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- 抗原 See all PCSK4 抗体
- PCSK4 (Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PCSK4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- VSSWAVQVSQ GNREVERLAR KFGFVNLGPI FPDGQYFHLR HRGVVQQSLT
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against PCSK4. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PCSK4
- Top Product
- Discover our top product PCSK4 Primary Antibody
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anti-Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) (AA 1-242) antibody
PCSK4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) (AA 35-84) antibodyPCSK4 适用: 人, 小鼠, 大鼠, Cow, 犬, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) (AA 168-196) antibodyPCSK4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) (N-Term) antibodyPCSK4 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 755 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PCSK4 (Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4))
- 别名
- PCSK4 (PCSK4 产品)
- 别名
- PC4 antibody, SPC5 antibody, AI647044 antibody, L21221 antibody, NEC 3 antibody, NEC3 antibody, PCSK4 antibody, pc4 antibody, spc5 antibody, MGC146505 antibody, pcsk4 antibody, proprotein convertase subtilisin/kexin type 4 antibody, proprotein convertase subtilisin/kexin type 4 L homeolog antibody, PCSK4 antibody, Pcsk4 antibody, pcsk4 antibody, pcsk4.L antibody
- 背景
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PCSK4 is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. PCSK4 plays a role in transcriptional coactivation. PCSK4 may be involved in stabilizing the multiprotein transcription complex.Proprotein convertases, including PCSK4, are calcium-dependent serine proteases related to bacterial subtilisins and to yeast kexin. These enzymes process precursor proteins to their active forms by selective cleavage of the polypeptide at sites following paired basic amino acids. In mammals, this family comprises PC1 (MIM 162150), PC2 (MIM 162151), PC4, PC5 (MIM 600488), furin (FUR, MIM 136950), and PACE4 (MIM 167405). Substrates for these enzymes range from prohormones to precursors for growth factors to cell surface receptors and viral surface glycoproteins (Cao et al., 2001 [PubMed 11776387]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-31 AC027307.5 80201-80231 c 32-257 AY358963.1 32-257 258-655 AK057235.1 452-849 656-2528 AY358963.1 656-2528 2529-2606 AL043305.1 210-287 2607-2674 AA453604.1 1-68 c
Alias Symbols: DKFZp434B217, MGC34749, PC4, SPC5
Protein Interaction Partner: IGF2,
Protein Size: 755 - 分子量
- 83 kDa
- 基因ID
- 54760
- NCBI登录号
- NM_017573, NP_060043
- UniProt
- Q6UW60
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