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MDS1 and EVI1 Complex Locus (MECOM) (AA 1-30), (N-Term) 抗体

ABIN952135 产品详细信息, 供应商: Log in to see
抗原
  • evi1
  • im:7140716
  • prdm3
  • EVI1
  • AML1-EVI-1
  • MDS1
  • MDS1-EVI1
  • PRDM3
  • D630039M04Rik
  • Evi-1
  • Evi1
  • Jbo
  • Mds
  • Mds1
  • Mds1-Evi1
  • Prdm3
  • Znfpr1b1
  • AML1
  • AMLCR1
  • CBFA2
  • EVI-1
  • PEBP2aB
  • MDS1 and EVI1 complex locus
  • runt-related transcription factor 1
  • mecom
  • MECOM
  • LOC100343228
  • Mecom
  • RUNX1
抗原表位
N-Term, AA 1-30
28
17
16
15
9
5
5
4
4
3
3
2
2
2
1
1
1
1
1
适用

105
34
9
4
4
3
3
2
1
1
1
宿主

71
31
15
克隆类型
多克隆
标记
非结合性
6
6
6
6
6
6
应用范围
Enzyme Immunoassay (EIA), Western Blotting (WB)
104
65
11
5
3
2
1
1
1
1
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免疫原 KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of Human EVI1. Genename: MECOM
亚型 Ig
特异性 This antibody recognizes Human EVI1 (N-term).
纯化方法 Affinity Chromatography on Protein A
别名 EVI1 (MECOM Antibody 摘要)
背景 EVI1 functions as a transcriptional regulator binding to DNA sequences in the promoter region of target genes and regulating positively or negatively their expression. Oncogene which plays a role in development, cell proliferation and differentiation. May also play a role in apoptosis through regulation of the JNK and TGF-beta signaling. Involved in hematopoiesis.Synonyms: EVI-1, Ecotropic virus integration site 1 protein homolog, MDS1 and EVI1 complex locus protein EVI1, MECOM
分子量 118276 Da
基因ID 2122
NCBI登录号 NP_001098547
研究领域 Chromatin and Nuclear Signaling, Chromatin Binding Proteins, Cell Cycle
应用备注 Optimal working dilution should be determined by the investigator.
限制 仅限研究用
状态 Liquid
浓度 0.25 mg/mL
缓冲液 PBS containing 0.09 % (W/V) Sodium Azide as preservative
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
厂商提供的图像
Western Blotting (WB) image for anti-MDS1 and EVI1 Complex Locus (MECOM) (AA 1-30), (N-Term) 抗体 (ABIN952135) Western blot analysis of EVI1 Antibody (N-term) in CEM cell line lysates (35ug/lane)....
背景 Gómez-Benito, Conchillo, García, Vázquez, Maicas, Vicente, Cristobal, Marcotegui, García-Ortí, Bandrés, Calasanz, Alonso, Odero: "EVI1 controls proliferation in acute myeloid leukaemia through modulation of miR-1-2." in: British journal of cancer, Vol. 103, Issue 8, pp. 1292-6, 2010 (PubMed).

Goyama, Kurokawa: "Evi-1 as a critical regulator of leukemic cells." in: International journal of hematology, Vol. 91, Issue 5, pp. 753-7, 2010 (PubMed).