DOC2A 抗体 (AA 652-749)
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- 抗原 See all DOC2A 抗体
- DOC2A (Double C2-Like Domains, alpha (DOC2A))
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抗原表位
- AA 652-749
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DOC2A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human DOC2 (AA: 652-749) expressed in E. coli.
- 克隆位点
- 2H7C4
- 亚型
- IgG1
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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- 抗原
- DOC2A (Double C2-Like Domains, alpha (DOC2A))
- 别名
- DOC2 (DOC2A 产品)
- 别名
- DOC2A antibody, doc2-A antibody, Doc2 antibody, double C2 domain alpha antibody, double C2-like domains, alpha antibody, double C2, alpha antibody, DOC2A antibody, doc2a antibody, Doc2a antibody
- 背景
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Description: This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,
Aliases: DAB2, DOC-2
- 分子量
- 82.4 kDa
- 基因ID
- 1601
- HGNC
- 5899
- 途径
- Synaptic Vesicle Exocytosis
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