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ATP6V1B2 抗体 (Middle Region)

ATP6V1B2 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 斑马鱼, Pig, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN503926
发货至: 中国
  • 抗原 See all ATP6V1B2 抗体
    ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))
    抗原表位
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 29
    • 16
    • 16
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 斑马鱼, Pig, 马
    宿主
    • 23
    • 6
    克隆类型
    • 25
    • 4
    多克隆
    标记
    • 22
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATP6V1B2 antibody is un-conjugated
    应用范围
    • 21
    • 9
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    NFIAQGPYEN RTVFETLDIG WQLLRIFPKE MLKRIPQSTL SEFYPRDSAK
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
    产品特性
    This is a rabbit polyclonal antibody against ATP6V1B2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human ATP6V1B2
    Top Product
    Discover our top product ATP6V1B2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 511 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))
    别名
    ATP6V1B2 (ATP6V1B2 产品)
    别名
    Atp6b1b2 antibody, Atp6b2 antibody, Vatb antibody, vha55 antibody, VATB antibody, ATP6B1B2 antibody, ATP6B2 antibody, HO57 antibody, VPP3 antibody, Vma2 antibody, atp6v1bb antibody, fj51e01 antibody, vatB2 antibody, wu:fj51e01 antibody, zgc:109771 antibody, AI194269 antibody, AI790362 antibody, R74844 antibody, ATPase H+ transporting V1 subunit B2 antibody, ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 S homeolog antibody, ATPase, H+ transporting, lysosomal, V1 subunit B2 antibody, ATPase, H+ transporting, lysosomal V1 subunit B2 antibody, Atp6v1b2 antibody, atp6v1b2.S antibody, ATP6V1B2 antibody, atp6v1b2 antibody
    背景
    ATP6V1B2 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. ATP6V1B2 is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ATP6B1B2, ATP6B2, HO57, VATB, VPP3, Vma2
    Protein Interaction Partner: TCF4, UBC, PBDC1, GMPPB, GANAB, SWAP70, MSH2, JUP, MSH6, XRCC6, CRMP1, HYOU1, SEC24C, CUL2, SUPT5H, SSRP1, PDE3A, CSDE1, PAN2, FN1, SRXN1, YIF1B, UNK, ZFYVE19, TUBA1C, INTS2, TRMT1, ABCF3, ATP6V1H, CCT8, SSSCA1, TUBB4B, UBA2, USP34, ATP6V1F, ZBED1, ZPR1,
    Protein Size: 511
    分子量
    56 kDa
    基因ID
    526
    NCBI登录号
    NM_001693, NP_001684
    UniProt
    P21281
    途径
    Transition Metal Ion Homeostasis, Proton Transport
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