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HADHB 产品

(Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/enoyl-CoA Hydratase (Trifunctional Protein), beta Subunit (HADHB))

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This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Alternatively spliced transcript variants have been found\; however, their full-length nature is not known. [provided by RefSeq, Jul 2008].

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Featured HADHB Categories

HADHB 抗体

High quality antibodies with extensive validation data.

HADHB ELISA试剂盒

Reliable ELISA kits for a wide range of species.

HADHB 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HADHB 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Bat, Human, Monkey, Mouse, Pig, Rat, Zebrafish (Danio rerio)
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN604755
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN947959
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN516342
Quantity 50 μg
Datasheet Datasheet

Recommended HADHB ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956624
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956625
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1163759
Quantity 96 tests
Datasheet Datasheet

Recommended HADHB 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306326
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306325
Quantity 25 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3127905
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our HADHB Products

Downie Ruiz Velasco, Welten, Goossens, Quax, Rappsilber, Michlewski, Nossent: "Posttranscriptional Regulation of 14q32 MicroRNAs by the CIRBP and HADHB during Vascular Regeneration after Ischemia." in: Molecular therapy. Nucleic acids, Vol. 14, pp. 329-338, (2019) (PubMed).

Fan, Long, Yan, Wang, Shi, Bao, Hu, Li, Chen, Zheng, Yan: "Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets." in: The British journal of nutrition, Vol. 117, Issue 9, pp. 1222-1234, (2017) (PubMed).

Chen, Young, Chatham, Crossman, DellItalia, Shalev: "TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling." in: American journal of physiology. Heart and circulatory physiology, Vol. 311, Issue 1, pp. H64-75, (2016) (PubMed).

Gerin, Clerbaux, Haumont, Lanthier, Das, Burant, Leclercq, MacDougald, Bommer: "Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation." in: The Journal of biological chemistry, Vol. 285, Issue 44, pp. 33652-61, (2010) (PubMed).

Ribet, Montastier, Valle, Bezaire, Mazzucotelli, Mairal, Viguerie, Langin: "Peroxisome proliferator-activated receptor-alpha control of lipid and glucose metabolism in human white adipocytes." in: Endocrinology, Vol. 151, Issue 1, pp. 123-33, (2009) (PubMed).

Synonyms and alternative names related to HADHB

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta (HADHB), hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta S homeolog (hadhb.S), hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit (HADHB), hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit (Hadhb), hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta (hadhb), hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit (Hadhb), 4930479F15Rik, ECHB, fb14g10, Hadhb, MTPB, Mtpb, thiolase, TP-BETA, wu:fb14g10, zgc:56274

Protein level used designations for HADHB

  • 2-enoyl-Coenzyme A (CoA) hydratase, beta subunit
  • 3-ketoacyl-Coenzyme A (CoA) thiolase of mitochondrial trifunctional protein, beta subunit
  • acetyl-CoA acyltransferase
  • beta-ketothiolase
  • hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit
  • trifunctional enzyme subunit beta, mitochondrial
  • hydroxyacyl dehydrogenase, subunit B
  • TP-beta
  • dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit
  • mitochondrial trifunctional protein, beta subunit
  • 3-ketoacyl-Coenzyme A thiolase
  • TP-Beta
  • enoyl-Coenzyme A hydratase, beta subunit
  • trifunctional enzyme beta subunit, mitochondrial
  • dehydrogenase/3-ketoacyl-Coenzyme A thiolase
  • hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta aubunit
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