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CCL2 抗体 (Middle Region)

CCL2 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792200
发货至: 中国
  • 抗原 See all CCL2 抗体
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    抗原表位
    • 24
    • 15
    • 13
    • 10
    • 8
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 99
    • 61
    • 59
    • 18
    • 18
    • 18
    • 16
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 犬
    宿主
    • 119
    • 56
    • 8
    • 7
    • 3
    • 2
    • 2
    克隆类型
    • 135
    • 62
    多克隆
    标记
    • 110
    • 33
    • 14
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    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CCL2 antibody is un-conjugated
    应用范围
    • 138
    • 69
    • 56
    • 28
    • 26
    • 25
    • 24
    • 18
    • 15
    • 13
    • 13
    • 13
    • 12
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    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    ASYRRITSSK CPKEAVIFKT IVAKEICADP KQKWVQDSMD HLDKQTQTPK
    预测反应
    Dog: 75%, Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against CCL2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human CCL2
    Top Product
    Discover our top product CCL2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 99 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    别名
    CCL2 (CCL2 产品)
    别名
    GDCF-2 antibody, HC11 antibody, HSMCR30 antibody, MCAF antibody, MCP-1 antibody, MCP1 antibody, SCYA2 antibody, SMC-CF antibody, AI323594 antibody, JE antibody, Scya2 antibody, Sigje antibody, MCP-1A antibody, MCP1A antibody, C-C motif chemokine ligand 2 antibody, chemokine (C-C motif) ligand 2 antibody, C-C motif chemokine 2 antibody, CCL2 antibody, Ccl2 antibody, LOC101120093 antibody
    背景
    CCL2 is a chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. CCL2 augments monocyte anti-tumor activity. CCL2 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. CCL2 may be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: GDCF-2, GDCF-2 HC11, HC11, HSMCR30, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF
    Protein Interaction Partner: Ccr2, CDC45, PCNA, ORC4, ORC2, MCM7, MCM3, MCM2, CDC6, ACKR2, ACKR4, CCR5, CCR1, CCR10, MMP3, CCL2, MMP8, MMP1, VCAN, ACKR1, CCL5, CCR3,
    Protein Size: 99
    分子量
    11 kDa
    基因ID
    6347
    NCBI登录号
    NM_002982, NP_002973
    UniProt
    P13500
    途径
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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