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- 抗原 See all Caspase 3 (CASP3) 抗体
- Caspase 3 (CASP3)
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抗原表位
- AA 29-33
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Caspase 3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- The antibody detects endogenous level of total Caspase 3 protein.
- 纯化方法
- Affinity purified
- 免疫原
- Peptide sequence around AA 29-33 (S-G-I-S-L) derived from Caspase 3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Top Product
- Discover our top product CASP3 Primary Antibody
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- 应用备注
- Western blotting: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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The use of hollow mesoporous silica nanospheres to encapsulate bortezomib and improve efficacy for non-small cell lung cancer therapy." in: Biomaterials, Vol. 35, Issue 1, pp. 316-26, (2013) (PubMed).
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The use of hollow mesoporous silica nanospheres to encapsulate bortezomib and improve efficacy for non-small cell lung cancer therapy." in: Biomaterials, Vol. 35, Issue 1, pp. 316-26, (2013) (PubMed).
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- 抗原
- Caspase 3 (CASP3)
- 别名
- Caspase 3 (CASP3 产品)
- 别名
- CPP32 antibody, CPP32B antibody, SCA-1 antibody, A830040C14Rik antibody, AC-3 antibody, Apopain antibody, CC3 antibody, Caspase-3 antibody, Lice antibody, Yama antibody, mldy antibody, xcpp32 antibody, casp3 antibody, zgc:100890 antibody, CASP-3 antibody, caspase-3 antibody, caspase 3 antibody, caspase 3 S homeolog antibody, caspase 3, apoptosis-related cysteine peptidase a antibody, caspase 3, apoptosis-related cysteine peptidase antibody, CASP3 antibody, Casp3 antibody, casp3.S antibody, casp3a antibody
- 背景
- Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
- 分子量
- 17 kDa
- 基因ID
- 836
- NCBI登录号
- NP_004337
- UniProt
- P42574
- 途径
- Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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