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IDE 抗体 (Internal Region)

IDE 适用: 人, 犬 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN375106
发货至: 中国
  • 抗原 See all IDE 抗体
    IDE (Insulin-Degrading Enzyme (IDE))
    抗原表位
    • 16
    • 8
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 62
    • 27
    • 24
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 犬
    宿主
    • 51
    • 10
    • 4
    山羊
    克隆类型
    • 56
    • 9
    多克隆
    标记
    • 36
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IDE antibody is un-conjugated
    应用范围
    • 58
    • 27
    • 19
    • 14
    • 13
    • 12
    • 7
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts to Insulysin / Insulinase.
    交叉反应 (详细)
    Species reactivity (expected):Canine.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    免疫原
    Peptide with sequence C-QQYNFDRDNTE, from the internal region of the protein sequence
    Top Product
    Discover our top product IDE Primary Antibody
  • 应用备注
    Peptide ELISA: 1/32000. Western Blot: 0.1 - 0.3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0,5 mg/mL
    缓冲液
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    IDE (Insulin-Degrading Enzyme (IDE))
    别名
    Insulin-Degrading Enzyme (IDE 产品)
    别名
    zgc:162603 antibody, IDE antibody, 1300012G03Rik antibody, 4833415K22Rik antibody, AA675336 antibody, AI507533 antibody, INSDEGM antibody, INSULYSIN antibody, insulin degrading enzyme antibody, insulin-degrading enzyme antibody, metallopeptidase antibody, IDE antibody, ide antibody, LOC591315 antibody, CC1G_01115 antibody, Bm1_26615 antibody, PTRG_10875 antibody, SJAG_01430 antibody, EBI_21700 antibody, VDBG_06702 antibody, LOAG_08082 antibody, PGTG_04982 antibody, Tsp_00424 antibody, Ide antibody
    背景
    Insulin degrading enzyme (IDE) has a preferential affinity for insulin such that the presence of insulin will inhibit IDE mediated degradation of other substrates. IDE degrades a variety of other peptides including atrial natriuretic peptide and amylin. IDE catabolizes A beta and has been implicated as a candidate enzyme responsible for the degradation and clearance of A beta in the brain. IDE has also been shown to degrade the APP intracellular domain (AICD), a product of gamma secretase cleaved APP that may function in nuclear signaling.Synonyms: Abeta-degrading protease, EC=3.4.24.56, IDE, Insulin protease, Insulinase, Insulysin
    基因ID
    3416, 9606
    UniProt
    P14735
    途径
    SARS-CoV-2 Protein Interactome
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