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HADHB 抗体 (C-Term)

Name: HADHB 抗体 (C-Term)
SKU: ABIN2783232
Availability: OutOfStock

HADHB 适用: 人, 小鼠, 大鼠, Pig, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-HADHB Antibody Titration: 0.

Immunohistochemistry (IHC) image for anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) (C-Term) antibody (ABIN2783232)

IHC

3 images

(2 references)

产品编号 ABIN2783232

发货至: 中国

Datasheet as PDF

抗原 See all HADHB 抗体

HADHB (Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB))
抗原表位
15

8

7

5

5

3

1

1

1

1

1

1
C-Term

适用

人, 小鼠, 大鼠, Pig, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔, Saccharomyces cerevisiae
宿主
51

2
兔
Compatible Secondaries
克隆类型
53
多克隆
标记
20

5

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1
This HADHB antibody is un-conjugated
应用范围
41

18

13

13

11

5

4

3

3

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

LLLGPTYATP KVLEKAGLTM NDIDAFEFHE AFSGQILANF KAMDSDWFAE

预测反应

Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Yeast: 83%, Zebrafish: 86%

产品特性

This is a rabbit polyclonal antibody against HADHB. It was validated on Western Blot and immunohistochemistry.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human HADHB

Top Product

Discover our top product HADHB Primary Antibody
anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) (AA 351-400) antibody
HADHB 适用: 人, 小鼠, 大鼠, Pig, 斑马鱼, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) (AA 1-474) antibody
HADHB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) (AA 1-474) antibody
HADHB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) (AA 34-270) antibody
HADHB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) antibody
HADHB 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) (AA 35-283) antibody
HADHB 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) antibody (FITC)
HADHB 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal FITC

anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) (N-Term) antibody
HADHB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) (AA 315-342), (C-Term) antibody
HADHB 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB22183 unconjugated

anti-Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB) antibody
HADHB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 474 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Chen, Young, Chatham, Crossman, DellItalia, Shalev: "TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling." in: American journal of physiology. Heart and circulatory physiology, Vol. 311, Issue 1, pp. H64-75, (2016) (PubMed).

Gerin, Clerbaux, Haumont, Lanthier, Das, Burant, Leclercq, MacDougald, Bommer: "Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation." in: The Journal of biological chemistry, Vol. 285, Issue 44, pp. 33652-61, (2010) (PubMed).
抗原

HADHB (Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB))

别名

HADHB (HADHB 产品)

别名

ECHB antibody, MTPB antibody, TP-BETA antibody, thiolase antibody, fb14g10 antibody, wu:fb14g10 antibody, zgc:56274 antibody, 4930479F15Rik antibody, Mtpb antibody, Hadhb antibody, hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta antibody, hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta S homeolog antibody, hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit antibody, hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit antibody, HADHB antibody, hadhb.S antibody, Hadhb antibody, hadhb antibody

背景

HADHB is the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in HADHB gene result in trifunctional protein deficiency. The protein can also bind RNA and decreases the stability of some mRNAs.This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Alternatively spliced transcript variants have been found, however, their full-length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC87480, MSTP029, TP-BETA, ECHB, MTPB
Protein Interaction Partner: HUWE1, TP53, TUBG1, SUMO2, SUMO3, UBC, PARK2, PPP6R1, ADRB2, CSNK2A2, PAN2, ATF2, vpu, TIMM8B, COX17, IQCB1, SUOX, CHCHD4, TUBB1, RPS8, OPA1, HSP90AB1, HADHA, DES, GRK5, FBXO6, CDK2, LEO1, RTF1, TK1, SMN1, PSMA3, GRB7, RCC1, CDKN1A, ANXA7, Edc4, MYC, SQST
Protein Size: 474

分子量

47 kDa

基因ID

3032

NCBI登录号

NM_000183, NP_000174

UniProt

P55084

途径

Monocarboxylic Acid Catabolic Process