anti-LIM Domain Kinase 1 (LIMK1) 抗体产品概述

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anti-LIM Domain Kinase 1 抗体 (LIMK1)
在www.antibodies-online.cn可供220 LIM Domain Kinase 1 (LIMK1) 抗体的26不同的供货商。 再加上,我们可以发LIM Domain Kinase 1 蛋白 (11)LIM Domain Kinase 1 试剂盒 (2)和数多这个蛋白质的别的产品。 总共242 LIM Domain Kinase 1产品已列进来了。
别名:
GB16654, LIMK, LIMK-1, LIMK1, xlimk1
列出全部抗体 基因 基因ID UniProt
LIMK1 3984 P53667
LIMK1 65172  
LIMK1 16885 P53668

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引用最多的anti-LIM Domain Kinase 1 抗体

  1. Human Polyclonal LIM Domain Kinase 1 Primary Antibody for EIA, IHC (p) - ABIN360142 : Ohashi, Nagata, Maekawa, Ishizaki, Narumiya, Mizuno: Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop. in The Journal of biological chemistry 2000 (PubMed)
    Show all 5 references for 360142

  2. Human Monoclonal LIM Domain Kinase 1 Primary Antibody for IF, WB - ABIN968654 : Edwards, Gill: Structural features of LIM kinase that control effects on the actin cytoskeleton. in The Journal of biological chemistry 1999 (PubMed)
    Show all 4 references for 968654

  3. Human Polyclonal LIM Domain Kinase 1 Primary Antibody for IHC (p), WB - ABIN392258 : Maekawa, Ishizaki, Boku, Watanabe, Fujita, Iwamatsu, Obinata, Ohashi, Mizuno, Narumiya: Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. in Science (New York, N.Y.) 1999 (PubMed)
    Show all 4 references for 392258

  4. Human Polyclonal LIM Domain Kinase 1 Primary Antibody for ELISA, WB - ABIN1533778 : Mizuno, Okano, Ohashi, Nunoue, Kuma, Miyata, Nakamura: Identification of a human cDNA encoding a novel protein kinase with two repeats of the LIM/double zinc finger motif. in Oncogene 1994 (PubMed)
    Show all 3 references for 1533778

  5. Human Polyclonal LIM Domain Kinase 1 Primary Antibody for IF, IHC (p) - ABIN196830 : Edwards, Sanders, Bokoch, Gill: Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics. in Nature cell biology 1999 (PubMed)
    Show all 2 references for 196830

  6. Human Polyclonal LIM Domain Kinase 1 Primary Antibody for ICC, IF - ABIN4330977 : Gupta, Yadav, Pavuluri, Morley, Stairs, Dravid: Essential role of GluD1 in dendritic spine development and GluN2B to GluN2A NMDAR subunit switch in the cortex and hippocampus reveals ability of GluN2B inhibition in correcting hyperconnectivity. in Neuropharmacology 2015 (PubMed)

更多抗LIM Domain Kinase 1的相互作用对抗体

Human LIM Domain Kinase 1 (LIMK1) interaction partners

  1. Report structural basis for noncanonical substrate recognition of cofilin-1/LIMK1 to regulation actin cytoskeleton dynamics.

  2. LIMK1 expression is negatively regulated in granular layers-negative psoriatic epidermis or IL-22 (显示 IL22 抗体)/IL-24 (显示 IL24 抗体)-treated hyperproliferative reconstituted epidermis. These findings suggest a novel regulatory mechanism and a potent role of LIMK1 in psoriatic epidermis.

  3. Therefore, miR (显示 MLXIP 抗体)-138/LIMK1/cofilin (显示 CFL1 抗体) may be considered a potential therapeutic target for the treatment of non-small cell lung cancer

  4. This study showed that LIMK1 messenger RNA levels was significantly upregulated in subjects with schizophrenia in laminar and cellular samples.

  5. Gene knockdown/rescue experiments reveal that LIMK1 palmitoylation is essential for normal spine actin polymerization, for spine-specific structural plasticity and for long-term spine stability.

  6. LIMK1 is overexpressed in endometrial stromal cells.

  7. Data show that the downregulation of miR (显示 MLXIP 抗体)-138 induced the upregulation of Limk1 in ovarian cancer (OC) cells suggesting that these 2 genes may play a key role in the migration and invasion of OC cells.

  8. LIMK1 is overexpressed in gastric cancer.

  9. Results show that in addition to a potential role in promoting metastasis, changes in LIMK1 and LIMK2 (显示 LIMK2 抗体) expression and/or activity might contribute to AR function in prostate cancer via regulation of microtubule cytoskeletal dynamics.

  10. CXCL12 (显示 CXCL12 抗体)/CXCR4 (显示 CXCR4 抗体) signaling has a role in docetaxel-induced microtubule stabilization via p21-activated kinase 4 (显示 PAK4 抗体)-dependent activation of LIMK1

Xenopus laevis LIM Domain Kinase 1 (LIMK1) interaction partners

  1. bone morphogenetic protein receptor II (BMPRII (显示 BMPR2 抗体)) is a major regulator of LIMK1 in extending RGC axons, as expression of a BMPRII (显示 BMPR2 抗体) lacking the LIMK1 binding region caused a dramatic shortening of the axons

Mouse (Murine) LIM Domain Kinase 1 (LIMK1) interaction partners

  1. LIMK1 negatively regulated neuronal migration by affecting the neuronal cytoskeleton and that its effects were partly mediated by cofilin (显示 CFL1 抗体) phosphorylation

  2. Social isolation resulted in up-regulation of Limk-1 mRNA expression in the cerebral cortex.

  3. The data emphasize the importance of the PLCeta2 EF-hand domain and articulation of PLCeta2 with LIMK-1 in regulating neuritogenesis.

  4. Our study indicates that there is a connection between LIMK1 and AD in the mouse model of AD.

  5. Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization.

  6. LIMK1 and Cofilin (显示 CFL1 抗体) phosphorylation depends on PKA and is essential for mouse sperm acrosomal exocytosis

  7. These results provide strong evidence that LIMK1 deletion is sufficient to lead to a long-term memory deficit and that this deficit is attributable to CREB (显示 CREB1 抗体) hypofunction.

  8. the conserved region in the LIMK1 3' UTR (显示 UTS2R 抗体) is involved in regulating LIMK1 expression at the post-transcriptional level

  9. LIMK1 plays a novel role in selectively mediating GPIb-IX-dependent TXA2 (显示 TBXA2R 抗体) synthesis and thrombosis.

  10. data support the hypothesis that LIMK1 is required for normal osteoblast differentiation. In addition, its absence leads to increased cytoskeletal remodeling and bone resorption in osteoclasts

LIM Domain Kinase 1 (LIMK1) 抗原简介

Antigen Summary

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure. This protein also stimulates axon growth and may play a role in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Alternative names and synonyms associated with LIM Domain Kinase 1 (LIMK1)

  • LIM domain kinase 1 (LIMK1) 抗体
  • LIM domain kinase 1a (limk1a) 抗体
  • LIM domain kinase 1 (limk1) 抗体
  • LIM domain kinase 1 (CpipJ_CPIJ000717) 抗体
  • LIM-kinase1 (LIMK1) 抗体
  • LIM domain kinase 1 (Limk1) 抗体
  • LIM-domain containing, protein kinase (Limk1) 抗体
  • GB16654 抗体
  • LIMK 抗体
  • LIMK-1 抗体
  • LIMK1 抗体
  • xlimk1 抗体

Protein level used designations for anti-LIM Domain Kinase 1 (LIMK1) 抗体

LIM domain kinase 1 , LIM-kinase1 , LIM motif-containing protein kinase , LIM motif-containing protein kinase 1 , LIM-domain containing protein kinase 1 , LIM-domain containing, protein kinase 1 , LIMK-1 , chLIMK1 , KIZ-1

GENE ID SPECIES
489800 Canis lupus familiaris
100062100 Equus caballus
735292 Danio rerio
780362 Xenopus (Silurana) tropicalis
6031483 Culex quinquefasciatus
413152 Apis mellifera
100286874 Sus scrofa
3984 Homo sapiens
65172 Rattus norvegicus
463466 Pan troglodytes
100294566 Pongo abelii
535225 Bos taurus
373922 Gallus gallus
397696 Xenopus laevis
16885 Mus musculus
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