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KCNJ1 抗体 (Middle Region)

KCNJ1 适用: 人, 大鼠, 小鼠, Cow, 马, 犬, 豚鼠, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2776290
发货至: 中国
  • 抗原 See all KCNJ1 抗体
    KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))
    抗原表位
    • 19
    • 16
    • 8
    • 8
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 54
    • 24
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, Cow, 马, 犬, 豚鼠, 兔, 斑马鱼
    宿主
    • 69
    • 1
    • 1
    克隆类型
    • 71
    多克隆
    标记
    • 21
    • 9
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This KCNJ1 antibody is un-conjugated
    应用范围
    • 38
    • 26
    • 26
    • 25
    • 14
    • 10
    • 9
    • 8
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    LRKSLLIGSH IYGKLLKTTV TPEGETIILD QININFVVDA GNENLFFISP
    预测反应
    Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    产品特性
    This is a rabbit polyclonal antibody against KCNJ1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human KCNJ1
    Top Product
    Discover our top product KCNJ1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 391 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tobin, Tomaszewski, Braund, Hajat, Raleigh, Palmer, Caulfield, Burton, Samani: "Common variants in genes underlying monogenic hypertension and hypotension and blood pressure in the general population." in: Hypertension, Vol. 51, Issue 6, pp. 1658-64, (2008) (PubMed).

  • 抗原
    KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))
    别名
    KCNJ1 (KCNJ1 产品)
    别名
    KIR1.1 antibody, ROMK antibody, ROMK1 antibody, kir1.1 antibody, romk1 antibody, Kcnj antibody, Kir1.1 antibody, Romk2 antibody, kcnj1 antibody, wu:fl37c05 antibody, zgc:63534 antibody, potassium voltage-gated channel subfamily J member 1 antibody, potassium voltage-gated channel subfamily J member 1 L homeolog antibody, potassium inwardly-rectifying channel, subfamily J, member 1 antibody, potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1 antibody, KCNJ1 antibody, kcnj1.L antibody, kcnj1 antibody, Kcnj1 antibody, kcnj1a.1 antibody
    背景
    KCNJ1 has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for KCNJ1.Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis.Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: KIR1.1, ROMK, ROMK1
    Protein Interaction Partner: SH3RF1, UBC, SLC9A3R2, SLC9A3R1, SGK1, GOLGA3, PRKCD, IL16, CFTR,
    Protein Size: 391
    分子量
    45 kDa
    基因ID
    3758
    NCBI登录号
    NM_000220, NP_000211
    UniProt
    P48048
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