rat SMAD4. The species listed below are among those available. Click on a link to go to the corresponding products.

SMAD4 蛋白 by Source

Here you will find SMAD4 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

SMAD4 蛋白 by 蛋白类型

Here you can find SMAD4 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

SMAD4 蛋白 by 应用范围

Find SMAD4 蛋白 validated for a specific application such as WB, ELISA, SDS, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular SMAD4 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1320605
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125119
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320607
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3095493
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134713
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2732222
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7319042
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7395287
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7413811
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1692097
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2751533
Quantity 5 applications
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6700538
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1475622
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SMAD4 蛋白

Atanelishvili, Shirai, Akter, Buckner, Noguchi, Silver, Bogatkevich: "M10, a caspase cleavage product of the hepatocyte growth factor receptor, interacts with Smad2 and demonstrates antifibrotic properties in vitro and in vivo." in: Translational research : the journal of laboratory and clinical medicine, Vol. 170, pp. 99-111, (2016) (PubMed).

Iempridee, Das, Xu, Mertz: "Transforming growth factor beta-induced reactivation of Epstein-Barr virus involves multiple Smad-binding elements cooperatively activating expression of the latent-lytic switch BZLF1 gene." in: Journal of virology, Vol. 85, Issue 15, pp. 7836-48, (2011) (PubMed).

Aliases for SMAD4 蛋白

SMAD family member 4 (SMAD4) 蛋白
Smad4 protein (smad4) 蛋白
SMAD family member 4 (Smad4) 蛋白
SMAD family member 4, gene 1 L homeolog (smad4.1.L) 蛋白
AW743858 蛋白
D18Wsu70e 蛋白
DPC4 蛋白
dpc4 蛋白
JIP 蛋白
jip 蛋白
MADH4 蛋白
Madh4 蛋白
madh4 蛋白
MYHRS 蛋白
smad4 蛋白
Xsmad4 蛋白
xsmad4a 蛋白
XSmad4alpha 蛋白
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