ATP6V1B2 抗体 (N-Term)
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- 抗原 See all ATP6V1B2 抗体
- ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATP6V1B2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- VSRNYLSQPR LTYKTVSGVN GPLVILDHVK FPRYAEIVHL TLPDGTKRSG
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
- 产品特性
- This is a rabbit polyclonal antibody against ATP6V1B2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ATP6V1B2
- Top Product
- Discover our top product ATP6V1B2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 511 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))
- 别名
- ATP6V1B2 (ATP6V1B2 产品)
- 别名
- Atp6b1b2 antibody, Atp6b2 antibody, Vatb antibody, vha55 antibody, VATB antibody, ATP6B1B2 antibody, ATP6B2 antibody, HO57 antibody, VPP3 antibody, Vma2 antibody, atp6v1bb antibody, fj51e01 antibody, vatB2 antibody, wu:fj51e01 antibody, zgc:109771 antibody, AI194269 antibody, AI790362 antibody, R74844 antibody, ATPase H+ transporting V1 subunit B2 antibody, ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 S homeolog antibody, ATPase, H+ transporting, lysosomal, V1 subunit B2 antibody, ATPase, H+ transporting, lysosomal V1 subunit B2 antibody, Atp6v1b2 antibody, atp6v1b2.S antibody, ATP6V1B2 antibody, atp6v1b2 antibody
- 背景
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ATP6V1B2 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. ATP6V1B2 is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ATP6B1B2, ATP6B2, HO57, VATB, VPP3, Vma2
Protein Interaction Partner: TCF4, UBC, PBDC1, GMPPB, GANAB, SWAP70, MSH2, JUP, MSH6, XRCC6, CRMP1, HYOU1, SEC24C, CUL2, SUPT5H, SSRP1, PDE3A, CSDE1, PAN2, FN1, SRXN1, YIF1B, UNK, ZFYVE19, TUBA1C, INTS2, TRMT1, ABCF3, ATP6V1H, CCT8, SSSCA1, TUBB4B, UBA2, USP34, ATP6V1F, ZBED1, ZPR1,
Protein Size: 511 - 分子量
- 56 kDa
- 基因ID
- 526
- NCBI登录号
- NM_001693, NP_001684
- UniProt
- P21281
- 途径
- Transition Metal Ion Homeostasis, Proton Transport
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