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- 抗原 See all CCL2 抗体
- CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
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适用
- 人
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克隆类型
- 单克隆
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标记
- This CCL2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- Ni-NTA purified recombinant human MCP-1 expressed in E.Coli strain BL21 (DE3).
- 纯化方法
- Antibodies are purified by protein A affinity chromatography
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CCL2 Primary Antibody
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- 应用备注
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Dilution: Western Blot: 1:500-1,000
ELISA: 1,000-2,000. - 限制
- 仅限研究用
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- 储存条件
- -20 °C
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Human monocyte chemoattractant protein-1 (MCP-1)." in: Advances in experimental medicine and biology, Vol. 305, pp. 47-56, (1992) (PubMed).
: "Assignment of the human small inducible cytokine A2 gene, SCYA2 (encoding JE or MCP-1), to 17q11.2-12: evolutionary relatedness of cytokines clustered at the same locus." in: Genomics, Vol. 10, Issue 2, pp. 489-92, (1991) (PubMed).
: "Human monocyte chemoattractant protein-1 (MCP-1). Full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE." in: FEBS letters, Vol. 244, Issue 2, pp. 487-93, (1989) (PubMed).
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Human monocyte chemoattractant protein-1 (MCP-1)." in: Advances in experimental medicine and biology, Vol. 305, pp. 47-56, (1992) (PubMed).
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- 抗原
- CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
- 别名
- MCP-1 (CCL2 产品)
- 别名
- GDCF-2 antibody, HC11 antibody, HSMCR30 antibody, MCAF antibody, MCP-1 antibody, MCP1 antibody, SCYA2 antibody, SMC-CF antibody, AI323594 antibody, JE antibody, Scya2 antibody, Sigje antibody, MCP-1A antibody, MCP1A antibody, C-C motif chemokine ligand 2 antibody, chemokine (C-C motif) ligand 2 antibody, C-C motif chemokine 2 antibody, CCL2 antibody, Ccl2 antibody, LOC101120093 antibody
- 背景
- Monocyte chemoattractant protein-1 (MCP-1) is a member of the chemokine-beta family of cytokines. The protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. It may play a inprotant role in the initiation and/or progression of pulmonary hypertension (PH). Blockade of a systemic MCP-1 signal pathway in vivo may prevent PH.
- 途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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