Exportin 2 抗体 (N-Term)
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- 抗原 See all Exportin 2 (CSE1L) 抗体
- Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, Pig, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Exportin 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ELSDANLQTL TEYLKKTLDP DPAIRRPAEK FLESVEGNQN YPLLLLTLLE
- 预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against CSE1L. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CSE1L
- Top Product
- Discover our top product CSE1L Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 971 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))
- 别名
- CSE1L (CSE1L 产品)
- 别名
- BcDNA:LD14270 antibody, CAS antibody, CG13281 antibody, Dcas antibody, Dmel\\CG13281 antibody, cas antibody, dcas antibody, l(2)k03902 antibody, CSE1L antibody, XPO2 antibody, Exportin-2 antibody, DKFZp459E1929 antibody, 2610100P18Rik antibody, AA407533 antibody, Capts antibody, Cas antibody, Xpo2 antibody, xpo2 antibody, CSE1 antibody, CAS/CSE1 segregation protein antibody, chromosome segregation 1 like antibody, exportin-2 antibody, chromosome segregation 1-like (S. cerevisiae) antibody, CSE1 chromosome segregation 1-like (yeast) antibody, CSE1 chromosome segregation 1-like L homeolog antibody, Cas antibody, CSE1L antibody, LOC100542094 antibody, cse1l antibody, Cse1l antibody, cse1l.L antibody
- 背景
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Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the protein may play a role both in apoptosis and in cell proliferation.Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CAS, CSE1, MGC117283, MGC130036, MGC130037, XPO2
Protein Interaction Partner: ERLIN2, HUWE1, UBC, FUS, SUMO2, STAU1, SUMO1, NEDD8, ASB16, RNF2, SUZ12, PDIA3, TBCB, CKB, GINS3, BCCIP, UBFD1, CNDP2, SCLY, CHORDC1, RRAGB, GDA, NPEPPS, SLC9A3R1, KYNU, TGM2, TCEA1, SMS, RPS6KA3, MVD, LDHA, FBXO6, YWHAQ, EGFR, UBD, PTMA, CLN3, HDAC6, MMS
Protein Size: 971 - 分子量
- 110 kDa
- 基因ID
- 1434
- NCBI登录号
- NM_001316, NP_001307
- UniProt
- P55060
- 途径
- Protein targeting to Nucleus
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