DOC2A 抗体 (Double C2-Like Domains, alpha) (AA 277-306)

Details for Product anti-DOC2A Antibody No. ABIN656766, 供应商: Log in to see
抗原
  • DOC2A
  • doc2-A
  • Doc2
  • double C2-like domains, alpha
  • double C2, alpha
  • DOC2A
  • doc2a
  • Doc2a
抗原表位
AA 277-306, Center
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克隆类型 (克隆位点)
多克隆 ()
标记
This DOC2A antibody is un-conjugated
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应用范围
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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选项
Supplier
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Supplier Product No.
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免疫原 This DOC2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 AA from the Central region of human DOC2A.
克隆位点 RB32573
亚型 Ig
特异性 This DOC2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-314 amino acids from the Central region of human DOC2A.
预测反应 Mouse (Murine),Rat (Rattus)
纯化方法 This antibody is purified through a protein A column, followed by peptide affinity purification.
别名 DOC2A (DOC2A Antibody 摘要)
背景 There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes, these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release.
Synonyms: Double C2-like domain-containing protein alpha,DOC2A,
分子量 43959 DA
基因ID 8448
NCBI登录号 NP_003577
UniProt Q14183
研究领域 Cell Structure, Neurology
途径 Synaptic Vesicle Exocytosis
应用备注 FACS = 1:10-50, WB = 1:1000, IHC (p) = 1:10-50
限制 仅限研究用
状态 Liquid
浓度 0.5 mg/mL
缓冲液 PBS with 0.09 % (W/V) sodium azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C/-20 °C
储存方法 DOC2A Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
有效期 6 months
厂商提供的图像
Immunohistochemistry (IHC) image for anti-Double C2-Like Domains, alpha (DOC2A) (AA 277-306), (Center) antibody (ABIN656766) DOC2A Antibody (Center) (ABIN656766) immunohistochemistry analysis in formalin fixed ...
背景 Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010 (PubMed).

Glessner, Reilly, Kim, Takahashi, Albano, Hou, Bradfield, Zhang, Sleiman, Flory, Imielinski, Frackelton, Chiavacci, Thomas, Garris, Otieno, Davidson, Weiser, Reichenberg, Davis, Friedman, Cappola, Margulies, Rader, Grant, Buxbaum, Gur, Hakonarson: "Strong synaptic transmission impact by copy number variations in schizophrenia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 23, pp. 10584-9, 2010 (PubMed).

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