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Exportin 2 抗体 (AA 1-50)

The 兔 多克隆 anti-Exportin 2 antibody is suitable to detect Exportin 2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IF, IHC, ELISA 和 IP.
产品编号 ABIN1533228
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Exportin 2 抗体 (AA 1-50) (ABIN1533228)

抗原

See all Exportin 2 (CSE1L) 抗体
Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

适用

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人, 小鼠, 大鼠

宿主

  • 39
  • 7
兔

克隆类型

  • 25
  • 21
多克隆

标记

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This Exportin 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
  • 抗原表位

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    AA 1-50

    原理

    CAS Antibody

    特异性

    CAS Polyclonal Antibody detects endogenous levels of CAS protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human CSE1L. AA range:1-50

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. Immunoprecipitation: 2-5 μg:mg lysate. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

    别名

    CSE1L

    背景

    Synonyms: CSE1L, CAS, XPO2, Exportin-2, Exp2, Cellular apoptosis susceptibility protein, Chromosome segregation 1-like protein, Importin-alpha re-exporter

    Background: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind.The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],

    Gene Name: CSE1L

    Protein Name: Exportin-2

    分子量

    110 kDa

    基因ID

    1434

    OMIM

    601342

    UniProt

    P55060

    途径

    Protein targeting to Nucleus
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