EDEM1 抗体 (N-Term)
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- 抗原 See all EDEM1 抗体
- EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, Cow, 兔, 大鼠, 豚鼠, 犬, Saccharomyces cerevisiae
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EDEM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MAHAFPQDEL NPIHCRGRGP DRGDPSNLNI NDVLGNYSLT LVDALDTLAI
- 预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%
- 产品特性
- This is a rabbit polyclonal antibody against EDEM1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human EDEM1
- Top Product
- Discover our top product EDEM1 Primary Antibody
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anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 559-656) antibody
EDEM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D3 unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 46-128) antibodyEDEM1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (C-Term) antibodyEDEM1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 146-195) antibodyEDEM1 适用: 人, 小鼠, Cow, 兔, 猴, Pig, 豚鼠, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (Center) antibodyEDEM1 适用: 人, 小鼠, Cow, 兔, 大鼠, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 657 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))
- 别名
- EDEM1 (EDEM1 产品)
- 别名
- zgc:55816 antibody, edem antibody, EDEM1 antibody, EDEM antibody, A130059K23Rik antibody, mKIAA0212 antibody, RGD1563633 antibody, ER degradation enhancer, mannosidase alpha-like 1 antibody, ER degradation enhancing alpha-mannosidase like protein 1 antibody, ER degradation-enhancing alpha-mannosidase-like protein 1 antibody, ER degradation enhancing alpha-mannosidase like protein 1 L homeolog antibody, edem1 antibody, EDEM1 antibody, LOC100637820 antibody, edem1.L antibody, Edem1 antibody
- 背景
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EDEM1 belongs to the glycosyl hydrolase 47 family. It extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner.
Alias Symbols: EDEM, KIAA0212
Protein Interaction Partner: HLA-B, SQSTM1, UBC, MMS19, SSR1, ASGR1, DERL1, DNAJC10, DERL2, SEC61B, SEL1L, RHO, CANX, RCOM_2159910, ASGR2, ELAVL1, BZW1,
Protein Size: 657 - 分子量
- 74 kDa
- 基因ID
- 9695
- NCBI登录号
- NM_014674, NP_055489
- UniProt
- Q92611
- 途径
- ER-Nucleus Signaling
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