KCNJ1 抗体 (Cytoplasmic Domain)
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- 抗原 See all KCNJ1 抗体
- KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))
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抗原表位
- Cytoplasmic Domain
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KCNJ1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- Specific for KCNJ1.
- 交叉反应
- 人
- 交叉反应 （详细）
- Other species not yet tested.
- 纯化方法
- IgG
- 免疫原
- A synthetic peptide from the cytoplasmic domain of human KCNJ1 (ROMK1, Kir1.1) conjugated to blue carrier protein was used as the antigen. The peptide is shares 92% identity with rat and mouse sequences.
- 亚型
- IgG
- Top Product
- Discover our top product KCNJ1 Primary Antibody
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anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) antibody
KCNJ1 适用: 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) (AA 165-379) antibodyKCNJ1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) (AA 178-391) antibodyKCNJ1 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) (Middle Region) antibodyKCNJ1 适用: 人, 大鼠, 小鼠, 马, Cow, 豚鼠, 兔, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) (AA 292-391) antibodyKCNJ1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) (Internal Region) antibodyVerified KCNJ1 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) (AA 216-265) antibodyKCNJ1 适用: 人, 马, Cow, 豚鼠, 兔, 犬, 猴, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) (AA 11-60), (pSer44) antibodyKCNJ1 适用: 人, 大鼠, 小鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) (AA 342-391), (C-Term), (Intracellular) antibodyKCNJ1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
- 注意事项
- Avoid freeze and thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- 有效期
- 12 months
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- 抗原
- KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))
- 别名
- KCNJ1 (KCNJ1 产品)
- 别名
- KIR1.1 antibody, ROMK antibody, ROMK1 antibody, kir1.1 antibody, romk1 antibody, Kcnj antibody, Kir1.1 antibody, Romk2 antibody, kcnj1 antibody, wu:fl37c05 antibody, zgc:63534 antibody, potassium voltage-gated channel subfamily J member 1 antibody, potassium voltage-gated channel subfamily J member 1 L homeolog antibody, potassium inwardly-rectifying channel, subfamily J, member 1 antibody, potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1 antibody, KCNJ1 antibody, kcnj1.L antibody, kcnj1 antibody, Kcnj1 antibody, kcnj1a.1 antibody
- 背景
- FUNCTION: In the kidney, probably plays a major role in potassium homeostasis. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This channel is activated by internal ATP and can be blocked by external barium. Tissue specificity: In the kidney and pancreatic islets. Lower levels in skeletal muscle, pancreas, spleen, brain, heart and liver. Subcellular location: Membrane, Multi-pass membrane protein. Involvement in disease: Defects in KCNJ1 are the cause of Bartter syndrome type 2 (BS2) also termed hyperprostanglandin E syndrome 2. BS refers to a group of autosomal recessive disorders characterized by impaired salt reabsorption in the thick ascending loop of Henle with pronounced salt wasting, hypokalemic metabolic alkalosis, and varying degrees of hypercalciuria. BS2 is a life-threatening condition beginning in utero, with marked fetal polyuria that leads to polyhydramnios and premature delivery. Another hallmark of BS2 is a marked hypercalciuria and, as a secondary consequence, the development of nephrocalcinosis and osteopenia.,Inward Rectifier,ATP-sensitive inward rectifier potassium channel 1, Potassium channel, inwardly rectifying subfamily J member 1, ATP-regulated potassium channel ROM-K, Kir1.1, ROMK1
- UniProt
- P48048
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