(2 references)-
- 抗原 See all EDEM1 抗体
- EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EDEM1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 纯化方法
- Purified by antigen-specific affinity chromatography.
- 免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human EDEM1(ER degradation-enhancing alpha-mannosidase-like 1)
- Top Product
- Discover our top product EDEM1 Primary Antibody
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anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 559-656) antibody
EDEM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D3 unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 46-128) antibodyEDEM1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (C-Term) antibodyEDEM1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 146-195) antibodyEDEM1 适用: 人, 小鼠, 兔, Cow, 猴, Pig, 豚鼠, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (N-Term) antibodyEDEM1 适用: 人, 小鼠, 兔, Cow, 大鼠, 豚鼠, 犬, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (Center) antibodyEDEM1 适用: 人, 小鼠, 兔, Cow, 大鼠, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- ELISA, Western blotting: 1µg/ml for 2hrs.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- This antibody is stored in PBS, 50% glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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: "Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle." in: Science (New York, N.Y.), Vol. 299, Issue 5611, pp. 1397-400, (2003) (PubMed).
: "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 3, Issue 5, pp. 321-9, 341-54, (1997) (PubMed).
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: "Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle." in: Science (New York, N.Y.), Vol. 299, Issue 5611, pp. 1397-400, (2003) (PubMed).
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- 抗原
- EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))
- 别名
- EDEM1 (EDEM1 产品)
- 别名
- zgc:55816 antibody, edem antibody, EDEM1 antibody, EDEM antibody, A130059K23Rik antibody, mKIAA0212 antibody, RGD1563633 antibody, ER degradation enhancer, mannosidase alpha-like 1 antibody, ER degradation enhancing alpha-mannosidase like protein 1 antibody, ER degradation-enhancing alpha-mannosidase-like protein 1 antibody, ER degradation enhancing alpha-mannosidase like protein 1 L homeolog antibody, edem1 antibody, EDEM1 antibody, LOC100637820 antibody, edem1.L antibody, Edem1 antibody
- 背景
- EDEM1(ER degradation-enhancing alpha-mannosidase-like 1) extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity. EDEM1 is located in endoplasmic reticulum membrane and is a single-pass type II membrane protein. EDEM1 belongs to the glycosyl hydrolase 47 family.
- 途径
- ER-Nucleus Signaling
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