EDEM1 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for EDEM1 抗体 (N-Term) (ABIN2782826)
抗原
See all EDEM1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
原理
- EDEM1 Antibody - N-terminal region
-
序列
- MAHAFPQDEL NPIHCRGRGP DRGDPSNLNI NDVLGNYSLT LVDALDTLAI
-
预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%
-
产品特性
- This is a rabbit polyclonal antibody against EDEM1. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human EDEM1
-
-
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 559-656) antibody
EDEM1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2D3 unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 146-195) antibodyEDEM1 适用: 人, 小鼠, Cow, 兔, 猴, Pig, 豚鼠, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (C-Term) antibodyEDEM1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 46-128) antibodyEDEM1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (N-Term) antibodyEDEM1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47054-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))
-
别名
- EDEM1
-
背景
-
Background Information: EDEM1 belongs to the glycosyl hydrolase 47 family. It extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner.
Gene Name: ER degradation enhancer, mannosidase alpha-like 1
Alternative Symbols: EDEM
Protein Name: ER degradation-enhancing alpha-mannosidase-like 1
-
分子量
- 74kDa
-
基因ID
- 9695
-
NCBI登录号
- NP_055489
-
UniProt
- Q92611
-
途径
- ER-Nucleus Signaling
抗原
-
