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- 抗原 See all XAF1 抗体
- XAF1 (XiAP Associated Factor 1 (XAF1))
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This XAF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects XAF-1.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse
- 纯化方法
- Affinity chromatography
- 免疫原
- XAF-1 antibody was raised against a synthetic peptide corresponding to amino acids at the C-terminus of human XAF-1.
- 亚型
- IgG
- Top Product
- Discover our top product XAF1 Primary Antibody
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anti-XiAP Associated Factor 1 (XAF1) (AA 151-250) antibody
XAF1 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-XiAP Associated Factor 1 (XAF1) (AA 1-301) antibodyXAF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-XiAP Associated Factor 1 (XAF1) (C-Term) antibodyXAF1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-XiAP Associated Factor 1 (XAF1) (AA 172-259) antibodyXAF1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-XiAP Associated Factor 1 (XAF1) (AA 235-269), (C-Term) antibodyXAF1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB49525 unconjugated
anti-XiAP Associated Factor 1 (XAF1) (AA 1-301) antibodyXAF1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-XiAP Associated Factor 1 (XAF1) (AA 201-218) antibodyXAF1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-XiAP Associated Factor 1 (XAF1) (AA 215-264) antibodyXAF1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-XiAP Associated Factor 1 (XAF1) (AA 202-301) antibodyXAF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E5 unconjugated
anti-XiAP Associated Factor 1 (XAF1) (AA 201-218) antibodyXAF1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Immunohistochemistry on paraffin sections. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- XAF1 (XiAP Associated Factor 1 (XAF1))
- 别名
- XAF1 (XAF1 产品)
- 别名
- BIRC4BP antibody, HSXIAPAF1 antibody, XIAPAF1 antibody, Fbxo39 antibody, XIAP associated factor 1 antibody, xaf1 antibody, XAF1 antibody, Xaf1 antibody
- 背景
- XAF-1 binds to XIAP, an inhibitor of caspases-3, -7, and -9, and triggers its relocation from the cytosol to the nucleus (1,2). Overexpression of XAF-1 results in the neutralization of XIAP\'s ability to inhibit cell death (1). XAF-1 is normally expressed in all adult and fetal tissues but was found to be present in very low levels in a variety of cancer cell lines (3). In contrast, XIAP levels have been shown to be high in a majority of cell lines. Low XAF-1 and high basal expression of XIAP may therefore play a critical role in maintaining survival of cancer cell lines (2,3). Both IFN-alpha2 and IFN-beta can induce XAF-1 mRNA in all cells examined but induction of XAF-1 protein (as observed by immunoblot analysis) was seen only in cell lines sensitive to the apoptotic effects of IFNs (4).Synonyms: BIRC4-binding protein, BIRC4BP, XIAP-associated factor 1, XIAPAF1
- 基因ID
- 54739
- NCBI登录号
- NP_059993
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