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TWEAK 抗体

TNFSF12 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN501094
发货至: 中国
  • 抗原 See all TWEAK (TNFSF12) 抗体
    TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
    适用
    • 61
    • 24
    • 14
    • 4
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 44
    • 11
    • 10
    • 2
    克隆类型
    • 55
    • 11
    • 1
    多克隆
    标记
    • 38
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TWEAK antibody is un-conjugated
    应用范围
    • 39
    • 26
    • 17
    • 13
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects TWEAK / TNFSF12.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Rat.
    纯化方法
    Peptide Affinity Chromatography
    免疫原
    Recombinant Human TWEAK.
    亚型
    IgG
    Top Product
    Discover our top product TNFSF12 Primary Antibody
  • 应用备注
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
    别名
    TWEAK / TNFSF12 (TNFSF12 产品)
    别名
    APO3L antibody, DR3LG antibody, TWEAK antibody, Apo3l antibody, Dr3l antibody, Dr3lg antibody, Tweak antibody, TNF superfamily member 12 antibody, tumor necrosis factor (ligand) superfamily, member 12 antibody, TNFSF12 antibody, Tnfsf12 antibody
    背景
    TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane (1,2). TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis (3), induction of inflammatory cytokines (4), in addition to stimulation of apoptosis (5). The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains (1). Despite its predicted molecular weight of 27 kDa, TWEAK may migrate at aberrant positions in SDS-PAGE.Synonyms: APO3 ligand, APO3L, DR3LG, TNF-related weak inducer of apoptosis, Tumor necrosis factor ligand superfamily member 12
    基因ID
    8742
    NCBI登录号
    NP_003800
    途径
    Apoptosis
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