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UBE2V1 抗体 (C-Term)

UBE2V1 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN501100
发货至: 中国
  • 抗原 See all UBE2V1 抗体
    UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))
    抗原表位
    • 16
    • 10
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 52
    • 20
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 49
    • 3
    克隆类型
    • 52
    多克隆
    标记
    • 16
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBE2V1 antibody is un-conjugated
    应用范围
    • 40
    • 21
    • 14
    • 13
    • 13
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects UBE2V1 / CROC1.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Ion exchange chromatography
    免疫原
    UEV1A antibody was raised against a peptide corresponding to 15 amino acids near the C- terminus of human UEV1A.
    亚型
    IgG
    Top Product
    Discover our top product UBE2V1 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 to 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))
    别名
    UBE2V1 / CROC1 (UBE2V1 产品)
    别名
    CIR1 antibody, CROC-1 antibody, CROC1 antibody, UBE2V antibody, UEV-1 antibody, UEV1 antibody, UEV1A antibody, 0610011J09Rik antibody, AI256840 antibody, D7Bwg1382e antibody, CROC-1B antibody, ubiquitin conjugating enzyme E2 V1 antibody, ubiquitin-conjugating enzyme E2 variant 1 antibody, UBE2V1 antibody, ube2v1 antibody, Ube2v1 antibody
    背景
    Ubiquitin-conjugating enzyme E2 (UEV1) was initially discovered as a protein similar in sequence and structure to the E2 ubiquitin-conjugating enzymes but lacking their enzymatic activity (1). There are at least two variants and multiple isoforms of UEV1. In particular, UEV1A (Ubiquitin-conjugating enzyme E2 variant 1 isoform A) has recently been shown to be an important component of the Toll-like receptor and IL-1R signaling pathway (reviewed in 2). Signals from these pathways are relayed by a number of downstream molecules such as MyD88 and tumor necrosis factor receptor associated factor (TRAF6), ultimately activating various kinases and transcription factors (2,3). UEV1A is part of a dimeric ubiquitin-conjugating enzyme complex also containing Ubc13 (ubiquitin-conjugating enzyme 13) that together with TRAF6 activates TAK1, a member of the mitogen-activated protein kinase kinase kinase family (4-6). The Ubc13-UEV1A complex also mediates the Lys-63 ubiquitination of TRAF-6, and this ubiquitination is essential for TAK1 activation (5).Synonyms: CROC-1, P/OKcl.19, TRAF6-regulated IKK activator 1 beta Uev1A, UBE2V, UEV-1, UEV1, Ubiquitin-conjugating enzyme E2 variant 1
    基因ID
    387522
    NCBI登录号
    NP_954595
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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